Publications by authors named "David Barros"

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Enteral glutamine for trauma patients in intensive care unit - Comment on: ESPEN practical and partially revised guideline: Clinical nutrition in the intensive care unit.
Artur Barbosa Gomes, David de Sousa Cortez Barros, Ana Beatriz Gonçalves Portela Alves de Sousa, Lara Rafaela Alves Dos Santos

Clin Nutr· June 2024

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Cyclic AMP-Mediated Inhibition of Cholesterol Catabolism in by the Novel Drug Candidate GSK2556286.
Kirstin L Brown, Kaley M Wilburn, Christine R Montague, Jason C Grigg, Olalla Sanz, David Barros

Antimicrob Agents Chemother· January 2023

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GSK2556286 Is a Novel Antitubercular Drug Candidate Effective with the Potential To Shorten Tuberculosis Treatment.
Eric L Nuermberger, Maria Santos Martínez-Martínez, Olalla Sanz, Beatriz Urones, Jorge Esquivias, David Barros

Antimicrob Agents Chemother· June 2022

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Tres Cantos Open Lab: celebrating a decade of innovation in collaboration to combat endemic infectious diseases.
Felix Calderón, Lluis Ballell, David Barros, Graeme Bilbe, Nicholas Cammack

Nat Rev Drug Discov· November 2021

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Redescription and DNA barcoding of diurnal moth Athroolopha latimargo
Rothschild, 1914 bona sp., stat. rev. from the southern Iberian Peninsula (Lepidoptera: Geometridae: Ennominae).
Juan J Guerrero, E David Cuenca, David Barros, Antonio S Ortiz

Zootaxa· January 2020

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Obstructive sleep apnea and dyslipidemia: from animal models to clinical evidence.
David Barros, Francisco García-Río

Sleep· March 2019

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Identification and Profiling of Hydantoins-A Novel Class of Potent Antimycobacterial DprE1 Inhibitors.
Maciej K Rogacki, Eleni Pitta, Olga Balabon, Sophie Huss, Eva Maria Lopez-Roman, David Barros

J Med Chem· December 2018

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HIV infection, high-risk behaviors and substance use in homeless men sheltered in therapeutic communities in Central Brazil.
Sandra M Brunini, Cleiciane V de Lima Barros, Rafael Alves Guimarães, Hélio Galdino Júnior, Giovanni Rezza, David A Costa Barros

Int J STD AIDS· November 2018

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Bio-behavioral survey of syphilis in homeless men in Central Brazil: a cross-sectional study.
Cleiciane Vieira de Lima Barros, Hélio Galdino Júnior, Giovanni Rezza, Rafael Alves Guimarães, Priscilla Martins Ferreira, David Antônio Costa Barros

Cad Saude Publica· June 2018

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Screening of a Novel Fragment Library with Functional Complexity against Mycobacterium tuberculosis InhA.
Federica Prati, Fabio Zuccotto, Daniel Fletcher, Maire A Convery, Raquel Fernandez-Menendez, David Barros

ChemMedChem· April 2018

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Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656).
Xianfeng Li, Vincent Hernandez, Fernando L Rock, Wai Choi, Yvonne S L Mak, David Barros

J Med Chem· October 2017

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Target Identification of Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach.
Grace Mugumbate, Vitor Mendes, Michal Blaszczyk, Mohamad Sabbah, George Papadatos, David Barros

Front Pharmacol· September 2017

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Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface.
Katherine A Abrahams, Jonathan A G Cox, Klaus Fütterer, Joaquín Rullas, Fátima Ortega-Muro, David Barros

Sci Rep· August 2017

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A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors.
Marta Esposito, Sára Szadocka, Giulia Degiacomi, Beatrice S Orena, Giorgia Mori, David Barros

ACS Infect Dis· June 2017

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Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen.
Jonathan A G Cox, Grace Mugumbate, Laura Vela-Glez Del Peral, Monika Jankute, Katherine A Abrahams, David Barros

Sci Rep· December 2016

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Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase.
Andrés Palencia, Xianfeng Li, Wei Bu, Wai Choi, Charles Z Ding, David Barros

Antimicrob Agents Chemother· October 2016

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Identification of KasA as the cellular target of an anti-tubercular scaffold.
Katherine A Abrahams, Chun-Wa Chung, Sonja Ghidelli-Disse, Joaquín Rullas, María José Rebollo-López, David Barros

Nat Commun· September 2016

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Repurposing clinically approved cephalosporins for tuberculosis therapy.
Santiago Ramón-García, Rubén González Del Río, Angel Santos Villarejo, Gaye D Sweet, Fraser Cunningham, David Barros

Sci Rep· September 2016

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Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor.
María Martínez-Hoyos, Esther Perez-Herran, Gulcin Gulten, Lourdes Encinas, Daniel Álvarez-Gómez, David Barros

EBioMedicine· June 2016

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New direct inhibitors of InhA with antimycobacterial activity based on a tetrahydropyran scaffold.
Stane Pajk, Matej Živec, Roman Šink, Izidor Sosič, Margarete Neu, David Barros

Eur J Med Chem· April 2016

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Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation.
Grace Mugumbate, Katherine A Abrahams, Jonathan A G Cox, George Papadatos, Gerard van Westen, David Barros

PLoS One· February 2016

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THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria.
Jonathan A G Cox, Katherine A Abrahams, Carlos Alemparte, Sonja Ghidelli-Disse, Joaquín Rullas, David Barros

Nat Microbiol· January 2016

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Hydrolysis of clavulanate by Mycobacterium tuberculosis β-lactamase BlaC harboring a canonical SDN motif.
Daria Soroka, Inès Li de la Sierra-Gallay, Vincent Dubée, Sébastien Triboulet, Herman van Tilbeurgh, David Barros

Antimicrob Agents Chemother· September 2015

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Mycobacterium tuberculosis gyrase inhibitors as a new class of antitubercular drugs.
Delia Blanco, Esther Perez-Herran, Mónica Cacho, Lluís Ballell, Julia Castro, David Barros

Antimicrob Agents Chemother· April 2015

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Design, synthesis, and evaluation of new thiadiazole-based direct inhibitors of enoyl acyl carrier protein reductase (InhA) for the treatment of tuberculosis.
Roman Šink, Izidor Sosič, Matej Živec, Raquel Fernandez-Menendez, Samo Turk, David Barros

J Med Chem· January 2015

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