Publications by authors named "Reuben A Saunders"

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High-resolution spatial mapping of cell state and lineage dynamics in vivo with PEtracer.
Luke W Koblan, Kathryn E Yost, Pu Zheng, William N Colgan, Matthew G Jones, Reuben A Saunders

Science· October 2025

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Perturb-Multimodal: A platform for pooled genetic screens with imaging and sequencing in intact mammalian tissue.
Reuben A Saunders, William E Allen, Xingjie Pan, Jaspreet Sandhu, Jiaqi Lu

Cell· August 2025

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High-resolution spatial mapping of cell state and lineage dynamics with PEtracer.
Luke W Koblan, Kathryn E Yost, Pu Zheng, William N Colgan, Matthew G Jones, Reuben A Saunders

bioRxiv· June 2025

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A platform for multimodal pooled genetic screens reveals regulators of liver function.
Reuben A Saunders, William E Allen, Xingjie Pan, Jaspreet Sandhu, Jiaqi Lu

bioRxiv· February 2025

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Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology.
Gayathri Muthukumar, Taylor A Stevens, Alison J Inglis, Theodore K Esantsi, Reuben A Saunders

Mol Cell· March 2024

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Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology.
Gayathri Muthukumar, Taylor A Stevens, Alison J Inglis, Theodore K Esantsi, Reuben A Saunders

bioRxiv· August 2023

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Comparative landscape of genetic dependencies in human and chimpanzee stem cells.
Richard She, Tyler Fair, Nathan K Schaefer, Reuben A Saunders, Bryan J Pavlovic

Cell· July 2023

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Comparative landscape of genetic dependencies in human and chimpanzee stem cells.
Richard She, Tyler Fair, Nathan K Schaefer, Reuben A Saunders, Bryan J Pavlovic

bioRxiv· March 2023

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Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs.
Michael R Das, Yeonji Chang, Rachel Anderson, Reuben A Saunders, Nan Zhang

Proc Natl Acad Sci U S A· January 2023

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Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.
Joseph M Replogle, Reuben A Saunders, Angela N Pogson, Jeffrey A Hussmann, Alexander Lenail

Cell· July 2022

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An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Michael Schoof, Bryan Faust, Reuben A Saunders, Smriti Sangwan, Veronica Rezelj

Science· December 2020

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Multistep substrate binding and engagement by the AAA+ ClpXP protease.
Reuben A Saunders, Benjamin M Stinson, Tania A Baker, Robert T Sauer

Proc Natl Acad Sci U S A· November 2020

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An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation.
Michael Schoof, Bryan Faust, Reuben A Saunders, Smriti Sangwan, Veronica Rezelj

bioRxiv· August 2020

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Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs.
Marco Jost, Daniel A Santos, Reuben A Saunders, Max A Horlbeck, John S Hawkins

Nat Biotechnol· March 2020

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A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response.
Niko Amin-Wetzel, Reuben A Saunders, Maarten J Kamphuis, Claudia Rato, Steffen Preissler

Cell· December 2017

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Porous titanium bases for osteochondral tissue engineering.
Adam B Nover, Stephanie L Lee, Maria S Georgescu, Daniel R Howard, Reuben A Saunders

Acta Biomater· November 2015

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