Publications by authors named "Max A Horlbeck"

Claim this Profile
E
Engineered histones reshape chromatin in human cells.
Siddhartha G Jena, Surya Nagaraja, Andrew S Earl, Amalia R Driller-Colangelo, Michael A Quezada, Max A Horlbeck

bioRxiv· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel Phenotypes and Genotype-Phenotype Correlations in a Large Clinical Cohort of Patients With Kleefstra Syndrome.
Zoë J Frazier, Seyda Kilic, Hailey Osika, Alisa Mo, Meg Quinn, Max A Horlbeck

Clin Genet· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy.
Shruti Menon, Daniel Gracilla, Marcus R Breese, Yone Phar Lin, Filemon Dela Cruz, Max A Horlbeck

bioRxiv· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multiscale footprints reveal the organization of cis-regulatory elements.
Yan Hu, Max A Horlbeck, Ruochi Zhang, Sai Ma, Rojesh Shrestha

Nature· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CRISPRi screens identify the lncRNA, , as a multifunctional locus regulating macrophage differentiation and inflammatory signaling.
Haley Halasz, Eric Malekos, Sergio Covarrubias, Samira Yitiz, Christy Montano, Max A Horlbeck

Proc Natl Acad Sci U S A· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
FET fusion oncoproteins disrupt physiologic DNA repair networks and induce ATR synthetic lethality in cancer.
Shruti Menon, Marcus R Breese, Yone Phar Lin, Hannah Allegakoen, Shruthi Perati, Max A Horlbeck

Res Sq· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
GATOR2-dependent mTORC1 activity is a therapeutic vulnerability in FOXO1 fusion-positive rhabdomyosarcoma.
Jacqueline Morales, David V Allegakoen, José A Garcia, Kristen Kwong, Pushpendra K Sahu, Max A Horlbeck

JCI Insight· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dual genome-wide coding and lncRNA screens in neural induction of induced pluripotent stem cells.
David Wu, Aunoy Poddar, Elpiniki Ninou, Elizabeth Hwang, Mitchel A Cole, Max A Horlbeck

Cell Genom· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.
Maxence Le Vasseur, Jonathan Friedman, Marco Jost, Jiawei Xu, Justin Yamada, Max A Horlbeck

Elife· May 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genome-Scale Perturbation of Long Noncoding RNA Expression Using CRISPR Interference.
S John Liu, Max A Horlbeck, Jonathan S Weissman, Daniel A Lim

Methods Mol Biol· March 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High-content imaging-based pooled CRISPR screens in mammalian cells.
Xiaowei Yan, Nico Stuurman, Susana A Ribeiro, Marvin E Tanenbaum, Max A Horlbeck

J Cell Biol· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent.
Marco Jost, Yuwen Chen, Luke A Gilbert, Max A Horlbeck, Lenno Krenning

Mol Cell· July 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fitness effects of CRISPR/Cas9-targeting of long noncoding RNA genes.
Max A Horlbeck, S John Liu, Howard Y Chang, Daniel A Lim, Jonathan S Weissman

Nat Biotechnol· May 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs.
Marco Jost, Daniel A Santos, Reuben A Saunders, Max A Horlbeck, John S Hawkins

Nat Biotechnol· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma.
S John Liu, Martina Malatesta, Brian V Lien, Parna Saha, Shivani S Thombare, Max A Horlbeck

Genome Biol· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Exploring genetic interaction manifolds constructed from rich single-cell phenotypes.
Thomas M Norman, Max A Horlbeck, Joseph M Replogle, Alex Y Ge, Albert Xu

Science· August 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cellular response to small molecules that selectively stall protein synthesis by the ribosome.
Nadège Liaud, Max A Horlbeck, Luke A Gilbert, Ketrin Gjoni, Jonathan S Weissman

PLoS Genet· March 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform.
Kirk J Wangensteen, Yue J Wang, Zhixun Dou, Amber W Wang, Elham Mosleh-Shirazi, Max A Horlbeck

Hepatology· August 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mapping the Genetic Landscape of Human Cells.
Max A Horlbeck, Albert Xu, Min Wang, Neal K Bennett, Chong Y Park

Cell· August 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure.
Bryce A Mendelsohn, Neal K Bennett, Maxwell A Darch, Katharine Yu, Mai K Nguyen, Max A Horlbeck

PLoS Biol· August 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element.
Seung Woo Cho, Jin Xu, Ruping Sun, Maxwell R Mumbach, Ava C Carter, Max A Horlbeck

Cell· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates.
Zhou Yu, Lauren E Surface, Chong Yon Park, Max A Horlbeck, Gregory A Wyant

Elife· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting RAS-driven human cancer cells with antibodies to upregulated and essential cell-surface proteins.
Alexander J Martinko, Charles Truillet, Olivier Julien, Juan E Diaz, Max A Horlbeck

Elife· January 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent.
Marco Jost, Yuwen Chen, Luke A Gilbert, Max A Horlbeck, Lenno Krenning

Mol Cell· October 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response.
Britt Adamson, Thomas M Norman, Marco Jost, Min Y Cho, James K Nuñez, Max A Horlbeck

Cell· December 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis