Publications by authors named "Daniel Sheward"

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Generation of antigen-specific paired-chain antibodies using large language models.
Perry T Wasdin, Nicole V Johnson, Alexis K Janke, Sofia Held, Toma M Marinov, Daniel J Sheward

Cell· December 2025

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Synthetic coevolution reveals adaptive mutational trajectories of neutralizing antibodies and SARS-CoV-2.
Roy A Ehling, Mason Minot, Max D Overath, Daniel J Sheward, Jiami Han

Cell Syst· September 2025

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Generation of antigen-specific paired chain antibody sequences using large language models.
Perry T Wasdin, Nicole V Johnson, Alexis K Janke, Sofia Held, Toma M Marinov, Daniel J Sheward

bioRxiv· March 2025

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Isolation and characterization of IgG3 glycan-targeting antibodies with exceptional cross-reactivity for diverse viral families.
Matthew J Vukovich, Andrea R Shiakolas, Jared Lindenberger, Robert A Richardson, Lindsay E Bass, Daniel J Sheward

PLoS Pathog· September 2024

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Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaques.
Marco Mandolesi, Hrishikesh Das, Liset de Vries, Yiqiu Yang, Changil Kim, Daniel J Sheward

Nat Commun· July 2024

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Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies.
Daniel J Sheward, Pradeepa Pushparaj, Hrishikesh Das, Allison J Greaney, Changil Kim

Cell Rep Med· June 2024

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Humoral immune responses to the monovalent XBB.1.5-adapted BNT162b2 mRNA booster in Sweden.
Ulrika Marking, Oscar Bladh, Katherina Aguilera, Yiqiu Yang, Nina Greilert Norin, Daniel J Sheward

Lancet Infect Dis· February 2024

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Three immunizations with Novavax's protein vaccines increase antibody breadth and provide durable protection from SARS-CoV-2.
Klara Lenart, Rodrigo Arcoverde Cerveira, Fredrika Hellgren, Sebastian Ols, Daniel J Sheward

NPJ Vaccines· January 2024

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Sensitivity of the SARS-CoV-2 BA.2.86 variant to prevailing neutralising antibody responses.
Daniel J Sheward, Yiqiu Yang, Michelle Westerberg, Sofia Öling, Sandra Muschiol

Lancet Infect Dis· November 2023

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SARS-CoV-2 evolution in the Omicron era.
Cornelius Roemer, Daniel J Sheward, Ryan Hisner, Federico Gueli, Hitoshi Sakaguchi

Nat Microbiol· November 2023

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SARS-CoV-2 antibodies from children exhibit broad neutralization and belong to adult public clonotypes.
Steven C Wall, Naveenchandra Suryadevara, Changil Kim, Andrea R Shiakolas, Clinton M Holt, Daniel J Sheward

Cell Rep Med· November 2023

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Antigen receptor stimulation induces purifying selection against pathogenic mitochondrial tRNA mutations.
Jingdian Zhang, Camilla Koolmeister, Jinming Han, Roberta Filograna, Leo Hanke, Daniel J Sheward

JCI Insight· September 2023

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Vaccine-induced correlate of protection against fatal COVID-19 in older and frail adults during waves of neutralization-resistant variants of concern: an observational study.
Linnea Vikström, Peter Fjällström, Yong-Dae Gwon, Daniel J Sheward, Julia Wigren-Byström

Lancet Reg Health Eur· May 2023

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Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages.
Mark Chernyshev, Mrunal Sakharkar, Ruth I Connor, Haley L Dugan, Daniel J Sheward

Nat Commun· April 2023

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Frequent use of IGHV3-30-3 in SARS-CoV-2 neutralizing antibody responses.
Pradeepa Pushparaj, Andrea Nicoletto, Xaquin Castro Dopico, Daniel J Sheward, Sungyong Kim

Front Virol· March 2023

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SARS-CoV-2 spike HexaPro formulated in aluminium hydroxide and administered in an accelerated vaccination schedule partially protects Syrian Hamsters against viral challenge despite low neutralizing antibody responses.
Dennis Christensen, Charlotta Polacek, Daniel J Sheward, Leo Hanke, Gerald McInerney

Front Immunol· February 2023

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Longitudinal single-cell analysis of SARS-CoV-2-reactive B cells uncovers persistence of early-formed, antigen-specific clones.
Lydia Scharf, Hannes Axelsson, Aikaterini Emmanouilidi, Nimitha R Mathew, Daniel J Sheward

JCI Insight· January 2023

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Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Pradeepa Pushparaj, Andrea Nicoletto, Daniel J Sheward, Hrishikesh Das, Xaquin Castro Dopico

Immunity· January 2023

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Silver nanoparticles with excellent biocompatibility block pseudotyped SARS-CoV-2 in the presence of lung surfactant.
Govind Gupta, Bejan Hamawandi, Daniel J Sheward, Ben Murrell, Leo Hanke

Front Bioeng Biotechnol· December 2022

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Omicron sublineage BA.2.75.2 exhibits extensive escape from neutralising antibodies.
Daniel J Sheward, Changil Kim, Julian Fischbach, Kenta Sato, Sandra Muschiol

Lancet Infect Dis· November 2022

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Evasion of neutralising antibodies by omicron sublineage BA.2.75.
Daniel J Sheward, Changil Kim, Julian Fischbach, Sandra Muschiol, Roy A Ehling

Lancet Infect Dis· October 2022

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Protection against SARS-CoV-2 transmission by a parenteral prime-Intranasal boost vaccine strategy.
Dennis Christensen, Charlotta Polacek, Daniel J Sheward, Leo Hanke, Ainhoa Moliner-Morro

EBioMedicine· October 2022

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HIV Coinfection Provides Insights for the Design of Vaccine Cocktails to Elicit Broadly Neutralizing Antibodies.
Daniel J Sheward, Tandile Hermanus, Ben Murrell, Nigel Garrett, Salim S Abdool Karim

J Virol· July 2022

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Neutralisation sensitivity of the SARS-CoV-2 omicron (B.1.1.529) variant: a cross-sectional study.
Daniel J Sheward, Changil Kim, Roy A Ehling, Alec Pankow, Xaquin Castro Dopico

Lancet Infect Dis· June 2022

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Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies.
Leo Hanke, Daniel J Sheward, Alec Pankow, Laura Perez Vidakovics, Vivien Karl

Sci Adv· March 2022

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