Publications by authors named "David Demedts"

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Assembly of γ-secretase occurs through stable dimers after exit from the endoplasmic reticulum.
Rosanne Wouters, Christine Michiels, Ragna Sannerud, Bertrand Kleizen, Katleen Dillen, David Demedts

J Cell Biol· September 2021

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Superparamagnetic Nanoparticles for Lysosome Isolation to Identify Spatial Alterations in Lysosomal Protein and Lipid Composition.
Arun Kumar Tharkeshwar, David Demedts, Wim Annaert

STAR Protoc· December 2020

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BACE1 levels correlate with phospho-tau levels in human cerebrospinal fluid.
Soraia Barao, Lujia Zhou, Katarzyna Adamczuk, Tine Vanhoutvin, Fred van Leuven, David Demedts

Curr Alzheimer Res· September 2013

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Glycogen synthase kinase-3β (GSK3β) expression in a mouse model of Alzheimer's disease: a light and electron microscopy study.
Johanna C Gandy, Miguel Melendez-Ferro, Gautam N Bijur, Fred Van Leuven, Joy K Roche, David Demedts

Synapse· June 2013

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Identification of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase-3α.
Fabio Lo Monte, Thomas Kramer, Jiamin Gu, Upendra Rao Anumala, Luciana Marinelli, David Demedts

J Med Chem· May 2012

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GSK-3α/β kinases and amyloid production in vivo.
Tomasz Jaworski, Ilse Dewachter, Benoit Lechat, Maarten Gees, Anna Kremer, David Demedts

Nature· December 2011

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Early improved and late defective cognition is reflected by dendritic spines in Tau.P301L mice.
Anna Kremer, Hervé Maurin, David Demedts, Herman Devijver, Peter Borghgraef

J Neurosci· December 2011

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Dendritic degeneration, neurovascular defects, and inflammation precede neuronal loss in a mouse model for tau-mediated neurodegeneration.
Tomasz Jaworski, Benoit Lechat, David Demedts, Lies Gielis, Herman Devijver

Am J Pathol· October 2011

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Amyloid precursor protein mutation E682K at the alternative β-secretase cleavage β'-site increases Aβ generation.
Lujia Zhou, Nathalie Brouwers, Iryna Benilova, Annelies Vandersteen, Marc Mercken, David Demedts

EMBO Mol Med· May 2011

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AAV-tau mediates pyramidal neurodegeneration by cell-cycle re-entry without neurofibrillary tangle formation in wild-type mice.
Tomasz Jaworski, Ilse Dewachter, Benoit Lechat, Sophie Croes, Annelies Termont, David Demedts

PLoS One· October 2009

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