Publications by authors named "Daniel Mao"

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Analysis of Fbox substrate adapter proteins using , a program for projection of evolutionary conservation onto protein atomic coordinates.
Elliot Sicheri, Daniel Mao, Michael Tyers, Frank Sicheri

Comput Struct Biotechnol J· September 2025

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Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor.
Frédéric Vallée, Matias Casás-Selves, Monica Bubenik, Martin Duplessis, Boubacar Sow, Daniel Mao

J Med Chem· June 2025

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Author Correction: A substrate binding model for the KEOPS tRNA modifying complex.
Jonah Beenstock, Samara Mishelle Ona, Jennifer Porat, Stephen Orlicky, Leo C K Wan, Daniel Y L Mao

Nat Commun· May 2025

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Single-Nucleus Landscape of Glial Cells and Neurons in Alzheimer's Disease.
Mengru Lu, Jiaxin Li, Qi Huang, Daniel Mao, Grace Yang

Mol Neurobiol· March 2025

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Identification of altered immune cell types and molecular mechanisms in Alzheimer's disease progression by single-cell RNA sequencing.
Hua Lin, Li Su, Daniel Mao, Grace Yang, Qi Huang

Front Aging Neurosci· November 2024

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Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Heather A Bruce, Alexander U Singer, Ekaterina V Filippova, Levi L Blazer, Jarrett J Adams, Daniel Y L Mao

Protein Sci· January 2024

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Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306.
Janek Szychowski, Robert Papp, Evelyne Dietrich, Bingcan Liu, Frédéric Vallée, Daniel Mao

J Med Chem· August 2022

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A substrate binding model for the KEOPS tRNA modifying complex.
Jonah Beenstock, Samara Mishelle Ona, Jennifer Porat, Stephen Orlicky, Leo C K Wan, Daniel Y L Mao

Nat Commun· December 2020

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A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency.
Salima Daou, Manisha Talukdar, Jinle Tang, Beihua Dong, Shuvojit Banerjee, Daniel Mao

Proc Natl Acad Sci U S A· October 2020

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Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment.
Shawn Xiong, Kristina Lorenzen, Amber L Couzens, Catherine M Templeton, Dushyandi Rajendran, Daniel Y L Mao

Structure· August 2018

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Regulation of Protein Interactions by ps ne inder (MOB1) Phosphorylation.
Shawn Xiong, Amber L Couzens, Michelle J Kean, Daniel Y Mao, Sebastian Guettler

Mol Cell Proteomics· June 2017

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MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway.
Amber L Couzens, Shawn Xiong, James D R Knight, Daniel Y Mao, Sebastian Guettler

Mol Cell Proteomics· June 2017

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Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Hao Huang, Elton Zeqiraj, Beihua Dong, Babal Kant Jha, Nicole M Duffy, Daniel Y L Mao

Mol Cell· January 2014

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Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system.
Leo C K Wan, Daniel Y L Mao, Dante Neculai, Jonathan Strecker, David Chiovitti

Nucleic Acids Res· July 2013

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Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization.
Hugo Lavoie, Neroshan Thevakumaran, Gwenaëlle Gavory, John J Li, Abbas Padeganeh, Daniel Y L Mao

Nat Chem Biol· July 2013

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Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and function.
Tamadher A Alghamdi, Cheuk Y Ho, Amra Mrakovic, Danielle Taylor, Daniel Mao

J Biol Chem· March 2013

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OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function.
Yu-Chi Juang, Marie-Claude Landry, Mario Sanches, Vinayak Vittal, Charles C Y Leung, Daniel Y L Mao

Mol Cell· February 2012

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Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Daniel Y L Mao, Dante Neculai, Michael Downey, Stephen Orlicky, Yosr Z Haffani

Mol Cell· October 2008

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"Unraveling the tail" of how SRPK1 phosphorylates ASF/SF2.
Daniel Y L Mao, Derek F Ceccarelli, Frank Sicheri

Mol Cell· March 2008

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CUL7 is a novel antiapoptotic oncogene.
Sam S Kim, Mary Shago, Lilia Kaustov, Paul C Boutros, James W Clendening, Daniel Y L Mao

Cancer Res· October 2007

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p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest.
Jenny S L Ho, Weili Ma, Daniel Y L Mao, Samuel Benchimol

Mol Cell Biol· September 2005

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A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants.
Antonio Pineda-Lucena, Cynthia S W Ho, Daniel Y L Mao, Yi Sheng, Rob C Laister

J Mol Biol· August 2005

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Promoter-binding and repression of PDGFRB by c-Myc are separable activities.
Daniel Y L Mao, Dalia Barsyte-Lovejoy, Cynthia S W Ho, John D Watson, Angelina Stojanova

Nucleic Acids Res· July 2004

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c-Myc represses the proximal promoters of GADD45a and GADD153 by a post-RNA polymerase II recruitment mechanism.
Dalia Barsyte-Lovejoy, Daniel Y L Mao, Linda Z Penn

Oncogene· April 2004

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Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression.
Daniel Y L Mao, John D Watson, Pearlly S Yan, Dalia Barsyte-Lovejoy, Fereshteh Khosravi

Curr Biol· May 2003

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