Publications by authors named "David Filpula"

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A RNA antagonist of hypoxia-inducible factor-1alpha, EZN-2968, inhibits tumor cell growth.
Lee M Greenberger, Ivan D Horak, David Filpula, Puja Sapra, Majken Westergaard

Mol Cancer Ther· November 2008

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Releasable PEGylation of proteins with customized linkers.
David Filpula, Hong Zhao

Adv Drug Deliv Rev· January 2008

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Releasable PEGylation of mesothelin targeted immunotoxin SS1P achieves single dosage complete regression of a human carcinoma in mice.
David Filpula, Karen Yang, Amartya Basu, Raffit Hassan, Laiman Xiang

Bioconjug Chem· August 2007

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Antibody engineering and modification technologies.
David Filpula

Biomol Eng· June 2007

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Engineering an arginine catabolizing bioconjugate: Biochemical and pharmacological characterization of PEGylated derivatives of arginine deiminase from Mycoplasma arthritidis.
Maoliang Wang, Amartya Basu, Thomas Palm, Jack Hua, Stephen Youngster, David Filpula

Bioconjug Chem· January 2007

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A highly stable polyethylene glycol-conjugated human single-chain antibody neutralizing granulocyte-macrophage colony stimulating factor at low nanomolar concentration.
Eva-Maria Krinner, Julia Hepp, Patrick Hoffmann, Sandra Bruckmaier, Laetitia Petersen, David Filpula

Protein Eng Des Sel· October 2006

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Linear and branched bicin linkers for releasable PEGylation of macromolecules: controlled release in vivo and in vitro from mono- and multi-PEGylated proteins.
Hong Zhao, Karen Yang, Anthony Martinez, Amartya Basu, Ramesh Chintala, David Filpula

Bioconjug Chem· July 2006

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Structure-function engineering of interferon-beta-1b for improving stability, solubility, potency, immunogenicity, and pharmacokinetic properties by site-selective mono-PEGylation.
Amartya Basu, Karen Yang, Maoliang Wang, Sam Liu, Ramesh Chintala, David Filpula

Bioconjug Chem· July 2006

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Antitumor activity of poly(ethylene glycol)-camptothecin conjugate: the inhibition of tumor growth in vivo.
Deshan Yu, Ping Peng, Sonia S Dharap, Yang Wang, Mary Mehlig, David Filpula

J Control Release· December 2005

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Controlled release of proteins from their poly(ethylene glycol) conjugates: drug delivery systems employing 1,6-elimination.
Richard B Greenwald, Karen Yang, Hong Zhao, Charles D Conover, Stanford Lee, David Filpula

Bioconjug Chem· November 2003

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Tailoring structure-function and pharmacokinetic properties of single-chain Fv proteins by site-specific PEGylation.
Karen Yang, Amartya Basu, Maoliang Wang, Ramesh Chintala, Ming-Ching Hsieh, David Filpula

Protein Eng· October 2003

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