Publications by authors named "Jennifer D Venable"

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Allosteric modulation of the solute carrier transporter SLC39A8 potentiates manganese and cadmium uptake.
Kelly L Damm-Ganamet, Clara Moon, Alan D Wickenden, Mark Tichenor, Yunhui Ge, Jennifer D Venable

J Clin Invest· November 2025

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Reductive C(sp)-C(sp) Coupling Protocol to Enable Linker Exploration of Cereblon E3-Ligase BRD4 Proteolysis-Targeting Chimeras.
Kaitlyn Lovato, Danielle Loskot, Christine Gelin, Lu Zhu, Charu Chaudhry, Jennifer D Venable

J Med Chem· May 2025

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Modulating the Potency of BRD4 PROTACs at the Systems Level with Amine-Acid Coupling Reactions.
Andrew McGrath, Haiyan Huang, Jean-Francois Brazeau, Zirong Zhang, Christopher O Audu, Jennifer D Venable

J Med Chem· January 2025

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Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation.
Holger Babbe, Thomas B Sundberg, Mark Tichenor, Mark Seierstad, Genesis Bacani, Jennifer D Venable

Proc Natl Acad Sci U S A· January 2024

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Development of small molecule inhibitors of natural killer group 2D receptor (NKG2D).
Jocelyn Wang, Kohki M Nakafuku, Jeannie Ziff, Christine F Gelin, Hadi Gholami, Jennifer D Venable

Bioorg Med Chem Lett· November 2023

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Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
Aaron A Thompson, Michael B Harbut, Pei-Pei Kung, Nathan K Karpowich, Jeffrey D Branson, Jennifer D Venable

Proc Natl Acad Sci U S A· May 2023

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Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
Mark S Tichenor, John J M Wiener, Navin L Rao, Genesis M Bacani, Jianmei Wei, Jennifer D Venable

J Med Chem· November 2022

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Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation.
Charles E Hendrick, Jeff R Jorgensen, Charu Chaudhry, Iulia I Strambeanu, Jean-Francois Brazeau, Jennifer D Venable

ACS Med Chem Lett· July 2022

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Discovery of Highly Potent and Selective IRAK1 Degraders to Probe Scaffolding Functions of IRAK1 in ABC DLBCL.
Liqiang Fu, Jing Zhang, Bin Shen, Linglong Kong, Yingtao Liu, Jennifer D Venable

J Med Chem· August 2021

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Discovery of a Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase with Oral Anti-Inflammatory Activity.
Mark S Tichenor, John J M Wiener, Navin L Rao, Charlotte Pooley Deckhut, J Kent Barbay, Jennifer D Venable

ACS Med Chem Lett· May 2021

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Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease.
Kristi A Leonard, Lisa A Madge, Paul J Krawczuk, Aihua Wang, Kevin D Kreutter, Jennifer D Venable

J Med Chem· March 2020

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Functional Profiling of 2-Aminopyrimidine Histamine H4 Receptor Modulators.
Mark S Tichenor, Robin L Thurmond, Jennifer D Venable, Brad M Savall

J Med Chem· September 2015

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Agonist/antagonist modulation in a series of 2-aryl benzimidazole H4 receptor ligands.
Brad M Savall, James P Edwards, Jennifer D Venable, Daniel J Buzard, Robin Thurmond

Bioorg Med Chem Lett· June 2010

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Phosphoinositide 3-kinase gamma (PI3Kgamma) inhibitors for the treatment of inflammation and autoimmune disease.
Jennifer D Venable, Michael K Ameriks, Jonathan M Blevitt, Robin L Thurmond, Wai-Ping Fung-Leung

Recent Pat Inflamm Allergy Drug Discov· January 2010

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Small molecule inhibitors of phosphoinositide 3-kinase (PI3K) delta and gamma.
Michael K Ameriks, Jennifer D Venable

Curr Top Med Chem· October 2009

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The histamine H4 receptor in autoimmune disease.
Mai Zhang, Jennifer D Venable, Robin L Thurmond

Expert Opin Investig Drugs· November 2006

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Preparation and biological evaluation of indole, benzimidazole, and thienopyrrole piperazine carboxamides: potent human histamine h(4) antagonists.
Jennifer D Venable, Hui Cai, Wenying Chai, Curt A Dvorak, Cheryl A Grice

J Med Chem· December 2005

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The first potent and selective non-imidazole human histamine H4 receptor antagonists.
Jill A Jablonowski, Cheryl A Grice, Wenying Chai, Curt A Dvorak, Jennifer D Venable

J Med Chem· September 2003

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