Publications by authors named "Darrell Smith"

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Vancomycin Monitoring for Treatment of Acute Pulmonary Exacerbations of Adult Cystic Fibrosis Patients.
Darrell Smith, James Sanders, Marguerite Monogue

Pulm Med· June 2025

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Muscarinic acetylcholine type 1 receptor antagonism activates TRPM3 to augment mitochondrial function and drive axonal repair in adult sensory neurons.
Sanjana Chauhan, Darrell R Smith, Shiva Shariati-Ievari, Abhay Srivastava, Sanjiv Dhingra

Mol Metab· February 2025

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A muscarinic receptor antagonist reverses multiple indices of diabetic peripheral neuropathy: preclinical and clinical studies using oxybutynin.
Carolina M Casselini, Henri K Parson, Katie E Frizzi, Alex Marquez, Darrell R Smith

Acta Neuropathol· March 2024

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CEBPβ regulation of endogenous IGF-1 in adult sensory neurons can be mobilized to overcome diabetes-induced deficits in bioenergetics and axonal outgrowth.
Mohamad-Reza Aghanoori, Prasoon Agarwal, Evan Gauvin, Raghu S Nagalingam, Raiza Bonomo, Darrell R Smith

Cell Mol Life Sci· March 2022

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Sensory neurons derived from diabetic rats exhibit deficits in functional glycolysis and ATP that are ameliorated by IGF-1.
Mohamad-Reza Aghanoori, Vicky Margulets, Darrell R Smith, Lorrie A Kirshenbaum, Daniel Gitler

Mol Metab· July 2021

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Muscarinic Toxin 7 Signals Via Ca/Calmodulin-Dependent Protein Kinase Kinase β to Augment Mitochondrial Function and Prevent Neurodegeneration.
Ali Saleh, Mohammad Golam Sabbir, Mohamad-Reza Aghanoori, Darrell R Smith, Subir K Roy Chowdhury

Mol Neurobiol· June 2020

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Insulin-like growth factor-1 activates AMPK to augment mitochondrial function and correct neuronal metabolism in sensory neurons in type 1 diabetes.
Mohamad-Reza Aghanoori, Darrell R Smith, Shiva Shariati-Ievari, Andrew Ajisebutu, Annee Nguyen

Mol Metab· February 2019

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High glucose concentration suppresses a SIRT2 regulated pathway that enhances neurite outgrowth in cultured adult sensory neurons.
Emily Schartner, Mohammad Golam Sabbir, Ali Saleh, Rafaela Vieira Silva, Subir Roy Chowdhury, Darrell R Smith

Exp Neurol· November 2018

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Depressed mitochondrial function and electron transport Complex II-mediated HO production in the cortex of type 1 diabetic rodents.
Subir Roy Chowdhury, Jelena Djordjevic, Ella Thomson, Darrell R Smith, Benedict C Albensi

Mol Cell Neurosci· May 2018

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Insulin prevents aberrant mitochondrial phenotype in sensory neurons of type 1 diabetic rats.
Mohamad-Reza Aghanoori, Darrell R Smith, Subir Roy Chowdhury, Mohammad Golam Sabbir, Nigel A Calcutt

Exp Neurol· November 2017

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Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy.
Nigel A Calcutt, Darrell R Smith, Katie Frizzi, Mohammad Golam Sabbir, Subir K Roy Chowdhury

J Clin Invest· February 2017

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The proinflammatory cytokine, interleukin-17A, augments mitochondrial function and neurite outgrowth of cultured adult sensory neurons derived from normal and diabetic rats.
Tarek Habash, Ali Saleh, Subir K Roy Chowdhury, Darrell R Smith, Paul Fernyhough

Exp Neurol· November 2015

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Ciliary neurotrophic factor reverses aberrant mitochondrial bioenergetics through the JAK/STAT pathway in cultured sensory neurons derived from streptozotocin-induced diabetic rodents.
Subir Roy Chowdhury, Ali Saleh, Eli Akude, Darrell R Smith, Dwane Morrow

Cell Mol Neurobiol· July 2014

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Temporal dystrophic remodeling within the intrinsic cardiac nervous system of the streptozotocin-induced diabetic rat model.
Chantalle E Menard, Melanie Durston, Elena Zherebitskaya, Darrell R Smith, Darren Freed

Acta Neuropathol Commun· June 2014

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Receptor for advanced glycation end-products (RAGE) activates divergent signaling pathways to augment neurite outgrowth of adult sensory neurons.
Ali Saleh, Darrell R Smith, Lori Tessler, Abigail R Mateo, Corina Martens

Exp Neurol· November 2013

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Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through JAK/STAT3 modulation of mitochondrial bioenergetics in adult sensory neurons.
Ali Saleh, Subir K Roy Chowdhury, Darrell R Smith, Savitha Balakrishnan, Lori Tessler

Mol Brain· October 2013

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The role of aberrant mitochondrial bioenergetics in diabetic neuropathy.
Subir K Roy Chowdhury, Darrell R Smith, Paul Fernyhough

Neurobiol Dis· March 2013

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Ciliary neurotrophic factor activates NF-κB to enhance mitochondrial bioenergetics and prevent neuropathy in sensory neurons of streptozotocin-induced diabetic rodents.
Ali Saleh, Subir K Roy Chowdhury, Darrell R Smith, Savitha Balakrishnan, Lori Tessler

Neuropharmacology· February 2013

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Color stability of composite resin cements.
Darrell S Smith, Kraig S Vandewalle, Gerry Whisler

Gen Dent· July 2012

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Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes.
Subir K Roy Chowdhury, Darrell R Smith, Ali Saleh, Jason Schapansky, Alexandra Marquez

Brain· June 2012

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Sensory neurons derived from diabetic rats have diminished internal Ca2+ stores linked to impaired re-uptake by the endoplasmic reticulum.
Elena Zherebitskaya, Jason Schapansky, Eli Akude, Darrell R Smith, Randy Van der Ploeg

ASN Neuro· January 2012

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Tumor necrosis factor-α elevates neurite outgrowth through an NF-κB-dependent pathway in cultured adult sensory neurons: Diminished expression in diabetes may contribute to sensory neuropathy.
Ali Saleh, Darrell R Smith, Savitha Balakrishnan, Lori Dunn, Corina Martens

Brain Res· November 2011

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Diminished superoxide generation is associated with respiratory chain dysfunction and changes in the mitochondrial proteome of sensory neurons from diabetic rats.
Eli Akude, Elena Zherebitskaya, Subir K Roy Chowdhury, Darrell R Smith, Rick T Dobrowsky

Diabetes· January 2011

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Mitochondrial respiratory chain dysfunction in dorsal root ganglia of streptozotocin-induced diabetic rats and its correction by insulin treatment.
Subir K Roy Chowdhury, Elena Zherebitskaya, Darrell R Smith, Eli Akude, Sharmila Chattopadhyay

Diabetes· April 2010

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Negative pressure fixation device to reduce motion artifacts on contrast-enhanced MRI of the breast: a clinical feasibility study.
Asha Balakrishnan, Daniel F Kacher, Eva Gombos, Darrell N Smith, Macarena Carretero

J Magn Reson Imaging· August 2009

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