Publications by authors named "Joseph M Replogle"

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Transcriptome-wide analysis of differential expression in perturbation atlases.
Ajay Nadig, Joseph M Replogle, Angela N Pogson, Mukundh Murthy, Steven A McCarroll

Nat Genet· May 2025

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Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress.
Brian T Do, Peggy P Hsu, Sidney Y Vermeulen, Zhishan Wang, Taghreed Hirz, Joseph M Replogle

Dev Cell· August 2024

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Transcriptome-wide characterization of genetic perturbations.
Ajay Nadig, Joseph M Replogle, Angela N Pogson, Steven A McCarroll, Jonathan S Weissman

bioRxiv· July 2024

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Microfluidics-free single-cell genomics with templated emulsification.
Iain C Clark, Kristina M Fontanez, Robert H Meltzer, Yi Xue, Corey Hayford, Joseph M Replogle

Nat Biotechnol· November 2023

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Author Correction: Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning.
Luke W Koblan, Mandana Arbab, Max W Shen, Jeffrey A Hussmann, Andrew V Anzalone, Joseph M Replogle

Nat Biotechnol· November 2023

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Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq.
Sara Sunshine, Andreas S Puschnik, Joseph M Replogle, Matthew T Laurie, Jamin Liu

Nat Commun· October 2023

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A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens.
Alina Guna, Katharine R Page, Joseph M Replogle, Theodore K Esantsi, Maxine L Wang

BMC Genomics· October 2023

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A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens.
Alina Guna, Katharine R Page, Joseph M Replogle, Theodore K Esantsi, Maxine L Wang

bioRxiv· August 2023

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Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors.
Joseph M Replogle, Jessica L Bonnar, Angela N Pogson, Christina R Liem, Nolan K Maier

Elife· December 2022

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Dual genome-wide coding and lncRNA screens in neural induction of induced pluripotent stem cells.
David Wu, Aunoy Poddar, Elpiniki Ninou, Elizabeth Hwang, Mitchel A Cole, Joseph M Replogle

Cell Genom· November 2022

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MTCH2 is a mitochondrial outer membrane protein insertase.
Alina Guna, Taylor A Stevens, Alison J Inglis, Joseph M Replogle, Theodore K Esantsi

Science· October 2022

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Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.
Joseph M Replogle, Reuben A Saunders, Angela N Pogson, Jeffrey A Hussmann, Alexander Lenail

Cell· July 2022

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Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution.
Dian Yang, Matthew G Jones, Santiago Naranjo, William M Rideout, Kyung Hoi Joseph Min, Joseph M Replogle

Cell· May 2022

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Mapping transcriptomic vector fields of single cells.
Xiaojie Qiu, Yan Zhang, Jorge D Martin-Rufino, Chen Weng, Shayan Hosseinzadeh, Joseph M Replogle

Cell· February 2022

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Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning.
Luke W Koblan, Mandana Arbab, Max W Shen, Jeffrey A Hussmann, Andrew V Anzalone, Joseph M Replogle

Nat Biotechnol· November 2021

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Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.
James K Nuñez, Jin Chen, Greg C Pommier, J Zachery Cogan, Joseph M Replogle

Cell· April 2021

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Rapid deployment of SARS-CoV-2 testing: The CLIAHUB.
Emily D Crawford, Irene Acosta, Vida Ahyong, Erika C Anderson, Shaun Arevalo, Joseph M Replogle

PLoS Pathog· October 2020

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GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control.
Kelsey L Hickey, Kimberley Dickson, J Zachery Cogan, Joseph M Replogle, Michael Schoof

Mol Cell· September 2020

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Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing.
Joseph M Replogle, Thomas M Norman, Albert Xu, Jeffrey A Hussmann, Jin Chen

Nat Biotechnol· August 2020

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Exploring genetic interaction manifolds constructed from rich single-cell phenotypes.
Thomas M Norman, Max A Horlbeck, Joseph M Replogle, Alex Y Ge, Albert Xu

Science· August 2019

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A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.
Katie J Ryan, Charles C White, Kruti Patel, Jishu Xu, Marta Olah, Joseph M Replogle

Sci Transl Med· December 2017

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Genetic architecture of age-related cognitive decline in African Americans.
Towfique Raj, Lori B Chibnik, Cristin McCabe, Andus Wong, Joseph M Replogle

Neurol Genet· February 2017

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Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci.
Gail Chan, Charles C White, Phoebe A Winn, Maria Cimpean, Joseph M Replogle

Neurol Genet· August 2016

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Nucleosomes impede Cas9 access to DNA in vivo and in vitro.
Max A Horlbeck, Lea B Witkowsky, Benjamin Guglielmi, Joseph M Replogle, Luke A Gilbert

Elife· March 2016

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Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4+ T cells.
William Orent, Allison R Mchenry, Deepak A Rao, Charles White, Hans-Ulrich Klein, Joseph M Replogle

Hum Mol Genet· January 2016

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