Publications by authors named "Darcy Bates"

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Confounding off-target effects of BH3 mimetics at commonly used concentrations: MIM1, UMI-77, and A-1210477.
David J Mallick, Ryan S Soderquist, Darcy Bates, Alan Eastman

Cell Death Dis· February 2019

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Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer.
Riley A Hampsch, Kevin Shee, Darcy Bates, Lionel D Lewis, Laurent Désiré

Oncotarget· March 2017

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Microtubule destabilising agents: far more than just antimitotic anticancer drugs.
Darcy Bates, Alan Eastman

Br J Clin Pharmacol· February 2017

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Rapid induction of apoptosis in chronic lymphocytic leukemia cells by the microtubule disrupting agent BNC105.
Darcy Bates, Edmond J Feris, Alexey V Danilov, Alan Eastman

Cancer Biol Ther· January 2017

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Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha-Positive, PIK3CA-Mutant Breast Cancer.
Wei Yang, Sarah R Hosford, Lloye M Dillon, Kevin Shee, Stephanie C Liu, Darcy Bates

Clin Cancer Res· May 2016

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Vincristine activates c-Jun N-terminal kinase in chronic lymphocytic leukaemia in vivo.
Darcy J P Bates, Lionel D Lewis, Alan Eastman, Alexey V Danilov

Br J Clin Pharmacol· September 2015

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Manipulating the apoptotic pathway: potential therapeutics for cancer patients.
Darcy J P Bates, Lionel D Lewis

Br J Clin Pharmacol· September 2013

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Toward a cure for chronic lymphocytic leukemia: an attack on multiple fronts.
Alexey V Danilov, Ryan S Soderquist, Darcy J P Bates, Alan Eastman

Expert Rev Anticancer Ther· September 2013

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Vinblastine rapidly induces NOXA and acutely sensitizes primary chronic lymphocytic leukemia cells to ABT-737.
Darcy J P Bates, Alexey V Danilov, Christopher H Lowrey, Alan Eastman

Mol Cancer Ther· August 2013

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Nitroalkene fatty acids mediate activation of Nrf2/ARE-dependent and PPARγ-dependent transcription by distinct signaling pathways and with significantly different potencies.
Darcy J P Bates, Pamela K Smitherman, Alan J Townsend, S Bruce King, Charles S Morrow

Biochemistry· September 2011

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Vinblastine sensitizes leukemia cells to cyclin-dependent kinase inhibitors, inducing acute cell cycle phase-independent apoptosis.
Darcy J P Bates, Bethany L Salerni, Christopher H Lowrey, Alan Eastman

Cancer Biol Ther· August 2011

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Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and up-regulating BH3-only protein NOXA.
Tina C Albershardt, Bethany L Salerni, Ryan S Soderquist, Darcy J P Bates, Alexandre A Pletnev

J Biol Chem· July 2011

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Vinblastine induces acute, cell cycle phase-independent apoptosis in some leukemias and lymphomas and can induce acute apoptosis in others when Mcl-1 is suppressed.
Bethany L Salerni, Darcy J Bates, Tina C Albershardt, Christopher H Lowrey, Alan Eastman

Mol Cancer Ther· April 2010

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Noncatalytic interactions between glutathione S-transferases and nitroalkene fatty acids modulate nitroalkene-mediated activation of peroxisomal proliferator-activated receptor gamma.
Darcy J P Bates, Mark O Lively, Michael J Gorczynski, S Bruce King, Alan J Townsend

Biochemistry· May 2009

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Modulation of nitrated lipid signaling by multidrug resistance protein 1 (MRP1): glutathione conjugation and MRP1-mediated efflux inhibit nitrolinoleic acid-induced, PPARgamma-dependent transcription activation.
Richard L Alexander, Darcy J P Bates, Marcus W Wright, S Bruce King, Charles S Morrow

Biochemistry· June 2006

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