Publications by authors named "David A Brow"

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Substitutions in RNA-binding protein Hrp1 map a potential interaction surface with the yeast RNA polymerase II elongation complex.
Moyao Wang, Payal Arora, Craig D Kaplan, David A Brow

Genetics· October 2025

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Direct RNA-seq provides evidence for an antiterminator function of the yeast Hrp1 protein on RNA polymerase II transcripts.
Emma C Goguen, Kylie A Zawisza, David A Brow

bioRxiv· September 2025

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Substitutions in RNA-binding protein Hrp1 map a potential interaction surface with the yeast RNA polymerase II elongation complex.
Moyao Wang, Payal Arora, Craig D Kaplan, David A Brow

bioRxiv· May 2025

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Live-cell analysis of IMPDH protein levels during yeast colony growth provides insights into the regulation of GTP synthesis.
Erica L Shand, Kieran Sweeney, Kaitlin E Sundling, Megan N McClean, David A Brow

mBio· August 2024

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Domains and residues of the Saccharomyces cerevisiae hnRNP protein Hrp1 important for transcriptional autoregulation and noncoding RNA termination.
Emma C Goguen, David A Brow

Genetics· August 2023

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Yeast U6 snRNA made by RNA polymerase II is less stable but functional.
Karli A Lipinski, Jing Chi, Xin Chen, Aaron A Hoskins, David A Brow

RNA· December 2022

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Human spliceosomal snRNA sequence variants generate variant spliceosomes.
Justin W Mabin, Peter W Lewis, David A Brow, Heidi Dvinge

RNA· October 2021

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Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes.
Eric J Montemayor, Johanna M Virta, Samuel M Hayes, Yuichiro Nomura, David A Brow

RNA· October 2020

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An Allosteric Network for Spliceosome Activation Revealed by High-Throughput Suppressor Analysis in .
David A Brow

Genetics· May 2019

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Regulation of a Eukaryotic Gene by GTP-Dependent Start Site Selection and Transcription Attenuation.
Jason N Kuehner, David A Brow

Mol Cell· May 2019

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Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA.
Eric J Montemayor, Allison L Didychuk, Allyson D Yake, Gurnimrat K Sidhu, David A Brow

Nat Commun· May 2018

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The life of U6 small nuclear RNA, from cradle to grave.
Allison L Didychuk, Samuel E Butcher, David A Brow

RNA· April 2018

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Usb1 controls U6 snRNP assembly through evolutionarily divergent cyclic phosphodiesterase activities.
Allison L Didychuk, Eric J Montemayor, Tucker J Carrocci, Andrew T DeLaitsch, Stefani E Lucarelli, David A Brow

Nat Commun· September 2017

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Transcriptomes of six mutants in the Sen1 pathway reveal combinatorial control of transcription termination across the Saccharomyces cerevisiae genome.
Xin Chen, Kunal Poorey, Melissa N Carver, Ulrika Müller, Stefan Bekiranov, David A Brow

PLoS Genet· June 2017

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Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core.
Eric J Montemayor, Allison L Didychuk, Honghong Liao, Panzhou Hu, David A Brow

Acta Crystallogr D Struct Biol· January 2017

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A multi-step model for facilitated unwinding of the yeast U4/U6 RNA duplex.
Margaret L Rodgers, Allison L Didychuk, Samuel E Butcher, David A Brow, Aaron A Hoskins

Nucleic Acids Res· December 2016

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Structural requirements for protein-catalyzed annealing of U4 and U6 RNAs during di-snRNP assembly.
Allison L Didychuk, Eric J Montemayor, David A Brow, Samuel E Butcher

Nucleic Acids Res· February 2016

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Saccharomyces cerevisiae Sen1 Helicase Domain Exhibits 5'- to 3'-Helicase Activity with a Preference for Translocation on DNA Rather than RNA.
Stephen Martin-Tumasz, David A Brow

J Biol Chem· September 2015

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Spliceosome assembly in the absence of stable U4/U6 RNA pairing.
Jordan E Burke, Samuel E Butcher, David A Brow

RNA· May 2015

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An RNA mystery and its denouement.
David A Brow

RNA· April 2015

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Saccharomyces cerevisiae Sen1 as a model for the study of mutations in human Senataxin that elicit cerebellar ataxia.
Xin Chen, Ulrika Müller, Kaitlin E Sundling, David A Brow

Genetics· October 2014

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Core structure of the U6 small nuclear ribonucleoprotein at 1.7-Å resolution.
Eric J Montemayor, Elizabeth C Curran, Hong Hong Liao, Kristie L Andrews, Christine N Treba, David A Brow

Nat Struct Mol Biol· June 2014

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An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8.
Argenta M Price, Janina Görnemann, Christine Guthrie, David A Brow

RNA· January 2014

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A novel occluded RNA recognition motif in Prp24 unwinds the U6 RNA internal stem loop.
Stephen Martin-Tumasz, Ashley C Richie, Lawrence J Clos, David A Brow, Samuel E Butcher

Nucleic Acids Res· September 2011

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Sen-sing RNA terminators.
David A Brow

Mol Cell· June 2011

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