Publications by authors named "Daniel Freed"

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Pansarcoma Analysis of Cyclin-Dependent Kinase and Cyclin Outlier Gene Expression Highlights CDK7 as a Potential Therapeutic Target in Chordoma.
Daniel S Lefler, Andrew Elliott, Wei Jiang, Ubaldo Martinez-Outschoorn, Jude Al-Sabah, Daniel M Freed

JCO Precis Oncol· July 2025

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Vaccination with a replication-defective cytomegalovirus vaccine elicits a glycoprotein B-specific monoclonal antibody repertoire distinct from natural infection.
Sarah M Valencia, Eric Rochat, Melissa J Harnois, Maria Dennis, Helen S Webster, Daniel Freed

NPJ Vaccines· October 2023

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A Novel Rotavirus Reverse Genetics Platform Supports Flexible Insertion of Exogenous Genes and Enables Rapid Development of a High-Throughput Neutralization Assay.
Jiajie Wei, Scott Radcliffe, Amanda Pirrone, Meiqing Lu, Yuan Li, Daniel Freed

Viruses· September 2023

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Activity of pemetrexed in pre-clinical chordoma models and humans.
Santosh Kesari, Feng Wang, Tiffany Juarez, Shashaanka Ashili, C Pawan K Patro, Daniel M Freed

Sci Rep· May 2023

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Mapping the landscape of genetic dependencies in chordoma.
Tanaz Sharifnia, Mathias J Wawer, Amy Goodale, Yenarae Lee, Mariya Kazachkova, Daniel M Freed

Nat Commun· April 2023

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Emerging target discovery and drug repurposing opportunities in chordoma.
Daniel M Freed, Josh Sommer, Nindo Punturi

Front Oncol· October 2022

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Polymorphic Forms of Human Cytomegalovirus Glycoprotein O Protect against Neutralization of Fibroblast Entry by Antibodies Targeting Epitopes Defined by Glycoproteins H and L.
Li He, Scott Taylor, Catherine Costa, Irene Görzer, Julia Kalser, Daniel Freed

Viruses· July 2022

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A novel high throughput assay to quantify Epstein-Barr virus neutralizing antibody activity against B-cell and epithelial cell infections for vaccine and therapeutic developments.
Fengsheng Li, Daniel Freed, Gwendolyn Heidecker, Jennifer Galli, Eberhard Durr

Vaccine· June 2022

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Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Daniel Wrapp, Xiaohua Ye, Zhiqiang Ku, Hang Su, Harrison G Jones, Daniel C Freed

Sci Adv· March 2022

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Evaluation of HSV-2 gE Binding to IgG-Fc and Application for Vaccine Development.
Jennifer D Galli, Melanie Horton, Eberhard Durr, Gwendolyn J Heidecker, Daniel Freed

Vaccines (Basel)· January 2022

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Novel adjuvants enhance immune responses elicited by a replication-defective human cytomegalovirus vaccine in nonhuman primates.
Hualin Li, Morgan A Monslow, Daniel C Freed, Dan Chang, Fengsheng Li

Vaccine· December 2021

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Vaccine Hyporesponse Induced by Individual Antibiotic Treatment in Mice and Non-Human Primates Is Diminished upon Recovery of the Gut Microbiome.
Gokul Swaminathan, Michael Citron, Jianying Xiao, James E Norton, Abigail L Reens, Daniel C Freed

Vaccines (Basel)· November 2021

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Functional Evaluation and Genetic Evolution of Human T-Cell Responses After Vaccination With a Conditionally Replication-Defective Cytomegalovirus Vaccine.
Kara S Cox, Lu Zhang, Daniel C Freed, Aimin Tang, Shifang Zhang

J Infect Dis· June 2021

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A conditionally replication-defective cytomegalovirus vaccine elicits potent and diverse functional monoclonal antibodies in a phase I clinical trial.
Leike Li, Daniel C Freed, Yaping Liu, Fengsheng Li, Diane F Barrett

NPJ Vaccines· June 2021

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Potent Bispecific Neutralizing Antibody Targeting Glycoprotein B and the gH/gL/pUL128/130/131 Complex of Human Cytomegalovirus.
Hang Su, Xiaohua Ye, Daniel C Freed, Leike Li, Zhiqiang Ku

Antimicrob Agents Chemother· February 2021

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Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection.
Matthew L Goodwin, Helen S Webster, Hsuan-Yuan Wang, Jennifer A Jenks, Cody S Nelson, Daniel C Freed

Virology· September 2020

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Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step.
Xiaohua Ye, Hang Su, Daniel Wrapp, Daniel C Freed, Fengsheng Li

PLoS Pathog· August 2020

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Comparative neutralizing potencies of antibodies suggest conservation as well as mechanistic differences in human cytomegalovirus entry into epithelial and endothelial cells.
Ying Qi, Li He, Xiaohong Cui, Laura Hertel, Daniel C Freed

Virol J· April 2020

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The Effect of Stimulus Audibility on the Relationship between Pure-Tone Average and Speech Recognition in Noise Ability.
Andrew J Vermiglio, Sigfrid D Soli, Daniel J Freed, Xiangming Fang

J Am Acad Audiol· March 2020

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Modified mRNA/lipid nanoparticle-based vaccines expressing respiratory syncytial virus F protein variants are immunogenic and protective in rodent models of RSV infection.
Amy S Espeseth, Pedro J Cejas, Michael P Citron, Dai Wang, Daniel J DiStefano, Daniel C Freed

NPJ Vaccines· February 2020

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A Replication-Defective Human Cytomegalovirus Vaccine Elicits Humoral Immune Responses Analogous to Those with Natural Infection.
Yaping Liu, Daniel C Freed, Leike Li, Aimin Tang, Fengsheng Li

J Virol· December 2019

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Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas.
Takako Tabata, Matthew Petitt, June Fang-Hoover, Daniel C Freed, Fengsheng Li

Vaccines (Basel)· September 2019

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Identification of adipocyte plasma membrane-associated protein as a novel modulator of human cytomegalovirus infection.
Xiaohua Ye, Xun Gui, Daniel C Freed, Zhiqiang Ku, Leike Li

PLoS Pathog· July 2019

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Evidence-based occupational hearing screening II: validation of a screening methodology using measures of functional hearing ability.
Sigfrid D Soli, Akiko Amano-Kusumoto, Odile Clavier, Jed Wilbur, Kristen Casto, Daniel Freed

Int J Audiol· May 2018

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Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23.
Lijun Liu, Tarjani M Thaker, Daniel M Freed, Nicole Frazier, Ketan Malhotra

Structure· February 2018

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