Publications by authors named "David Fear"

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CXCL13 as a Biomarker of Complex Common Variable Immunodeficiency.
Ioasaf Karafotias, Helene Martini, Charlotte V Lee, Terrence T J Hunter, Padmalal Gurugama, David Fear

J Clin Immunol· November 2025

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Inhibition of PI3K p110δ activity reduces IgE production in IL-4 and anti-CD40 stimulated human B cell cultures.
Anna Cutrina-Pons, Aloka De Sa, David J Fear, Hannah J Gould, Faruk Ramadani

Immunology· December 2023

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Extracellular vesicles in COVID-19 convalescence can regulate T cell metabolism and function.
Molly S George, Jenifer Sanchez, Christina Rollings, David Fear, Peter Irving

iScience· August 2023

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SARS-CoV-2-Specific Memory B Cell Responses Are Maintained After Recovery from Natural Infection and Postvaccination.
Tom Moore, Rojony Hossain, Katie J Doores, Manu Shankar-Hari, David J Fear

Viral Immunol· July 2022

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Quantitative assessment of NFκB transcription factor activity.
Terrence T J Hunter, David Fear, Paul Lavender, Jo Spencer, Mark Peakman

J Immunol Methods· May 2021

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Human marginal zone B cell development from early T2 progenitors.
Thomas J Tull, Michael J Pitcher, William Guesdon, Jacqueline H Y Siu, Cristina Lebrero-Fernández, David J Fear

J Exp Med· April 2021

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Serial magnetic resonance imaging findings during severe attacks of familial hemiplegic migraine type 2: a case report.
David Fear, Misha Patel, Ramin Zand

BMC Neurol· April 2021

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Altered chromatin landscape in circulating T follicular helper and regulatory cells following grass pollen subcutaneous and sublingual immunotherapy.
Hanisah Sharif, Swati Acharya, Gopal Krishna R Dhondalay, Gilda Varricchi, Shoshanna Krasner-Macleod, David J Fear

J Allergy Clin Immunol· February 2021

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Exosome-mediated RNAi of PAK4 prolongs survival of pancreatic cancer mouse model after loco-regional treatment.
Lizhou Xu, Farid N Faruqu, Yau M Lim, Kee Y Lim, Revadee Liam-Or, David Fear

Biomaterials· January 2021

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Transcriptional Analysis of the Human IgE-Expressing Plasma Cell Differentiation Pathway.
Faruk Ramadani, Holly Bowen, Hannah J Gould, David J Fear

Front Immunol· June 2020

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miR-29b directly targets activation-induced cytidine deaminase in human B cells and can limit its inappropriate expression in naïve B cells.
Timothy Recaldin, Philip S Hobson, Elizabeth H Mann, Faruk Ramadani, David J Cousins, David J Fear

Mol Immunol· September 2018

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Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue.
Yuan Zhao, Mohamed Uduman, Jacqueline H Y Siu, Thomas J Tull, Jeremy D Sanderson, David J Fear

Nat Commun· September 2018

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Activation-Associated Accelerated Apoptosis of Memory B Cells in Critically Ill Patients With Sepsis.
Manu Shankar-Hari, David Fear, Paul Lavender, Tracey Mare, Richard Beale

Crit Care Med· May 2017

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BET proteins are a key component of immunoglobulin gene expression.
Jung Min Shim, Jin S Lee, Kirsty E Russell, Coen H Wiegman, Peter J Barnes, David Fear

Epigenomics· April 2017

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Global gene regulation during activation of immunoglobulin class switching in human B cells.
Youming Zhang, David J Fear, Saffron A G Willis-Owen, William O Cookson, Miriam F Moffatt

Sci Rep· November 2016

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IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin.
Louise Saul, Kristina M Ilieva, Heather J Bax, Panagiotis Karagiannis, Isabel Correa, David J Fear

Sci Rep· July 2016

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Mechanisms regulating the targeting and activity of activation induced cytidine deaminase.
David J Fear

Curr Opin Immunol· October 2013

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Comprehensive FISH probe design tool applied to imaging human immunoglobulin class switch recombination.
Jakub Nedbal, Philip S Hobson, David J Fear, Rainer Heintzmann, Hannah J Gould

PLoS One· June 2013

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IgG4 subclass antibodies impair antitumor immunity in melanoma.
Panagiotis Karagiannis, Amy E Gilbert, Debra H Josephs, Niwa Ali, Tihomir Dodev, David J Fear

J Clin Invest· April 2013

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Soluble CD23 controls IgE synthesis and homeostasis in human B cells.
Alison M Cooper, Philip S Hobson, Mark R Jutton, Michael W Kao, Binia Drung, David J Fear

J Immunol· April 2012

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High resolution analysis of the chromatin landscape of the IgE switch region in human B cells.
Sandeep Dayal, Jakub Nedbal, Philip Hobson, Alison M Cooper, Hannah J Gould, David J Fear

PLoS One· February 2012

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Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locus.
Muslima Chowdhury, Omid Forouhi, Sandeep Dayal, Natalie McCloskey, Hannah J Gould, David J Fear

Proc Natl Acad Sci U S A· October 2008

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Gene expression subtypes in patients with chronic fatigue syndrome/myalgic encephalomyelitis.
Jonathan R Kerr, Robert Petty, Beverley Burke, John Gough, David Fear

J Infect Dis· April 2008

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IgE-antibody-dependent immunotherapy of solid tumors: cytotoxic and phagocytic mechanisms of eradication of ovarian cancer cells.
Sophia N Karagiannis, Marguerite G Bracher, James Hunt, Natalie McCloskey, Rebecca L Beavil, David J Fear

J Immunol· September 2007

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Soluble CD23 monomers inhibit and oligomers stimulate IGE synthesis in human B cells.
Natalie McCloskey, James Hunt, Rebecca L Beavil, Mark R Jutton, Gabrielle J Grundy, David J Fear

J Biol Chem· August 2007

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