Publications by authors named "David Drewry"

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NUAK2 is a therapeutically tractable regulator of RNA splicing and tumor progression in neuroendocrine prostate cancer.
Umar Mehraj, Uran Maimekov, Shaista Manzoor, Emily Cordova, Manasiben Patel, David H Drewry

bioRxiv· November 2025

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A soft-stiff patterned bioengineering model reveals kinase pathways driving directional cell migration in pulmonary arterial hypertension.
Tamanna Islam, Jacob Hooper, Xiaojun Zhang, Clarissa Garcia, Md Mahedi Hasan, David H Drewry

Biomater Sci· October 2025

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NEK Family Kinases: Structure, Function, and Role in Disease.
Brandon M Baker, Julia R Boehling, Sarah Knopf, Stephanie Held, Margarite Matossian, David H Drewry

Biomolecules· October 2025

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Cellular Selectivity Analyses Reveal Distinguishing Profiles for Type II Kinase Inhibitors.
Matthew J Binder, Frances M Bashore, Kaitlin K Dunn Hoffman, Cameron Daamgard, Michael R Slater, David H Drewry

bioRxiv· October 2025

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NUAK kinases: Signaling mechanisms and therapeutic applications.
Nicole M Cullen, Peter Rosston, Bakhtawar Tufail, Anne E D'Armond, Ayushi Patel, David H Drewry

J Biol Chem· September 2025

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Structure-activity Relationship for Diarylpyrazoles as Inhibitors of the Fungal Kinase Yck2.
David J Shirley, Bonnie Yiu, Ikeer Mancera-Ortiz, Peter J Stogios, Zhongle Liu, David H Drewry

bioRxiv· July 2025

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Concurrent Inhibition of the RAS-MAPK Pathway and PIKfyve Is a Therapeutic Strategy for Pancreatic Cancer.
Jonathan M DeLiberty, Mallory K Roach, Clint A Stalnecker, Ryan Robb, Elyse G Schechter, David H Drewry

Cancer Res· April 2025

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Chemoproteomic Profiling of for Characterization of Antifungal Kinase Inhibitors.
David J Shirley, Meganathan Nandakumar, Aurora Cabrera, Bonnie Yiu, Emily Puumala, David H Drewry

J Med Chem· April 2025

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Convergence on CaMK4: A Key Modulator of Autism-Associated Signaling Pathways in Neurons.
Jacqueline Kaiser, Alana Risteska, Abbey G Muller, Haoxiong Sun, Bethany Lei, David H Drewry

Biol Psychiatry· March 2025

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Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapy.
Joseph A Newman, Angeline E Gavard, Nergis Imprachim, Hazel Aitkenhead, Hadley E Sheppard, David H Drewry

Nat Commun· February 2025

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Screening of a kinase inhibitor library identified novel targetable kinase pathways in triple-negative breast cancer.
Caroline H Rinderle, Christopher V Baker, Courtney B Lagarde, Khoa Nguyen, Sara Al-Ghadban, David H Drewry

Anticancer Drugs· January 2025

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Chemoproteomic Profiling of for Characterization of Anti-fungal Kinase Inhibitors.
David J Shirley, Meganathan Nandakumar, Aurora Cabrera, Bonnie Yiu, Emily Puumala, David H Drewry

bioRxiv· January 2025

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Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2.
Han Wee Ong, Xuan Yang, Jeffery L Smith, Sharon Taft-Benz, Stefanie Howell, David H Drewry

Molecules· September 2024

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Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2.
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, David H Drewry

ACS Med Chem Lett· August 2024

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More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication.
Han Wee Ong, Xuan Yang, Jeffery L Smith, Rebekah J Dickmander, Jason W Brown, David H Drewry

J Med Chem· July 2024

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Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships.
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, David H Drewry

Eur J Med Chem· May 2024

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Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2.
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle, David H Drewry

bioRxiv· May 2024

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Dynamic strain fields of the mouse brain during rotation.
Connor Bradfield, Liming Voo, David Drewry, Vassilis Koliatsos, K T Ramesh

Biomech Model Mechanobiol· April 2024

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Illumination of understudied ciliary kinases.
Raymond G Flax, Peter Rosston, Cecilia Rocha, Brian Anderson, Jacob L Capener, David H Drewry

Front Mol Biosci· March 2024

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Open Source Antibiotics: Simple Diarylimidazoles Are Potent against Methicillin-Resistant .
Dana M Klug, Edwin G Tse, Daniel G Silva, Yafeng Cao, Susan A Charman, David Drewry

ACS Infect Dis· December 2023

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Characterization of 2,4-Dianilinopyrimidines Against Five Kinases PfARK1, PfARK3, PfNEK3, PfPK9, and PfPKB.
Han Wee Ong, Chandi de Silva, Krisha Avalani, Frank Kwarcinski, Christopher R Mansfield, David H Drewry

ACS Med Chem Lett· December 2023

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Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships.
Christopher R M Asquith, Michael P East, Tuomo Laitinen, Carla Alamillo-Ferrer, Erkka Hartikainen, David H Drewry

bioRxiv· December 2023

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Fused Tetrahydroquinolines Are Interfering with Your Assay.
Frances M Bashore, Joel Annor-Gyamfi, Yuhong Du, Vittorio Katis, Felix Nwogbo, David H Drewry

J Med Chem· November 2023

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SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4.
Deanna Tiek, Carrow I Wells, Martin Schröder, Xiao Song, Carla Alamillo-Ferrer, David H Drewry

Curr Res Chem Biol· September 2023

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How many kinases are druggable? A review of our current understanding.
Brian Anderson, Peter Rosston, Han Wee Ong, Mohammad Anwar Hossain, Zachary W Davis-Gilbert, David H Drewry

Biochem J· August 2023

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