Publications by authors named "Daniel C Berwick"

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The development of inhibitors of leucine-rich repeat kinase 2 (LRRK2) as a therapeutic strategy for Parkinson's disease: the current state of play.
Sonia Azeggagh, Daniel C Berwick

Br J Pharmacol· April 2022

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Building Bridges In Neuropharmacology: New therapeutic approaches for psychiatric and neurodegenerative disorders.
Alexis Bailey, Daniel C Berwick, Rosana Camarini, Cristoforo Scavone

Br J Pharmacol· April 2022

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LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same.
Daniel C Berwick, George R Heaton, Sonia Azeggagh, Kirsten Harvey

Mol Neurodegener· December 2019

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Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus.
Simone Granno, Jonathon Nixon-Abell, Daniel C Berwick, Justin Tosh, George Heaton

Sci Rep· May 2019

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The relevance of α-KLOTHO to the central nervous system: Some key questions.
Marina Minto Cararo-Lopes, Caio Henrique Yokoyama Mazucanti, Cristoforo Scavone, Elisa Mitiko Kawamoto, Daniel Charles Berwick

Ageing Res Rev· July 2017

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Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling.
Daniel C Berwick, Behzad Javaheri, Andrea Wetzel, Mark Hopkinson, Jonathon Nixon-Abell

Mol Neurodegener· January 2017

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L'RRK de Triomphe: a solution for LRRK2 GTPase activity?
Jonathon Nixon-Abell, Daniel C Berwick, Kirsten Harvey

Biochem Soc Trans· December 2016

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Protective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity.
Jonathon Nixon-Abell, Daniel C Berwick, Simone Grannó, Victoria A Spain, Craig Blackstone

Front Mol Neurosci· March 2016

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The regulation and deregulation of Wnt signaling by PARK genes in health and disease.
Daniel C Berwick, Kirsten Harvey

J Mol Cell Biol· February 2014

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A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylation.
Bernard M H Law, Victoria A Spain, Veronica H L Leinster, Ruth Chia, Alexandra Beilina, Daniel C Berwick

J Biol Chem· January 2014

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LRRK2: an éminence grise of Wnt-mediated neurogenesis?
Daniel C Berwick, Kirsten Harvey

Front Cell Neurosci· June 2013

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LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6.
Daniel C Berwick, Kirsten Harvey

Hum Mol Genet· November 2012

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The importance of Wnt signalling for neurodegeneration in Parkinson's disease.
Daniel C Berwick, Kirsten Harvey

Biochem Soc Trans· October 2012

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LRRK2 signaling pathways: the key to unlocking neurodegeneration?
Daniel C Berwick, Kirsten Harvey

Trends Cell Biol· May 2011

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A simple technique for the prediction of interacting proteins reveals a direct Brn-3a-androgen receptor interaction.
Daniel C Berwick, James K J Diss, Vishwanie S Budhram-Mahadeo, David S Latchman

J Biol Chem· May 2010

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Regulation of Brn-3a N-terminal transcriptional activity by MEK1/2-ERK1/2 signalling in neural differentiation.
Daniel C Berwick, Mattia Calissano, Jacqueline D Corness, Simon J Cook, David S Latchman

Brain Res· February 2009

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Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles.
Daniel C Berwick, Ghislaine C Dell, Gavin I Welsh, Kate J Heesom, Ingeborg Hers

J Cell Sci· December 2004

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Identifying protein kinase substrates: hunting for the organ-grinder's monkeys.
Daniel C Berwick, Jeremy M Tavaré

Trends Biochem Sci· May 2004

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The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes.
Daniel C Berwick, Ingeborg Hers, Kate J Heesom, S Kelly Moule, Jeremy M Tavare

J Biol Chem· September 2002

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