Publications by authors named "David Arnott"

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Targeted degradation via direct 26S proteasome recruitment.
Charlene Bashore, Sumit Prakash, Matthew C Johnson, Ryan J Conrad, Ivy A Kekessie, David Arnott

Nat Chem Biol· January 2023

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Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity.
Rosa Barreira da Silva, Ricardo M Leitao, Ximo Pechuan-Jorge, Scott Werneke, Jason Oeh, David Arnott

Nat Immunol· April 2022

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Caroline A. Evans, Phillip C. Wright, Josselin Noirel (Eds.): Mass spectrometry of proteins: methods and protocols.
David Arnott

Anal Bioanal Chem· June 2020

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Proteomic Analyses Identify a Novel Role for EZH2 in the Initiation of Cancer Cell Drug Tolerance.
Victoria Pham, Robert Pitti, Charles A Tindell, Tommy K Cheung, Alexandre Masselot, David Arnott

J Proteome Res· April 2020

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Regulation of Tumor-Associated Myeloid Cell Activity by CBP/EP300 Bromodomain Modulation of H3K27 Acetylation.
Denise E de Almeida Nagata, Eugene Y Chiang, Suchit Jhunjhunwala, Patrick Caplazi, Vidhyalakshmi Arumugam, David Arnott

Cell Rep· April 2019

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Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.
Ryan Raisner, Samir Kharbanda, Lingyan Jin, Edwin Jeng, Emily Chan, David Arnott

Cell Rep· August 2018

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Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes.
Teresita L Arenzana, Steve Lianoglou, Akiko Seki, Celine Eidenschenk, Tommy Cheung, David Arnott

Sci Immunol· April 2018

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A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2'-Deoxycytidine.
Benjamin R Leadem, Ioannis Kagiampakis, Catherine Wilson, Tommy K Cheung, David Arnott

Cancer Res· March 2018

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SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer.
Manuel Viotti, Catherine Wilson, Mark McCleland, Hartmut Koeppen, Benjamin Haley, David Arnott

J Cell Biol· February 2018

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Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia.
Trinna L Cuellar, Anna-Maria Herzner, Xiaotian Zhang, Yogesh Goyal, Colin Watanabe, David Arnott

J Cell Biol· November 2017

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Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure.
Gulfem Dilek Guler, Charles Albert Tindell, Robert Pitti, Catherine Wilson, Katrina Nichols, David Arnott

Cancer Cell· August 2017

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An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition.
Brian Egan, Chih-Chi Yuan, Madeleine Lisa Craske, Paul Labhart, Gulfem D Guler, David Arnott

PLoS One· June 2017

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Quantitative Proteomics Reveals Fundamental Regulatory Differences in Oncogenic HRAS and Isocitrate Dehydrogenase (IDH1) Driven Astrocytoma.
Sophia Doll, Anatoly Urisman, Juan A Oses-Prieto, David Arnott, Alma L Burlingame

Mol Cell Proteomics· January 2017

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A Putative Bacterial ABC Transporter Circumvents the Essentiality of Signal Peptidase.
J Hiroshi Morisaki, Peter A Smith, Shailesh V Date, Kimberly K Kajihara, Chau Linda Truong, David Arnott

mBio· September 2016

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An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells.
Maia Vinogradova, Victor S Gehling, Amy Gustafson, Shilpi Arora, Charles A Tindell, David Arnott

Nat Chem Biol· July 2016

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Phosphoproteome analysis of the MAPK pathway reveals previously undetected feedback mechanisms.
Florian Gnad, Sophia Doll, Kyung Song, Matthew P Stokes, John Moffat, David Arnott

Proteomics· July 2016

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Quantitative phosphoproteomic analysis of the PI3K-regulated signaling network.
Florian Gnad, Jeffrey Wallin, Kyle Edgar, Sophia Doll, David Arnott

Proteomics· July 2016

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NLRP3 recruitment by NLRC4 during Salmonella infection.
Yan Qu, Shahram Misaghi, Kim Newton, Allie Maltzman, Anita Izrael-Tomasevic, David Arnott

J Exp Med· May 2016

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Bioinformatics analysis of thousands of TCGA tumors to determine the involvement of epigenetic regulators in human cancer.
Florian Gnad, Sophia Doll, Gerard Manning, David Arnott, Zemin Zhang

BMC Genomics· March 2016

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Evolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains.
Travis W Bainbridge, Venita I DeAlmeida, Anita Izrael-Tomasevic, Cécile Chalouni, Borlan Pan, David Arnott

PLoS One· November 2015

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Mass spectrometric quantification of histone post-translational modifications by a hybrid chemical labeling method.
Tobias M Maile, Anita Izrael-Tomasevic, Tommy Cheung, Gulfem D Guler, Charles Tindell, David Arnott

Mol Cell Proteomics· April 2015

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Metabolic and transcriptional profiling reveals pyruvate dehydrogenase kinase 4 as a mediator of epithelial-mesenchymal transition and drug resistance in tumor cells.
Yuting Sun, Anneleen Daemen, Georgia Hatzivassiliou, David Arnott, Catherine Wilson

Cancer Metab· November 2014

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Stable-isotope-labeled histone peptide library for histone post-translational modification and variant quantification by mass spectrometry.
Shu Lin, Samuel Wein, Michelle Gonzales-Cope, Gabriel L Otte, Zuo-Fei Yuan, David Arnott

Mol Cell Proteomics· September 2014

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Identification of longitudinally dynamic biomarkers in Alzheimer's disease cerebrospinal fluid by targeted proteomics.
Kristin R Wildsmith, Stephen P Schauer, Ashley M Smith, David Arnott, Yuda Zhu

Mol Neurodegener· June 2014

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Identifying potential therapeutic targets of methicillin-resistant Staphylococcus aureus through in vivo proteomic analysis.
Binh An Diep, Qui Phung, Shailesh Date, David Arnott, Corey Bakalarski

J Infect Dis· May 2014

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