Publications by authors named "Jason Buenrostro"

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Adrenergic signaling coordinates distant and local responses to amputation in axolotl.
Duygu Payzin-Dogru, Tim Froitzheim, Steven J Blair, Siddhartha G Jena, Hani Singer, Jason D Buenrostro

Cell· December 2025

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scooby: modeling multimodal genomic profiles from DNA sequence at single-cell resolution.
Johannes C Hingerl, Laura D Martens, Alexander Karollus, Trevor Manz, Jason D Buenrostro

Nat Methods· November 2025

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Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours.
Samarth Hegde, Bruno Giotti, Brian Y Soong, Laszlo Halasz, Jessica Le Berichel, Jason D Buenrostro

Nature· October 2025

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Coupling CRISPR scanning with targeted chromatin accessibility profiling using a double-stranded DNA deaminase.
Heejin Roh, Simon P Shen, Yan Hu, Hui Si Kwok, Allison P Siegenfeld, Jason D Buenrostro

Nat Methods· October 2025

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Reprogramming Factors Activate a Non-Canonical Oxidative Resilience Pathway That Can Rejuvenate RPEs and Restore Vision.
Yuancheng Ryan Lu, James C Cameron, Yan Hu, Han Shen, Shintaro Shirahama, Jason D Buenrostro

bioRxiv· September 2025

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Engineered histones reshape chromatin in human cells.
Siddhartha G Jena, Surya Nagaraja, Andrew S Earl, Amalia R Driller-Colangelo, Michael A Quezada, Jason D Buenrostro

bioRxiv· September 2025

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scooby: Modeling multi-modal genomic profiles from DNA sequence at single-cell resolution.
Johannes C Hingerl, Laura D Martens, Alexander Karollus, Trevor Manz, Jason D Buenrostro

bioRxiv· July 2025

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Refining sequence-to-activity models by increasing model resolution.
Nuria Alina Chandra, Yan Hu, Jason D Buenrostro, Sara Mostafavi, Alexander Sasse

bioRxiv· July 2025

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Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation.
Ajay S Labade, Zachary D Chiang, Caroline Comenho, Paul L Reginato, Andrew C Payne, Jason D Buenrostro

Science· July 2025

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The Somatic Mosaicism across Human Tissues Network.
Tim H H Coorens, Ji Won Oh, Yujin Angelina Choi, Nam Seop Lim, Boxun Zhao, Jason D Buenrostro

Nature· July 2025

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Adrenergic signaling coordinates distant and local responses to amputation in axolotl.
Duygu Payzin-Dogru, Tim Froitzheim, Steven J Blair, Siddhartha G Jena, Hani Singer, Jason D Buenrostro

bioRxiv· July 2025

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HBO1 functions as an epigenetic barrier to hepatocyte plasticity and reprogramming during liver injury.
Wei-Chien Yuan, Andrew S Earl, Sai Ma, Karel Alcedo, Jacquelyn O Russell, Jason D Buenrostro

Cell Stem Cell· June 2025

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Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma.
Lindsay M LaFave, Vinay K Kartha, Sai Ma, Kevin Meli, Isabella Del Priore, Jason D Buenrostro

Cancer Cell· May 2025

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Invigorating discovery and clinical translation of aging biomarkers.
Erik Jacques, Chiara Herzog, Kejun Ying, Alan Tomusiak, Jessica Kasamoto, Jason D Buenrostro

Nat Aging· April 2025

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Unified molecular approach for spatial epigenome, transcriptome, and cell lineages.
Yung-Hsin Huang, Julia A Belk, Ruochi Zhang, Natasha E Weiser, Zachary Chiang, Jason D Buenrostro

Proc Natl Acad Sci U S A· April 2025

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Clonal memory of colitis accumulates and promotes tumor growth.
Jason Buenrostro, Surya Nagaraja, Lety Ojeda-Miron, Ruochi Zhang, Ena Oreskovic

Res Sq· March 2025

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Multiscale footprints reveal the organization of cis-regulatory elements.
Yan Hu, Max A Horlbeck, Ruochi Zhang, Sai Ma, Rojesh Shrestha, Jason D Buenrostro

Nature· February 2025

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Multi-locus CRISPRi targeting with a single truncated guide RNA.
Molly M Moore, Siddarth Wekhande, Robbyn Issner, Alejandro Collins, Anna J Cruz, Jason D Buenrostro

Nat Commun· February 2025

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Clonal memory of colitis accumulates and promotes tumor growth.
Surya Nagaraja, Lety Ojeda-Miron, Ruochi Zhang, Ena Oreskovic, Yan Hu, Jason D Buenrostro

bioRxiv· February 2025

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Degradation of IKZF1 prevents epigenetic progression of T cell exhaustion in an antigen-specific assay.
Tristan Tay, Gayathri Bommakanti, Elizabeth Jaensch, Aparna Gorthi, Iswarya Karapa Reddy, Jason Daniel Buenrostro

Cell Rep Med· November 2024

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Expansion genome sequencing links nuclear abnormalities to hotspots of aberrant euchromatin repression.
Ajay S Labade, Zachary D Chiang, Caroline Comenho, Paul L Reginato, Andrew C Payne, Jason D Buenrostro

bioRxiv· September 2024

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BACH2 regulates diversification of regulatory and proinflammatory chromatin states in T17 cells.
Pratiksha I Thakore, Alexandra Schnell, Linglin Huang, Maryann Zhao, Yu Hou, Jason D Buenrostro

Nat Immunol· August 2024

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A transcription factor atlas of directed differentiation.
Julia Joung, Sai Ma, Tristan Tay, Kathryn R Geiger-Schuller, Paul C Kirchgatterer, Jason D Buenrostro

Cell· June 2024

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Cell of origin epigenetic priming determines susceptibility to Tet2 mutation.
Giulia Schiroli, Vinay Kartha, Fabiana M Duarte, Trine A Kristiansen, Christina Mayerhofer, Jason D Buenrostro

Nat Commun· May 2024

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Author Correction: Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling.
Caleb A Lareau, Leif S Ludwig, Christoph Muus, Satyen H Gohil, Tongtong Zhao, Jason D Buenrostro

Nat Biotechnol· September 2023

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