Publications by authors named "David A Cheresh"

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Macrophage-Engaging IgG4 Antibody Triggers Cytotoxicity Against Integrin αvβ3+ Cancers.
Joshua P Reddy, Ziqi Yu, Ryan M Shepard, Tami Von Schalscha, Rebecca A Clague, David A Cheresh

Mol Cancer Ther· October 2025

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A STAT3/integrin axis accelerates pancreatic cancer initiation and progression.
Alejandro D Campos, Ryan M Shepard, Zachary Ortega, Ingrid Heumann, Anna E Wilke, David A Cheresh

Cell Rep· August 2025

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Targeting Pancreatic Cancer Cell Stemness by Blocking Fibronectin-Binding Integrins on Cancer-Associated Fibroblasts.
Chengsheng Wu, Tami Von Schalscha, Diva Sansanwal, Chen Qian, Qinlin Jiang, David A Cheresh

Cancer Res Commun· January 2025

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Tumor-initiating cells establish a niche to overcome isolation stress.
Chengsheng Wu, Sara M Weis, David A Cheresh

Trends Cell Biol· May 2024

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Integrin αvβ3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity.
Arin Nam, Shashi Jain, Chengsheng Wu, Alejandro Campos, Ryan M Shepard, David A Cheresh

Cancer Res· May 2024

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Targeting the αVβ3/NgR2 pathway in neuroendocrine prostate cancer.
Anna Testa, Fabio Quaglia, Nicole M Naranjo, Cecilia E Verrillo, Christopher D Shields, David A Cheresh

Matrix Biol· December 2023

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Upregulation of fibronectin and its integrin receptors - an adaptation to isolation stress that facilitates tumor initiation.
Chengsheng Wu, Sara M Weis, David A Cheresh

J Cell Sci· October 2023

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Pancreatic cancer cells upregulate LPAR4 in response to isolation stress to promote an ECM-enriched niche and support tumour initiation.
Chengsheng Wu, Taha Rakhshandehroo, Hiromi I Wettersten, Alejandro Campos, Tami von Schalscha, David A Cheresh

Nat Cell Biol· February 2023

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Metastasis is a highly stressful process.
Alejandro D Campos, Sara M Weis, David A Cheresh

Cancer Metastasis Rev· December 2020

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Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αβ Axis.
Zhe Zhu, Pinar Mesci, Jean A Bernatchez, Ryan C Gimple, Xiuxing Wang, David A Cheresh

Cell Stem Cell· February 2020

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Arming Tumor-Associated Macrophages to Reverse Epithelial Cancer Progression.
Hiromi I Wettersten, Sara M Weis, Paulina Pathria, Tami Von Schalscha, Toshiyuki Minami, David A Cheresh

Cancer Res· October 2019

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Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy.
Patrick Carlson, Arko Dasgupta, Candice A Grzelak, Jeanna Kim, Alexander Barrett, David A Cheresh

Nat Cell Biol· February 2019

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Integrin CD11b activation drives anti-tumor innate immunity.
Michael C Schmid, Samia Q Khan, Megan M Kaneda, Paulina Pathria, Ryan Shepard, David A Cheresh

Nat Commun· December 2018

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Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription.
Huawei Wang, John Lapek, Ken Fujimura, Jan Strnadel, Bei Liu, David A Cheresh

Cell Discov· May 2018

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Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis.
Qi Sun, Jacqueline Lesperance, Hiromi Wettersten, Elaine Luterstein, Yoko S DeRose, David A Cheresh

J Clin Invest· January 2018

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Re-thinking the preclinical development of GBM therapeutics.
Érika Cosset, Sara M Weis, David A Cheresh

Oncoscience· January 2018

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Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers.
Laetitia Seguin, Maria F Camargo, Hiromi I Wettersten, Shumei Kato, Jay S Desgrosellier, David A Cheresh

Cancer Discov· December 2017

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Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma.
Érika Cosset, Sten Ilmjärv, Valérie Dutoit, Kathryn Elliott, Tami von Schalscha, David A Cheresh

Cancer Cell· December 2017

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Treatment of rats with the JAK-2 inhibitor fedratinib does not lead to experimental Wernicke's encephalopathy.
Alan S Hazell, Szeifoul Afadlal, David A Cheresh, Ashraf Azar

Neurosci Lett· March 2017

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MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment.
RaeAnna Wilson, Cristina Espinosa-Diez, Nathan Kanner, Namita Chatterjee, Rebecca Ruhl, David A Cheresh

Nat Commun· November 2016

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Glioblastomas require integrin αvβ3/PAK4 signaling to escape senescence.
Aleksandra Franovic, Kathryn C Elliott, Laetitia Seguin, M Fernanda Camargo, Sara M Weis, David A Cheresh

Cancer Res· November 2015

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Kinase-independent role for CRAF-driving tumour radioresistance via CHK2.
Sunil J Advani, Maria Fernanda Camargo, Laetitia Seguin, Ainhoa Mielgo, Sudarshan Anand, David A Cheresh

Nat Commun· September 2015

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hESC Differentiation toward an Autonomic Neuronal Cell Fate Depends on Distinct Cues from the Co-Patterning Vasculature.
Lisette M Acevedo, Jeffrey N Lindquist, Breda M Walsh, Peik Sia, Flavio Cimadamore, David A Cheresh

Stem Cell Reports· June 2015

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Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance.
Laetitia Seguin, Jay S Desgrosellier, Sara M Weis, David A Cheresh

Trends Cell Biol· April 2015

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Integrin αvβ3 drives slug activation and stemness in the pregnant and neoplastic mammary gland.
Jay S Desgrosellier, Jacqueline Lesperance, Laetitia Seguin, Maricel Gozo, Shumei Kato, David A Cheresh

Dev Cell· August 2014

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