Publications by authors named "David A Kass"

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Modeling HFpEF in animals.
David A Kass

Nat Cardiovasc Res· December 2025

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Rationale and Design of the HeartShare/AMP-HF Deep Phenotyping Study to Improve Understanding of Heart Failure With Preserved Ejection Fraction.
Barry A Borlaug, Julio A Chirinos, Gregory D Lewis, Margaret M Redfield, Alain G Bertoni, David A Kass

JACC Heart Fail· December 2025

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Congestion and Low Cardiac Output Hemodynamic Phenotype Drives Outcomes in Overweight and Obese HFpEF.
Vivek P Jani, Joban Vaishnav, Soumya Vungarala, Virginia S Hahn, Danielle Hopkins, David A Kass

JACC Heart Fail· November 2025

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Macrophages lacking TSC2 have mTORC1-dependent increased GPNMB and ameliorate ventricular dysfunction/remodeling after ischemia-reperfusion.
Mohammad Keykhaei, Navid Koleini, Mariam Meddeb, David J Polhemus, Masih Tajdini, David A Kass

Sci Rep· November 2025

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Desmoglein-2 deficiency results in cardiac dysfunction by compromising both Z-disc- and intercalated disc-mediated mechanotransduction.
Maicon Landim-Vieira, Vivek P Jani, Emily Shiel, Hosna Rastegarpouyani, Morgan Engel, David A Kass

bioRxiv· October 2025

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To Loop or Not to Loop? Why and How Cardiac Invasive Pressure-Volume Relations Remain Important.
David A Kass

Circulation· August 2025

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What can skinned cardiomyocytes teach us about heart disease? Response to letter to the editor: Challenges in assessing myoflament calcium sensitivity and contractile function in HFpEF by Christophe Maack and Vasco Sequeira.
Vivek Jani, David A Kass

J Mol Cell Cardiol· July 2025

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ATP-Citrate Lyase Supports Cardiac Function and NAD/NADH Balance and Is Depressed in Human Failing Myocardium.
Mariam Meddeb, Navid Koleini, Mohammad Keykhaei, Ting Liu, Marcus Rhodehamel, David A Kass

JACC Basic Transl Sci· July 2025

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Macrophages Lacking TSC2 have mTORC1-dependent GPNMB Augmentation Ameliorating Cardiac Ischemia-Reperfusion Injury.
Mohammad Keykhaei, Navid Koleini, Mariam Meddeb, Masih Tajdini, Malihe Rezaee, David A Kass

bioRxiv· June 2025

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Cyclic nucleotide phosphodiesterases as drug targets.
Michy P Kelly, Viacheslav O Nikolaev, Leila Gobejishvili, Claire Lugnier, Christian Hesslinger, David A Kass

Pharmacol Rev· May 2025

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Myocardial Proteome in Human Heart Failure With Preserved Ejection Fraction.
Vivek P Jani, Edwin J Yoo, Aleksandra Binek, Alina Guo, Julie S Kim, David A Kass

J Am Heart Assoc· March 2025

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Single cell transcriptomic analyses of human heart failure with preserved ejection fraction.
Virginia Shalkey Hahn, Mark Chaffin, Bridget Simonson, Sydney Jenkin, Abigail S Mulligan, David A Kass

bioRxiv· March 2025

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Cardiac cGMP Regulation and Therapeutic Applications.
Sumita Mishra, Vivek Chander, David A Kass

Hypertension· February 2025

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Phosphodiesterases: Evolving Concepts and Implications for Human Therapeutics.
Evan D Kelly, Mark J Ranek, Manling Zhang, David A Kass, Grace K Muller

Annu Rev Pharmacol Toxicol· January 2025

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Assessing and interpreting diastolic function in animal models of heart disease.
David A Kass

J Mol Cell Cardiol· December 2024

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Cardiomyocyte myofilament function in common animal models of heart failure with preserved ejection fraction.
Vivek P Jani, Navid Koleini, Axel J Fenwick, Thomas E Sharp, Traci T Goodchild, David A Kass

J Mol Cell Cardiol· December 2024

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Landscape of glycolytic metabolites and their regulating proteins in myocardium from human heart failure with preserved ejection fraction.
Navid Koleini, Mariam Meddeb, Liang Zhao, Mohammad Keykhaei, Seoyoung Kwon, David A Kass

Eur J Heart Fail· September 2024

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Myocardial ultrastructure of human heart failure with preserved ejection fraction.
Mariam Meddeb, Navid Koleini, Aleksandra Binek, Mohammad Keykhaei, Reyhane Darehgazani, David A Kass

Nat Cardiovasc Res· August 2024

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Relationship Between Myocardial NPPB Expression and Serum NT-proBNP in Heart Failure With Preserved Ejection Fraction.
Virginia S Hahn, Hildur Knutsdottir, Tess E Peterson, Daniel Kikuchi, Soumya Vungarala, David A Kass

JACC Heart Fail· July 2024

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ATP Citrate Lyase Supports Cardiac Function and NAD+/NADH Balance And Is Depressed in Human Heart Failure.
Mariam Meddeb, Navid Koleini, Seungho Jun, Mohammad Keykhaei, Farnaz Farshidfar, David A Kass

bioRxiv· June 2024

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Benchmarking pre-clinical heart failure with preserved ejection fraction models: can we do better?
David A Kass

Cardiovasc Res· May 2024

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The structural OFF and ON states of myosin can be decoupled from the biochemical super- and disordered-relaxed states.
Vivek P Jani, Taejeong Song, Chengqian Gao, Henry Gong, Sakthivel Sadayappan, David A Kass

PNAS Nexus· February 2024

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Common Heart Failure With Preserved Ejection Fraction Animal Models Yield Disparate Myofibril Mechanics.
Axel J Fenwick, Vivek P Jani, D Brian Foster, Thomas E Sharp, Traci T Goodchild, David A Kass

J Am Heart Assoc· January 2024

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Depressed Proximal Glycolysis in Myocardium Of Human Heart Failure with Preserved Ejection Fraction.
Navid Koleini, Mariam Meddeb, Mohammad Keykhaei, Seoyoung Kwon, Liang Zhao, David A Kass

medRxiv· October 2023

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The structural OFF and ON states of myosin can be decoupled from the biochemical super-relaxed and disordered-relaxed states.
Weikang Ma, Vivek P Jani, Taejeong Song, Chengqian Gao, Henry Gong, David A Kass

bioRxiv· October 2023

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