Publications by authors named "David Brafman"

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Serum amyloid P (PTX2) attenuates hepatic fibrosis in mice by inhibiting the activation of fibrocytes and HSCs.
Min Cong, Raquel Carvalho Gontijo Weber, Sadatsugu Sakane, Vivian Zhang, Chunyan Jiang, David Brafman

Hepatol Commun· November 2024

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PINE-TREE enables highly efficient genetic modification of human cell lines.
Carlye Frisch, William W Kostes, Brooke Galyon, Brycelyn Whitman, Stefan J Tekel, David A Brafman

Mol Ther Nucleic Acids· September 2023

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Traumatic brain injury induces TDP-43 mislocalization and neurodegenerative effects in tissue distal to the primary injury site in a non-transgenic mouse.
George R Bjorklund, Jennifer Wong, David Brafman, Robert Bowser, Sarah E Stabenfeldt

Acta Neuropathol Commun· August 2023

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The Multifaceted Role of WNT Signaling in Alzheimer's Disease Onset and Age-Related Progression.
William W Kostes, David A Brafman

Cells· April 2023

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Modeling long QT syndrome type 2 on-a-chip via in-depth assessment of isogenic gene-edited 3D cardiac tissues.
Jaimeson Veldhuizen, Helen F Mann, Nina Karamanova, Wade D Van Horn, Raymond Q Migrino, David Brafman

Sci Adv· December 2022

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A microcarrier-based protocol for scalable generation and purification of human induced pluripotent stem cell-derived neurons and astrocytes.
Jacob Knittel, Gayathri Srinivasan, Carlye Frisch, Nicholas Brookhouser, Sreedevi Raman, David A Brafman

STAR Protoc· September 2022

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The Emergence of Model Systems to Investigate the Link Between Traumatic Brain Injury and Alzheimer's Disease.
Gayathri Srinivasan, David A Brafman

Front Aging Neurosci· February 2022

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Correction to: Apolipoprotein E regulates lipid metabolism and α‑synuclein pathology in human iPSC‑derived cerebral organoids.
Jing Zhao, Wenyan Lu, Yingxue Ren, Yuan Fu, Yuka A Martens, David A Brafman

Acta Neuropathol· January 2022

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Generation of 3X FLAG-tagged human embryonic stem cell (hESC) line to study WNT-induced β-catenin DNA interactions (HVRDe009-A-2).
Joshua Cutts, Warner Kostes, David A Brafman

Stem Cell Res· December 2021

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Weighing up the evidence used by direct-to-consumer stem cell businesses.
Margaret Cook, Alexandra Richey, David A Brafman, Emma K Frow

Stem Cell Reports· December 2021

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Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids.
Jing Zhao, Wenyan Lu, Yingxue Ren, Yuan Fu, Yuka A Martens, David A Brafman

Acta Neuropathol· November 2021

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APOE2 mitigates disease-related phenotypes in an isogenic hiPSC-based model of Alzheimer's disease.
Nicholas Brookhouser, Sreedevi Raman, Carlye Frisch, Gayathri Srinivasan, David A Brafman

Mol Psychiatry· October 2021

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Cytosine and adenosine base editing in human pluripotent stem cells using transient reporters for editing enrichment.
Stefan J Tekel, Nicholas Brookhouser, Kylie Standage-Beier, Xiao Wang, David A Brafman

Nat Protoc· July 2021

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Author Correction: APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids.
Jing Zhao, Yuan Fu, Yu Yamazaki, Yingxue Ren, Mary D Davis, David A Brafman

Nat Commun· May 2021

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Prime Editing Guide RNA Design Automation Using PINE-CONE.
Kylie Standage-Beier, Stefan J Tekel, David A Brafman, Xiao Wang

ACS Synth Biol· February 2021

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Guidelines for establishing a 3-D printing biofabrication laboratory.
Henry W Sanicola, Caleb E Stewart, Michael Mueller, Farzad Ahmadi, Dadong Wang, David A Brafman

Biotechnol Adv· December 2020

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A Cas9-mediated adenosine transient reporter enables enrichment of ABE-targeted cells.
Nicholas Brookhouser, Toan Nguyen, Stefan J Tekel, Kylie Standage-Beier, Xiao Wang, David A Brafman

BMC Biol· December 2020

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APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids.
Jing Zhao, Yuan Fu, Yu Yamazaki, Yingxue Ren, Mary D Davis, David A Brafman

Nat Commun· November 2020

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Engineering anisotropic human stem cell-derived three-dimensional cardiac tissue on-a-chip.
Jaimeson Veldhuizen, Joshua Cutts, David A Brafman, Raymond Q Migrino, Mehdi Nikkhah

Biomaterials· October 2020

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Human Autopsy-Derived Scalp Fibroblast Biobanking for Age-Related Neurodegenerative Disease Research.
Suet Theng Beh, Carlye Frisch, David A Brafman, Jared Churko, Jessica E Walker

Cells· October 2020

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A Defined and Scalable Peptide-Based Platform for the Generation of Human Pluripotent Stem Cell-Derived Astrocytes.
Sreedevi Raman, Gayathri Srinivasan, Nicholas Brookhouser, Toan Nguyen, Tanner Henson, David A Brafman

ACS Biomater Sci Eng· June 2020

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Using human induced pluripotent stem cells (hiPSCs) to investigate the mechanisms by which Apolipoprotein E (APOE) contributes to Alzheimer's disease (AD) risk.
Sreedevi Raman, Nicholas Brookhouser, David A Brafman

Neurobiol Dis· May 2020

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A transient reporter for editing enrichment (TREE) in human cells.
Kylie Standage-Beier, Stefan J Tekel, Nicholas Brookhouser, Grace Schwarz, Toan Nguyen, David A Brafman

Nucleic Acids Res· February 2020

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BIG-TREE: Base-Edited Isogenic hPSC Line Generation Using a Transient Reporter for Editing Enrichment.
Nicholas Brookhouser, Stefan J Tekel, Kylie Standage-Beier, Toan Nguyen, Grace Schwarz, David A Brafman

Stem Cell Reports· February 2020

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RNA-Guided Recombinase-Cas9 Fusion Targets Genomic DNA Deletion and Integration.
Kylie Standage-Beier, Nicholas Brookhouser, Parithi Balachandran, Qi Zhang, David A Brafman

CRISPR J· August 2019

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