Publications by authors named "David Breault"

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CXXC Finger Protein 1 drives BMP signaling and progenitor cell differentiation during limb development.
Emanuele Pignatti, Lijie Jiang, Manasvi S Shah, Anish Karpurapu, Ji Miao, David T Breault

Dev Biol· December 2025

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Primary Small Intestinal Epithelia Are Physiological Alternatives to the Caco-2 Lymphatic Transport Model.
Ian M Smith, Oljora Rezhdo, Meihui Pan, Mitesh Patel, Nichola Smith, David T Breault

Mol Pharm· December 2025

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Abrogation of FGFR signaling blocks β-catenin-induced adrenocortical hyperplasia and aldosterone production.
Vasileios Chortis, Dulanjalee Kariyawasam, Mesut Berber, Nick A Guagliardo, Sining Leng, David T Breault

JCI Insight· November 2025

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Osmolarity Controls Oscillatory Calcium Signaling to Reduce Autonomous Aldosterone Production in Zona Glomerulosa Cells.
Mohamed Diagne, Molly R Gerding, David T Breault, Edward H Nieh, Mark P Beenhakker

Endocrinology· November 2025

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Rho-ROCK signaling and α-Catenin mediate β-Catenin-driven hyperplasia in the adrenal via adherens junctions.
Mesut Berber, Betul Haykir, Nick A Guagliardo, Vasileios Chortis, Kleiton Silva Borges, David T Breault

bioRxiv· October 2025

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Discovery of a radiation countermeasure therapeutic for intestinal injury enabled by human organ chips combined with AI.
Alican Özkan, Gwenn Merry, Joshua Piatok, Arash Naziripour, Nina LoGrande, David Breault

medRxiv· October 2025

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Glutamine antagonism suppresses tumor growth in adrenocortical carcinoma through inhibition of de novo nucleotide biosynthesis.
Vasileios Chortis, Kleiton Silva Borges, Cong-Hui Yao, Claudio Ribeiro, Luis Fernando Nagano, David T Breault

bioRxiv· September 2025

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Loss of WNT2B Increases Progression from Dysplasia to Colorectal Cancer.
Luiz Fernando Silva Oliveira, Yu-Syuan Wu, Sathuwarman Raveenthiraraj, Jaedeok Kwon, Venkata Siva Dasuri, David T Breault

bioRxiv· August 2025

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Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma.
Katia Mariniello, James F H Pittaway, Barbara Altieri, Kleiton Silva Borges, Irene Hadjidemetriou, David T Breault

Cancer Commun (Lond)· June 2025

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Human mesofluidic intestinal model for studying transport of drug carriers and bacteria through a live mucosal barrier.
Chia-Ming Wang, Hardeep S Oberoi, Devalina Law, Yuan Li, Timothy Kassis, David T Breault

Lab Chip· June 2025

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Mesenchymal WNT2B is required for the development and function of the human intestine.
Akaljot Singh, Holly M Poling, Jennifer Foulke-Abel, Nambirajan Sundaram, Abid A Reza, David T Breault

bioRxiv· May 2025

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Hippo Signaling Is Essential for the Maintenance of Zona Glomerulosa Cell Fate in the Murine Adrenal Cortex.
Nour Abou Nader, Natalia Jakuc, Marie-Charlotte Meinsohn, Laureline Charrier, Laurence Banville, David T Breault

Endocrinology· April 2025

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The transcription factor HHEX maintains glucocorticoid levels and protects adrenals from androgen-induced lipid depletion.
Typhanie Dumontet, Kaitlin J Basham, Micah C Foster, Emma Silverman, Kyle A Heard, David T Breault

Res Sq· April 2025

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Clonal memory of colitis accumulates and promotes tumor growth.
Jason Buenrostro, Surya Nagaraja, Lety Ojeda-Miron, Ruochi Zhang, Ena Oreskovic, David Breault

Res Sq· March 2025

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RELMβ sets the threshold for microbiome-dependent oral tolerance.
Emmanuel Stephen-Victor, Gavin A Kuziel, Monica Martinez-Blanco, Bat-Erdene Jugder, Mehdi Benamar, David T Breault

Nature· February 2025

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Clonal memory of colitis accumulates and promotes tumor growth.
Surya Nagaraja, Lety Ojeda-Miron, Ruochi Zhang, Ena Oreskovic, Yan Hu, David T Breault

bioRxiv· February 2025

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Cataloguing the postnatal small intestinal transcriptome during the first postnatal month.
Luiz Fernando Silva Oliveira, Radhika S Khetani, Yu-Syuan Wu, Venkata Siva Dasuri, Amanda W Harrington, David T Breault

bioRxiv· December 2024

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Human Mesofluidic Intestinal Model for Studying Transport of Drug Carriers and Bacteria Through a Live Mucosal Barrier.
Chia-Ming Wang, Hardeep S Oberoi, Devalina Law, Yuan Li, Timothy Kassis, David T Breault

bioRxiv· September 2024

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Pathogenic variants in KMT2C result in a neurodevelopmental disorder distinct from Kleefstra and Kabuki syndromes.
Dmitrijs Rots, Sanaa Choufani, Victor Faundes, Alexander J M Dingemans, Shelagh Joss, David Breault

Am J Hum Genet· August 2024

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Gut tumors in flies alter the taste valence of an anti-tumorigenic bitter compound.
Nicole Y Leung, Chiwei Xu, Joshua Shing Shun Li, Anindya Ganguly, Geoff T Meyerhof, David T Breault

Curr Biol· August 2024

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Response to Letter to the Editor From Hoekstra: "Adrenal Abcg1 Controls Cholesterol Flux and Steroidogenesis".
David T Breault, Christa E Flück, Emanuele Pignatti

Endocrinology· August 2024

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Non-canonical Wnt signaling triggered by WNT2B drives adrenal aldosterone production.
Kleiton S Borges, Donald W Little, Taciani de Almeida Magalhães, Claudio Ribeiro, Typhanie Dumontet, David T Breault

bioRxiv· August 2024

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Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma.
Katia Mariniello, James F H Pittaway, Barbara Altieri, Kleiton Silva Borges, Irene Hadjidemetriou, David T Breault

bioRxiv· August 2024

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Gut tumors in flies alter the taste valence of an anti-tumorigenic bitter compound.
Nicole Y Leung, Chiwei Xu, Joshua Shing Shun Li, Anindya Ganguly, Geoff T Meyerhof, David T Breault

Curr Biol· June 2024

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A2-165 metabolizes host- and media-derived chemicals and induces transcriptional changes in colonic epithelium in GuMI human gut microphysiological system.
Yu-Ja Huang, Caroline A Lewis, Charles Wright, Kirsten Schneider, John Kemmitt, David T Breault

Microbiome Res Rep· May 2024

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