Publications by authors named "Daniel M Freed"

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Pansarcoma Analysis of Cyclin-Dependent Kinase and Cyclin Outlier Gene Expression Highlights CDK7 as a Potential Therapeutic Target in Chordoma.
Daniel S Lefler, Andrew Elliott, Wei Jiang, Ubaldo Martinez-Outschoorn, Jude Al-Sabah, Daniel M Freed

JCO Precis Oncol· July 2025

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Activity of pemetrexed in pre-clinical chordoma models and humans.
Santosh Kesari, Feng Wang, Tiffany Juarez, Shashaanka Ashili, C Pawan K Patro, Daniel M Freed

Sci Rep· May 2023

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Mapping the landscape of genetic dependencies in chordoma.
Tanaz Sharifnia, Mathias J Wawer, Amy Goodale, Yenarae Lee, Mariya Kazachkova, Daniel M Freed

Nat Commun· April 2023

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Emerging target discovery and drug repurposing opportunities in chordoma.
Daniel M Freed, Josh Sommer, Nindo Punturi

Front Oncol· October 2022

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Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23.
Lijun Liu, Tarjani M Thaker, Daniel M Freed, Nicole Frazier, Ketan Malhotra

Structure· February 2018

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EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics.
Daniel M Freed, Nicholas J Bessman, Anatoly Kiyatkin, Emanuel Salazar-Cavazos, Patrick O Byrne

Cell· October 2017

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Deletion Mutations Keep Kinase Inhibitors in the Loop.
Daniel M Freed, Jin H Park, Ravi Radhakrishnan, Mark A Lemmon

Cancer Cell· April 2016

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The Dark Side of Cell Signaling: Positive Roles for Negative Regulators.
Mark A Lemmon, Daniel M Freed, Joseph Schlessinger, Anatoly Kiyatkin

Cell· March 2016

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Ligand regulation of a constitutively dimeric EGF receptor.
Daniel M Freed, Diego Alvarado, Mark A Lemmon

Nat Commun· June 2015

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Putting together structures of epidermal growth factor receptors.
Nicholas J Bessman, Daniel M Freed, Mark A Lemmon

Curr Opin Struct Biol· December 2014

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Painless vision loss.
Daniel M Freed, Terence Chu

Am Fam Physician· December 2014

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Monomeric TonB and the Ton box are required for the formation of a high-affinity transporter-TonB complex.
Daniel M Freed, Stephen M Lukasik, Arthur Sikora, Audrey Mokdad, David S Cafiso

Biochemistry· April 2013

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Lipid and membrane mimetic environments modulate spin label side chain configuration in the outer membrane protein A.
Ricardo H Flores Jiménez, Daniel M Freed, David S Cafiso

J Phys Chem B· December 2011

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Molecular origin of electron paramagnetic resonance line shapes on β-barrel membrane proteins: the local solvation environment modulates spin-label configuration.
Daniel M Freed, Ali K Khan, Peter S Horanyi, David S Cafiso

Biochemistry· October 2011

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Conformational exchange in a membrane transport protein is altered in protein crystals.
Daniel M Freed, Peter S Horanyi, Michael C Wiener, David S Cafiso

Biophys J· September 2010

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