Publications by authors named "Daniela Brunner"

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Enrichment analysis of phenotypic data for drug repurposing in rare diseases.
Alberto Ambesi-Impiombato, Kimberly Cox, Sylvie Ramboz, Daniela Brunner, Mukesh Bansal

Front Pharmacol· July 2023

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Benefits of global mutant huntingtin lowering diminish over time in a Huntington's disease mouse model.
Deanna M Marchionini, Jeh-Ping Liu, Alberto Ambesi-Impiombato, Kimberly Kerker, Kim Cirillo, Daniela Brunner

JCI Insight· October 2022

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Inhibition of MEK-ERK signaling reduces seizures in two mouse models of tuberous sclerosis complex.
Lena H Nguyen, Steven C Leiser, Dekun Song, Daniela Brunner, Steven L Roberds

Epilepsy Res· March 2022

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Comparing the Pfizer Central Nervous System Multiparameter Optimization Calculator and a BBB Machine Learning Model.
Fabio Urbina, Kimberley M Zorn, Daniela Brunner, Sean Ekins

ACS Chem Neurosci· June 2021

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Crowdsourcing digital health measures to predict Parkinson's disease severity: the Parkinson's Disease Digital Biomarker DREAM Challenge.
Solveig K Sieberts, Jennifer Schaff, Marlena Duda, Bálint Ármin Pataki, Ming Sun, Daniela Brunner

NPJ Digit Med· March 2021

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Microbiome dynamics during the HI-SEAS IV mission, and implications for future crewed missions beyond Earth.
Alexander Mahnert, Cyprien Verseux, Petra Schwendner, Kaisa Koskinen, Christina Kumpitsch, Daniela Brunner

Microbiome· January 2021

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Novel brain permeant mTORC1/2 inhibitors are as efficacious as rapamycin or everolimus in mouse models of acquired partial epilepsy and tuberous sclerosis complex.
Wiebke Theilmann, Birthe Gericke, Alina Schidlitzki, Syed Muhammad Muneeb Anjum, Saskia Borsdorf, Daniela Brunner

Neuropharmacology· December 2020

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Mouse model systems of autism spectrum disorder: Replicability and informatics signature.
Patricia Kabitzke, Diana Morales, Dansha He, Kimberly Cox, Jane Sutphen, Daniela Brunner

Genes Brain Behav· September 2020

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Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.
Abdellatif Benraiss, Su Wang, Stephanie Herrlinger, Xiaojie Li, Devin Chandler-Militello, Daniela Brunner

Nat Commun· June 2016

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Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder.
Daniela Brunner, Patricia Kabitzke, Dansha He, Kimberly Cox, Lucinda Thiede

PLoS One· May 2016

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Cognitive Training at a Young Age Attenuates Deficits in the zQ175 Mouse Model of HD.
Paul C P Curtin, Andrew M Farrar, Stephen Oakeshott, Jane Sutphen, Jason Berger, Daniela Brunner

Front Behav Neurosci· January 2016

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Plectin reinforces vascular integrity by mediating crosstalk between the vimentin and the actin networks.
Selma Osmanagic-Myers, Stefanie Rus, Michael Wolfram, Daniela Brunner, Wolfgang H Goldmann

J Cell Sci· November 2015

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Multigram synthesis and in vivo efficacy studies of a novel multitarget anti-Alzheimer's compound.
Irene Sola, Elisabet Viayna, Tània Gómez, Carles Galdeano, Matteo Cassina, Daniela Brunner

Molecules· March 2015

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Animal models of Huntington's disease for translation to the clinic: best practices.
Liliana Menalled, Daniela Brunner

Mov Disord· September 2014

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Characterization of rat serum amyloid A4 (SAA4): a novel member of the SAA superfamily.
Christine Rossmann, Christian Windpassinger, Daniela Brunner, Alenka Kovacevic, Natascha Schweighofer

Biochem Biophys Res Commun· August 2014

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Measuring reinforcement learning and motivation constructs in experimental animals: relevance to the negative symptoms of schizophrenia.
Athina Markou, John D Salamone, Timothy J Bussey, Adam C Mar, Daniela Brunner

Neurosci Biobehav Rev· November 2013

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Chemistry, pharmacology, and behavioral studies identify chiral cyclopropanes as selective α4β2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile. Part II.
Han-Kun Zhang, Li-Fang Yu, J Brek Eaton, Paul Whiteaker, Oluseye K Onajole, Daniela Brunner

J Med Chem· July 2013

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Insights into the structural determinants required for high-affinity binding of chiral cyclopropane-containing ligands to α4β2-nicotinic acetylcholine receptors: an integrated approach to behaviorally active nicotinic ligands.
Han-Kun Zhang, J Brek Eaton, Li-Fang Yu, Mieke Nys, Angelica Mazzolari, Daniela Brunner

J Med Chem· September 2012

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Chemistry and behavioral studies identify chiral cyclopropanes as selective α4β2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile.
Hankun Zhang, Werner Tückmantel, J Brek Eaton, Po-Wai Yuen, Li-Fang Yu, Daniela Brunner

J Med Chem· January 2012

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The novel triple reuptake inhibitor JZAD-IV-22 exhibits an antidepressant pharmacological profile without locomotor stimulant or sensitization properties.
Barbara J Caldarone, Neil E Paterson, Jia Zhou, Daniela Brunner, Alan P Kozikowski

J Pharmacol Exp Ther· December 2010

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Comprehensive behavioral testing in the R6/2 mouse model of Huntington's disease shows no benefit from CoQ10 or minocycline.
Liliana B Menalled, Monica Patry, Natalie Ragland, Phillip A S Lowden, Jennifer Goodman, Daniela Brunner

PLoS One· March 2010

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Reward-seeking and discrimination deficits displayed by hypodopaminergic mice are prevented in mice lacking dopamine D4 receptors.
Sergio I Nemirovsky, M Elena Avale, Daniela Brunner, Marcelo Rubinstein

Synapse· November 2009

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Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.
Liliana Menalled, Bassem F El-Khodor, Monica Patry, Mayte Suárez-Fariñas, Samantha J Orenstein, Daniela Brunner

Neurobiol Dis· September 2009

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Acquisition of peak responding: what is learned?
Fuat Balci, Charles R Gallistel, Brian D Allen, Krystal M Frank, Jacqueline M Gibson, Daniela Brunner

Behav Processes· January 2009

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Pharmacological manipulations of interval timing using the peak procedure in male C3H mice.
Fuat Balci, Elliot A Ludvig, Jacqueline M Gibson, Brian D Allen, Krystal M Frank, Daniela Brunner

Psychopharmacology (Berl)· November 2008

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