Publications by authors named "Daniel M Brody"

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Vinblastine 20' Amides: Synthetic Analogues That Maintain or Improve Potency and Simultaneously Overcome Pgp-Derived Efflux and Resistance.
John C Lukesh, Daniel W Carney, Huijun Dong, R Matthew Cross, Vyom Shukla, Daniel M Brody

J Med Chem· September 2017

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Design of Benzoxathiazin-3-one 1,1-Dioxides as a New Class of Irreversible Serine Hydrolase Inhibitors: Discovery of a Uniquely Selective PNPLA4 Inhibitor.
Anne F Kornahrens, Armand B Cognetta, Daniel M Brody, Megan L Matthews, Benjamin F Cravatt

J Am Chem Soc· May 2017

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Total synthesis of a key series of vinblastines modified at C4 that define the importance and surprising trends in activity.
Shouliang Yang, Kuppusamy Sankar, Colin K Skepper, Timothy J Barker, John C Lukesh, Daniel M Brody

Chem Sci· February 2017

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Synthesis and evaluation of duocarmycin SA analogs incorporating the methyl 1,2,8,8a-tetrahydrocyclopropa[c]imidazolo[4,5-e]indol-4-one-6-carboxylate (CImI) alkylation subunit.
Prem B Chanda, Kristopher E Boyle, Daniel M Brody, Vyom Shukla, Dale L Boger

Bioorg Med Chem· October 2016

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Ultrapotent vinblastines in which added molecular complexity further disrupts the target tubulin dimer-dimer interface.
Daniel W Carney, John C Lukesh, Daniel M Brody, Manuela M Brütsch, Dale L Boger

Proc Natl Acad Sci U S A· August 2016

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Synthesis of a Potent Vinblastine: Rationally Designed Added Benign Complexity.
Oliver Allemann, Manuela Brutsch, John C Lukesh, Daniel M Brody, Dale L Boger

J Am Chem Soc· July 2016

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A five-membered lactone prodrug of CBI-based analogs of the duocarmycins.
Mika Uematsu, Daniel M Brody, Dale L Boger

Tetrahedron Lett· June 2015

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Inhibition of carcinoma cell motility by epoxyeicosatrienoic acid (EET) antagonists.
Kasem Nithipatikom, Daniel M Brody, Alan T Tang, Vijaya L Manthati, John R Falck

Cancer Sci· December 2010

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A practical synthesis of bridged diarylacetylenes.
Ruchi Shukla, Daniel M Brody, Sergey V Lindeman, Rajendra Rathore

J Org Chem· August 2006

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