Publications by authors named "David Critchley"

Claim this Profile
P
Pharmacokinetic Drug-Drug Interaction With Coadministration of Cannabidiol and Everolimus in a Phase 1 Healthy Volunteer Trial.
Louise Wray, Joris Berwaerts, David Critchley, Kerry Hyland, Cuiping Chen

Clin Pharmacol Drug Dev· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Tensin3 interaction with talin drives the formation of fibronectin-associated fibrillar adhesions.
Paul Atherton, Rafaella Konstantinou, Suat Peng Neo, Emily Wang, Eleonora Balloi, David Critchley

J Cell Biol· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Phase 1 Open-Label, Fixed-Sequence Pharmacokinetic Drug Interaction Trial to Investigate the Effect of Cannabidiol on the CYP1A2 Probe Caffeine in Healthy Subjects.
Ching Thai, Bola Tayo, David Critchley

Clin Pharmacol Drug Dev· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Clinical implications of trials investigating drug-drug interactions between cannabidiol and enzyme inducers or inhibitors or common antiseizure drugs.
Philip N Patsalos, Jerzy P Szaflarski, Barry Gidal, Kevan VanLandingham, David Critchley

Epilepsia· September 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Phase II Randomized Trial to Explore the Potential for Pharmacokinetic Drug-Drug Interactions with Stiripentol or Valproate when Combined with Cannabidiol in Patients with Epilepsy.
Elinor Ben-Menachem, Boudewijn Gunning, Carmen María Arenas Cabrera, Kevan VanLandingham, Julie Crockett, David Critchley

CNS Drugs· June 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A phase 1, randomized, pharmacokinetic trial of the effect of different meal compositions, whole milk, and alcohol on cannabidiol exposure and safety in healthy subjects.
Julie Crockett, David Critchley, Bola Tayo, Joris Berwaerts, Gilmour Morrison

Epilepsia· February 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Relief of talin autoinhibition triggers a force-independent association with vinculin.
Paul Atherton, Franziska Lausecker, Alexandre Carisey, Andrew Gilmore, David Critchley

J Cell Biol· January 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development.
Sijo Mathew, Riya J Palamuttam, Glenda Mernaugh, Harini Ramalingam, Zhenwei Lu, David R Critchley

Development· November 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Loss of mouse cardiomyocyte talin-1 and talin-2 leads to β-1 integrin reduction, costameric instability, and dilated cardiomyopathy.
Ana Maria Manso, Hideshi Okada, Francesca M Sakamoto, Emily Moreno, Susan J Monkley, David R Critchley

Proc Natl Acad Sci U S A· July 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex.
Thomas Zacharchenko, Xiaolan Qian, Benjamin T Goult, Devina Jethwa, Teresa B Almeida, David R Critchley

Structure· July 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Metabolite profiling of the multiple tyrosine kinase inhibitor lenvatinib: a cross-species comparison.
Anne-Charlotte Dubbelman, Cynthia M Nijenhuis, Robert S Jansen, Hilde Rosing, Hitoshi Mizuo, David Critchley

Invest New Drugs· June 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Safety and pharmacokinetic profile of rufinamide in pediatric patients aged less than 4 years with Lennox-Gastaut syndrome: An interim analysis from a multicenter, randomized, active-controlled, open-label study.
Alexis Arzimanoglou, Jose A Ferreira, Andrew Satlin, Shannon Mendes, Betsy Williams, David Critchley

Eur J Paediatr Neurol· May 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
Vinculin controls talin engagement with the actomyosin machinery.
Paul Atherton, Ben Stutchbury, De-Yao Wang, Devina Jethwa, Ricky Tsang, David R Critchley

Nat Commun· December 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Talin determines the nanoscale architecture of focal adhesions.
Jaron Liu, Yilin Wang, Wah Ing Goh, Honzhen Goh, Michelle A Baird, David R Critchley

Proc Natl Acad Sci U S A· September 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Ligand-Occupied Integrin Internalization Links Nutrient Signaling to Invasive Migration.
Elena Rainero, Jonathan D Howe, Patrick T Caswell, Nigel B Jamieson, Kurt Anderson, David R Critchley

Cell Rep· January 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.
Xuefei Tian, Jin Ju Kim, Susan M Monkley, Nanami Gotoh, Ramiro Nandez, David R Critchley

J Clin Invest· March 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation.
Benjamin T Goult, Xiao-Ping Xu, Alexandre R Gingras, Mark Swift, Bipin Patel, David R Critchley

J Struct Biol· October 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Talins and kindlins: partners in integrin-mediated adhesion.
David A Calderwood, Iain D Campbell, David R Critchley

Nat Rev Mol Cell Biol· August 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
Benjamin T Goult, Thomas Zacharchenko, Neil Bate, Ricky Tsang, Fiona Hey, David R Critchley

J Biol Chem· March 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Talin1 and Rap1 are critical for osteoclast function.
Wei Zou, Takashi Izawa, Tingting Zhu, Jean Chappel, Karel Otero, David R Critchley

Mol Cell Biol· February 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.
Ana Maria Manso, Ruixia Li, Susan J Monkley, Nathalia M Cruz, Shannon Ong, David R Critchley

J Biol Chem· February 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile.
Emmanuel Debrand, Francesco J Conti, Neil Bate, Lorraine Spence, Daniela Mazzeo, David R Critchley

Biochem Biophys Res Commun· September 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics.
Neil Bate, Alexandre R Gingras, Alexia Bachir, Rick Horwitz, Feng Ye, David R Critchley

PLoS One· August 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation.
Craig T Lefort, Jan Rossaint, Markus Moser, Brian G Petrich, Alexander Zarbock, David R Critchley

Blood· May 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Subcellular localization of talin is regulated by inter-domain interactions.
Asoka Banno, Benjamin T Goult, HoSup Lee, Neil Bate, David R Critchley

J Biol Chem· April 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis