Publications by authors named "David Groff"

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D3-GPC2-Directed CAR T Cells Are Safe and Efficacious in Preclinical Models of Neuroblastoma and Small Cell Lung Cancer.
Anna Maria Giudice, Stephanie Matlaga, Sydney L Roth, Whitney Gladney, David Groff

Clin Cancer Res· December 2025

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Defining the functional role and potential as an immunotherapeutic target of ALCAM in neuroblastoma.
Jarrett Lindsay, Jonathan Gaither, David Groff, Minu Samanta, Rebecca Kaufman

Mol Cancer Ther· November 2025

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Target antigen-displaying extracellular vesicles boost CAR T cell efficacy in cell and mouse models of neuroblastoma.
Anna Maria Giudice, Stephanie Matlaga, Sydney L Roth, Guillem Pascual-Pasto, Patrick M Schürch, David Groff

Sci Transl Med· November 2025

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A humanized anaplastic lymphoma kinase (ALK)-directed antibody-drug conjugate with pyrrolobenzodiazepine payload demonstrates efficacy in ALK-expressing cancers.
Alberto D Guerra, Smita Matkar, Christina Acholla, Colleen Casey, Grant Li, David Groff

Nat Commun· August 2025

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The PLK4 inhibitor RP-1664 demonstrates potent single-agent efficacy in neuroblastoma models through a dual mechanism of sensitivity.
John Maris, Isabel Soria-Bretones, Matias Casás-Selves, Minu Samanta, David Groff

Res Sq· July 2025

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Lineage dependence of the neuroblastoma surfaceome defines tumor cell state-dependent and -independent immunotherapeutic targets.
Nathan M Kendsersky, Michal Odrobina, Nathaniel W Mabe, Alvin Farrel, Liron Grossmann, David Groff

Neuro Oncol· June 2025

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Identification and Characterization of Chemotherapy-Resistant High-Risk Neuroblastoma Persister Cells.
Liron D Grossmann, Chia-Hui Chen, Yasin Uzun, Anusha Thadi, Adam J Wolpaw, David Groff

Cancer Discov· December 2024

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Lineage-dependence of the neuroblastoma surfaceome defines tumor cell state-dependent and independent immunotherapeutic targets.
Nathan M Kendsersky, Michal Odrobina, Nathaniel W Mabe, Alvin Farrel, Liron Grossmann, David Groff

bioRxiv· July 2024

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BARD1 germline variants induce haploinsufficiency and DNA repair defects in neuroblastoma.
Michael P Randall, Laura E Egolf, Zalman Vaksman, Minu Samanta, Matthew Tsang, David Groff

J Natl Cancer Inst· January 2024

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Targeting of intracellular oncoproteins with peptide-centric CARs.
Mark Yarmarkovich, Quinlen F Marshall, John M Warrington, Rasika Premaratne, Alvin Farrel, David Groff

Nature· November 2023

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Retraction Note: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Mark Yarmarkovich, Quinlen F Marshall, John M Warrington, Rasika Premaratne, Alvin Farrel, David Groff

Nature· November 2023

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germline variants induce haploinsufficiency and DNA repair defects in neuroblastoma.
Michael P Randall, Laura E Egolf, Zalman Vaksman, Minu Samanta, Matthew Tsang, David Groff

bioRxiv· February 2023

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Pre-clinical investigation of astatine-211-parthanatine for high-risk neuroblastoma.
Mehran Makvandi, Minu Samanta, Paul Martorano, Hwan Lee, Sarah B Gitto, David Groff

Commun Biol· November 2022

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Preclinical Development of [211At]meta- astatobenzylguanidine ([211At]MABG) as an Alpha Particle Radiopharmaceutical Therapy for Neuroblastoma.
Vandana Batra, Minu Samanta, Mehran Makvandi, David Groff, Paul Martorano

Clin Cancer Res· September 2022

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Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Mark Yarmarkovich, Quinlen F Marshall, John M Warrington, Rasika Premaratne, Alvin Farrel, David Groff

Nature· November 2021

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The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models.
Nathan M Kendsersky, Jarrett Lindsay, E Anders Kolb, Malcolm A Smith, Beverly A Teicher, David Groff

Clin Cancer Res· May 2021

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Neonatal GLP1R activation limits adult adiposity by durably altering hypothalamic architecture.
Andrea V Rozo, Daniella A Babu, PoMan A Suen, David N Groff, Randy J Seeley

Mol Metab· July 2017

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ATF5 regulates β-cell survival during stress.
Christine A Juliana, Juxiang Yang, Andrea V Rozo, Austin Good, David N Groff

Proc Natl Acad Sci U S A· February 2017

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LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.
Benjamin N Ediger, Hee-Woong Lim, Christine Juliana, David N Groff, LaQueena T Williams

J Clin Invest· January 2017

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Diabetes Susceptibility Genes Pdx1 and Clec16a Function in a Pathway Regulating Mitophagy in β-Cells.
Scott A Soleimanpour, Alana M Ferrari, Jeffrey C Raum, David N Groff, Juxiang Yang

Diabetes· October 2015

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Tshz1 Regulates Pancreatic β-Cell Maturation.
Jeffrey C Raum, Scott A Soleimanpour, David N Groff, Nathalie Coré, Laurent Fasano

Diabetes· August 2015

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The Polycomb protein, Bmi1, regulates insulin sensitivity.
Corey E Cannon, Paul M Titchenell, David N Groff, Abdelfattah El Ouaamari, Rohit N Kulkarni

Mol Metab· November 2014

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The diabetes susceptibility gene Clec16a regulates mitophagy.
Scott A Soleimanpour, Aditi Gupta, Marina Bakay, Alana M Ferrari, David N Groff

Cell· June 2014

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Calcineurin signaling regulates human islet {beta}-cell survival.
Scott A Soleimanpour, Michael F Crutchlow, Alana M Ferrari, Jeffrey C Raum, David N Groff

J Biol Chem· December 2010

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Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice.
Kathryn C Claiborn, Mira M Sachdeva, Corey E Cannon, David N Groff, Jeffrey D Singer

J Clin Invest· October 2010

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