Publications by authors named "Shilpi Arora"

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Enhanced transdermal delivery of curcuminoids from statistically designed nano-emulgel formulated using Eucalyptus oil.
Shilpi Arora, Deepak Kaushik, Mohammad Akhlaquer Rahman, Rohit Dutt, Abhishek Tiwari

Ther Deliv· July 2025

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Brillouin-assisted generation and demultiplexing of widely tunable high-repetition rate 1064 nm optical frequency combs with applications in spectral beam combining.
Soubhik Pal, Shilpi Arora, Sarthak Dash, C G Lakshmi, V R Supradeepa

Opt Express· May 2025

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Comprehensive Target Engagement by the EZH2 Inhibitor Tulmimetostat Allows for Targeting of ARID1A Mutant Cancers.
Patricia J Keller, Elizabeth J Adams, Rentian Wu, Alexandre Côté, Shilpi Arora

Cancer Res· August 2024

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Identification and characterization of second-generation EZH2 inhibitors with extended residence times and improved biological activity.
Jacob I Stuckey, Nico R Cantone, Alexandre Côté, Shilpi Arora, Valerie Vivat

J Biol Chem· August 2021

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Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening.
Esther C Y Lee, Andrew J McRiner, Katy E Georgiadis, Julie Liu, Zooey Wang, Shilpi Arora

J Med Chem· May 2021

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Bispecific Estrogen Receptor α Degraders Incorporating Novel Binders Identified Using DNA-Encoded Chemical Library Screening.
Jeremy S Disch, Jennifer M Duffy, Esther C Y Lee, Diana Gikunju, Betty Chan, Shilpi Arora

J Med Chem· April 2021

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Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time.
Avinash Khanna, Alexandre Côté, Shilpi Arora, Ludivine Moine, Victor S Gehling

ACS Med Chem Lett· June 2020

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Data Analysis for High-Throughput RNAi Screening.
David O Azorsa, Megan A Turnidge, Shilpi Arora

Methods Mol Biol· December 2017

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Identification of potent, selective KDM5 inhibitors.
Victor S Gehling, Steven F Bellon, Jean-Christophe Harmange, Yves LeBlanc, Florence Poy, Shilpi Arora

Bioorg Med Chem Lett· September 2016

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An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells.
Maia Vinogradova, Victor S Gehling, Amy Gustafson, Shilpi Arora, Charles A Tindell

Nat Chem Biol· July 2016

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Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes.
John P McGrath, Kaylyn E Williamson, Srividya Balasubramanian, Shobu Odate, Shilpi Arora

Cancer Res· April 2016

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EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation.
William D Bradley, Shilpi Arora, Jennifer Busby, Srividya Balasubramanian, Victor S Gehling

Chem Biol· November 2014

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Clonal evolution of a case of treatment refractory maxillary sinus carcinoma.
Shilpi Arora, Ronald L Korn, Elizabeth Lenkiewicz, Irene Cherni, Thomas G Beach

PLoS One· March 2013

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Paired tumor and normal whole genome sequencing of metastatic olfactory neuroblastoma.
Glen J Weiss, Winnie S Liang, Tyler Izatt, Shilpi Arora, Irene Cherni

PLoS One· October 2012

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Foxo3a drives proliferation in anaplastic thyroid carcinoma through transcriptional regulation of cyclin A1: a paradigm shift that impacts current therapeutic strategies.
Laura A Marlow, Christina A von Roemeling, Simon J Cooper, Yilin Zhang, Stephen D Rohl, Shilpi Arora

J Cell Sci· September 2012

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Hedgehog signaling pathway molecules and ALDH1A1 expression in early-stage non-small cell lung cancer.
Guy Raz, Kristi E Allen, Chris Kingsley, Irene Cherni, Shilpi Arora

Lung Cancer· May 2012

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RNAi screening of the kinome with cytarabine in leukemias.
Raoul Tibes, James M Bogenberger, Leena Chaudhuri, R Tanner Hagelstrom, Donald Chow, Shilpi Arora

Blood· March 2012

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MicroRNA-328 is associated with (non-small) cell lung cancer (NSCLC) brain metastasis and mediates NSCLC migration.
Shilpi Arora, Aarati R Ranade, Nhan L Tran, Sara Nasser, Shravan Sridhar

Int J Cancer· December 2011

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High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells.
Meredith C Henderson, Irma M Gonzales, Shilpi Arora, Ashish Choudhary, Jeffrey M Trent

Mol Cancer Res· June 2011

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RNAi-based functional pharmacogenomics.
Sukru Tuzmen, Pinar Tuzmen, Shilpi Arora, Spyro Mousses, David Azorsa

Methods Mol Biol· April 2011

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NCI60 cancer cell line panel data and RNAi analysis help identify EAF2 as a modulator of simvastatin and lovastatin response in HCT-116 cells.
Sevtap Savas, David O Azorsa, Hamdi Jarjanazi, Irada Ibrahim-Zada, Irma M Gonzales, Shilpi Arora

PLoS One· April 2011

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Detailed molecular fingerprinting of four new anaplastic thyroid carcinoma cell lines and their use for verification of RhoB as a molecular therapeutic target.
Laura A Marlow, Jaclyn D'Innocenzi, Yilin Zhang, Stephen D Rohl, Simon J Cooper, Shilpi Arora

J Clin Endocrinol Metab· December 2010

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RNAi screening of the kinome identifies modulators of cisplatin response in ovarian cancer cells.
Shilpi Arora, Kristen M Bisanz, Lourdes A Peralta, Gargi D Basu, Ashish Choudhary

Gynecol Oncol· September 2010

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RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma.
Shilpi Arora, Irma M Gonzales, R Tanner Hagelstrom, Christian Beaudry, Ashish Choudhary

Mol Cancer· August 2010

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A high-content RNAi-screening assay to identify modulators of cholesterol accumulation in Niemann-Pick type C cells.
Shilpi Arora, Christian Beaudry, Kristen M Bisanz, Chao Sima, Jeffrey A Kiefer

Assay Drug Dev Technol· June 2010

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