Publications by authors named "Frances M Bashore"

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Cellular Selectivity Analyses Reveal Distinguishing Profiles for Type II Kinase Inhibitors.
Matthew J Binder, Frances M Bashore, Kaitlin K Dunn Hoffman, Cameron Daamgard, Michael R Slater

bioRxiv· October 2025

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Development of a chemical probe to enable characterization of the casein kinase 1γ subfamily.
Jacob L Capener, Thomas W Kramer, Frances M Bashore, Emily Flory, Fengling Li

bioRxiv· September 2025

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BET degraders reveal BRD4 disruption of 7SK and P-TEFb is critical for effective reactivation of latent HIV in CD4+ T-cells.
Anne-Marie W Turner, Frances M Bashore, Shane D Falcinelli, Joshua A Fox, Alana L Keller

J Virol· April 2025

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Development of a Second-Generation, Chemical Probe for PIKfyve.
Sophia M Min, Frances M Bashore, Jeffery L Smith, Tammy M Havener, Stefanie Howell

J Med Chem· February 2025

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A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells.
Rachel McCole, James Nolan, David M Reck, Craig Monger, Samantha Rustichelli, Frances M Bashore

Cell Rep· January 2025

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Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2.
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle

ACS Med Chem Lett· August 2024

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Development of SYK NanoBRET Cellular Target Engagement Assays for Gain-of-Function Variants.
Jacob L Capener, James D Vasta, Vittorio L Katis, Ani Michaud, Michael T Beck, Frances M Bashore

bioRxiv· June 2024

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Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2.
Frances M Bashore, Sophia M Min, Xiangrong Chen, Stefanie Howell, Caroline H Rinderle

bioRxiv· May 2024

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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang

PLoS One· February 2024

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Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
Yuhong Du, William J Bradshaw, Tina M Leisner, Joel K Annor-Gyamfi, Kun Qian, Frances M Bashore

J Biol Chem· December 2023

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Fused Tetrahydroquinolines Are Interfering with Your Assay.
Frances M Bashore, Joel Annor-Gyamfi, Yuhong Du, Vittorio Katis, Felix Nwogbo

J Med Chem· November 2023

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Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology.
Anna Castano, Margaux Silvestre, Carrow I Wells, Jennifer L Sanderson, Carla A Ferrer, Frances M Bashore

Elife· July 2023

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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang

bioRxiv· July 2023

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Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology.
Anna Castano, Margaux Silvestre, Carrow I Wells, Jennifer L Sanderson, Carla A Ferrer, Frances M Bashore

bioRxiv· June 2023

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Development of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic strategy for Alzheimer's disease.
Yuhong Du, William J Bradshaw, Tina M Leisner, Joel K Annor-Gyamfi, Kun Qian, Frances M Bashore

bioRxiv· May 2023

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Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis.
Frances M Bashore, Ariana B Marquez, Apirat Chaikuad, Stefanie Howell, Andrea S Dunn

Sci Rep· April 2023

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Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2.
Zachary W Davis-Gilbert, Andreas Krämer, James E Dunford, Stefanie Howell, Filiz Senbabaoglu, Frances M Bashore

ACS Med Chem Lett· April 2023

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PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components.
Frances M Bashore, Caroline A Foley, Han Wee Ong, Justin M Rectenwald, Ronan P Hanley

ACS Chem Biol· March 2023

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