Publications by authors named "David Greaves"

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Cardiac lymphatics retain LYVE-1-dependent macrophages during neonatal mouse heart regeneration.
Benjamin G Chapman, Konstantinos Klaourakis, Carla de Villiers, Mala Gunadasa-Rohling, Maria-Alexa Cosma, David R Greaves

Nat Cardiovasc Res· October 2025

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Steric control of signaling bias in the immunometabolic receptor GPR84.
Pinqi Wang, Xuan Zhang, Abdul-Akim Guseinov, Laura Jenkins, Carl von Hallerstein, David R Greaves

bioRxiv· August 2025

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A papillary nodule of the hard palatal mucosa.
Richard J Vargo, Alivia M Shasteen, Emma K Barner, David E Greaves, Daniel C Stoeckel

J Am Dent Assoc· July 2025

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Effect of telehealth yoga on loneliness and social isolation among rural older adults: a randomized controlled trial.
Alan R Teo, Mary C Benton, Elizabeth R Hooker, Belle Zaccari, Nina J Hidalgo, David W Greaves

Aging Ment Health· May 2025

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Bacteriocin-like peptides encoded by a horizontally acquired island mediate Neisseria gonorrhoeae autolysis.
Katy Poncin, Samantha A McKeand, Hayley Lavender, Kacper Kurzyp, Odile B Harrison, David R Greaves

PLoS Biol· February 2025

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Biased agonists of GPR84 and insights into biological control.
Vincent B Luscombe, Pinqi Wang, Angela J Russell, David R Greaves

Br J Pharmacol· May 2024

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Ly6C Monocytes Are Metabolically Reprogrammed in the Blood during Inflammatory Stimulation and Require Intact OxPhos for Chemotaxis and Monocyte to Macrophage Differentiation.
Gareth S D Purvis, Eileen McNeill, Benjamin Wright, Keith M Channon, David R Greaves

Cells· May 2024

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Drug repurposing screen identifies novel anti-inflammatory activity of sunitinib in macrophages.
Laura E Chaffey, Annabell Roberti, Amelia Bowman, Conan Jo O'Brien, Liliana Som, David R Greaves

Eur J Pharmacol· April 2024

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Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment.
Jingyi Ma, Khatoun Al Moussawi, Hantao Lou, Hok Fung Chan, Yihua Wang, David R Greaves

Proc Natl Acad Sci U S A· March 2024

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Development of Highly Potent, G-Protein Pathway Biased, Selective, and Orally Bioavailable GPR84 Agonists.
Pinqi Wang, Arun Raja, Vincent B Luscombe, Carole J R Bataille, Daniel Lucy, David R Greaves

J Med Chem· January 2024

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OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity.
Gareth S D Purvis, Massimo Collino, Andrea D van Dam, Giacomo Einaudi, Yujung Ng, David R Greaves

Diabetes· January 2024

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Kinetic insights into agonist-dependent signalling bias at the pro-inflammatory G-protein coupled receptor GPR84.
Vincent B Luscombe, Luis Alberto Baena-López, Carole J R Bataille, Angela J Russell, David R Greaves

Eur J Pharmacol· October 2023

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CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout.
Savita Devi, Mohanalaxmi Indramohan, Elisabeth Jäger, Jessica Carriere, Lan H Chu, David R Greaves

Cell Rep· March 2023

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High Throughput Fluorescence-Based In Vitro Experimental Platform for the Identification of Effective Therapies to Overcome Tumour Microenvironment-Mediated Drug Resistance in AML.
Yoana Arroyo-Berdugo, Maria Sendino, David Greaves, Natalia Nojszewska, Orest Idilli

Cancers (Basel)· March 2023

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Drug repurposing in cardiovascular inflammation: Successes, failures, and future opportunities.
Laura Chaffey, Annabell Roberti, David R Greaves

Front Pharmacol· October 2022

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A Human CD68 Promoter-Driven Inducible Cre-Recombinase Mouse Line Allows Specific Targeting of Tissue Resident Macrophages.
Agata N Rumianek, Ben Davies, Keith M Channon, David R Greaves, Gareth S D Purvis

Front Immunol· July 2022

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Bruton's TK regulates myeloid cell recruitment during acute inflammation.
Gareth S D Purvis, Haidee Aranda-Tavio, Keith M Channon, David R Greaves

Br J Pharmacol· June 2022

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Epithelial Mesenchymal Transition (EMT) and Associated Invasive Adhesions in Solid and Haematological Tumours.
David Greaves, Yolanda Calle

Cells· February 2022

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NF-κB Signaling and Inflammation-Drug Repurposing to Treat Inflammatory Disorders?
Annabell Roberti, Laura Elizabeth Chaffey, David R Greaves

Biology (Basel)· February 2022

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X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure.
Caroline E O'Riordan, Gareth S D Purvis, Debora Collotta, Nadine Krieg, Bianka Wissuwa, David R Greaves

Front Immunol· June 2021

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Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart.
Thomas J Cahill, Xin Sun, Christophe Ravaud, Cristina Villa Del Campo, Konstantinos Klaourakis, David R Greaves

Development· February 2021

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How Have Leukocyte In Vitro Chemotaxis Assays Shaped Our Ideas about Macrophage Migration?
Agata N Rumianek, David R Greaves

Biology (Basel)· December 2020

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20 Years an Orphan: Is GPR84 a Plausible Medium-Chain Fatty Acid-Sensing Receptor?
Vincent B Luscombe, Daniel Lucy, Carole J R Bataille, Angela J Russell, David R Greaves

DNA Cell Biol· November 2020

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Inhibition of Bruton's TK regulates macrophage NF-κB and NLRP3 inflammasome activation in metabolic inflammation.
Gareth S D Purvis, Massimo Collino, Haidee Aranda-Tavio, Fausto Chiazza, Caroline E O'Riordan, David R Greaves

Br J Pharmacol· October 2020

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Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair.
Filipa C Simões, Thomas J Cahill, Amy Kenyon, Daria Gavriouchkina, Joaquim M Vieira, David R Greaves

Nat Commun· January 2020

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