Publications by authors named "Dat Ha"

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Requirements for nuclear GRP78 transcriptional regulatory activities and interaction with nuclear GRP94.
Ze Liu, Dat P Ha, Liangguang Leo Lin, Ling Qi, Amy S Lee

J Biol Chem· April 2025

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Water Hammer Phenomenon in Coronary Arteries: Scientific Basis for Diagnostic and Predictive Modeling with Acoustic Action Mapping.
Khiem D Ngo, Thach Nguyen, Huan Dat Pham, Hadrian Tran, Dat Q Ha, Imran Mihas, Mihas Kodenchery, C Michael Gibson, Thang Nguyen

Diagnostics (Basel)· February 2025

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Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin.
Heehwa G Son, Dat Thinh Ha, Yun Xia, Tiancheng Li, Jasmine Blandin, Yuhan Zeng, Tatsuya Hasegawa, Jonathan L Messerschmidt, Shadmehr Demehri

Cancer Cell· January 2025

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GRP78 inhibitor YUM70 upregulates 4E-BP1 and suppresses c-MYC expression and viability of oncogenic c-MYC tumors.
Vicky Yamamoto, Dat P Ha, Ze Liu, Miller Huang, Soma Samanta

Neoplasia· September 2024

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Targeting stress induction of GRP78 by cardiac glycoside oleandrin dually suppresses cancer and COVID-19.
Dat P Ha, Woo-Jin Shin, Ze Liu, Michael E Doche, Roy Lau, Shannon M Mumenthaler

Cell Biosci· September 2024

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ER chaperone GRP78/BiP translocates to the nucleus under stress and acts as a transcriptional regulator.
Ze Liu, Guanlin Liu, Dat P Ha, Justin Wang, Min Xiong

Proc Natl Acad Sci U S A· August 2023

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GRP78 Inhibitor YUM70 Suppresses SARS-CoV-2 Viral Entry, Spike Protein Production and Ameliorates Lung Damage.
Dat P Ha, Woo-Jin Shin, Juan Carlos Hernandez, Nouri Neamati, Louis Dubeau

Viruses· May 2023

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Ag/SiO nanoparticles stabilization with lignin derived from rice husk for antifungal and antibacterial activities.
Nhat Thong Tran, Dat Ha, Lam H Pham, Tuan Vu Vo, Nguyen Ngan Nguyen, Cong Khanh Tran, Thi Thanh Van Tran

Int J Biol Macromol· March 2023

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Compromised T Cell Immunity Links Increased Cutaneous Papillomavirus Activity to Squamous Cell Carcinoma Risk.
Luke H Johnson, Heehwa G Son, Dat Thinh Ha, John D Strickley, Joongho Joh, Shadmehr Demehri

JID Innov· March 2023

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Targeting GRP78 suppresses oncogenic KRAS protein expression and reduces viability of cancer cells bearing various KRAS mutations.
Dat P Ha, Bo Huang, Han Wang, Daisy Flores Rangel, Richard Van Krieken

Neoplasia· November 2022

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The stress-inducible ER chaperone GRP78/BiP is upregulated during SARS-CoV-2 infection and acts as a pro-viral protein.
Woo-Jin Shin, Dat P Ha, Keigo Machida, Amy S Lee

Nat Commun· November 2022

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Trending Anti-E7 Serology Predicts Mortality and Recurrence of HPV-Associated Cancers of the Oropharynx.
Luke Johnson, Dat T Ha, Melissa B Hall, Gregory Shoemaker, Paul A Bevins, Shadmehr Demehri

J Oncol· September 2022

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Cancer Diagnostics and Early Detection Using Electrochemical Aptasensors.
Joel Imoukhuede Omage, Ethan Easterday, Jelonia T Rumph, Imamulhaq Brula, Braxton Hill, Dat Thinh Ha, Michael K Danquah

Micromachines (Basel)· March 2022

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Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress induction.
Dat P Ha, Yuan-Li Tsai, Amy S Lee

Neoplasia· December 2021

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Highly Functional Materials Based on Nano-Lignin, Lignin, and Lignin/Silica Hybrid Capped Silver Nanoparticles with Antibacterial Activities.
Nhat Thong Tran, Trang Thi Thu Nguyen, Dat Ha, Thu Hien Nguyen, Nguyen Ngan Nguyen, Cong Khanh Tran, Thi Thanh Van Tran

Biomacromolecules· December 2021

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The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection.
Anthony J Carlos, Dat P Ha, Da-Wei Yeh, Richard Van Krieken, Chun-Chih Tseng, Pu Zhang

J Biol Chem· July 2021

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ER residential chaperone GRP78 unconventionally relocalizes to the cell surface via endosomal transport.
Richard Van Krieken, Yuan-Li Tsai, Anthony J Carlos, Dat P Ha, Amy S Lee

Cell Mol Life Sci· June 2021

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Graphene Oxide-Based Simple and Rapid Detection of Antibiotic Resistance Gene via Quantum Dot-Labeled Zinc Finger Proteins.
Dat Thinh Ha, Van-Thuan Nguyen, Moon-Soo Kim

Anal Chem· June 2021

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Endoplasmic reticulum chaperone GRP78/BiP is critical for mutant Kras-driven lung tumorigenesis.
Daisy Flores Rangel, Louis Dubeau, Ryan Park, Priscilla Chan, Dat P Ha

Oncogene· May 2021

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Insulin-like growth factor 1-receptor signaling stimulates GRP78 expression through the PI3K/AKT/mTOR/ATF4 axis.
Dat P Ha, Amy S Lee

Cell Signal· November 2020

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The stress-inducible molecular chaperone GRP78 as potential therapeutic target for coronavirus infection.
Dat P Ha, Richard Van Krieken, Anthony J Carlos, Amy S Lee

J Infect· September 2020

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Immunity to commensal papillomaviruses protects against skin cancer.
John D Strickley, Jonathan L Messerschmidt, Mary E Awad, Tiancheng Li, Tatsuya Hasegawa, Dat Thinh Ha, Shadmehr Demehri

Nature· November 2019

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Pathogen-specific DNA sensing with engineered zinc finger proteins immobilized on a polymer chip.
Dat Thinh Ha, Sthitodhi Ghosh, Chong H Ahn, David J Segal, Moon-Soo Kim

Analyst· August 2018

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Suppression of stress induction of the 78-kilodalton glucose regulated protein (GRP78) in cancer by IT-139, an anti-tumor ruthenium small molecule inhibitor.
Suzanne J Bakewell, Daisy F Rangel, Dat P Ha, Jyothi Sethuraman, Richard Crouse, Emma Hadley

Oncotarget· July 2018

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Endoplasmic reticulum stress activates SRC, relocating chaperones to the cell surface where GRP78/CD109 blocks TGF-β signaling.
Yuan-Li Tsai, Dat P Ha, He Zhao, Anthony J Carlos, Shan Wei

Proc Natl Acad Sci U S A· May 2018

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