Publications by authors named "David Hymel"

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Photochemically-enabled, post-translational production of C-terminal amides.
David Hymel, Felix Wojcik, Kim S Halskov, Wouter F J Hogendorf, Sydnee C Wong

Nat Commun· November 2024

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Development of ultra-high affinity bivalent ligands targeting the polo-like kinase 1.
Kohei Tsuji, David Hymel, Buyong Ma, Hirokazu Tamamura, Ruth Nussinov

RSC Chem Biol· August 2022

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Unanticipated Characteristics of a Selective, Potent Neuromedin-U Receptor 2 Agonist.
Suneet Mehrotra, Sebastian Lam, Elizabeth Glenn, David Hymel, Christina A Sanford

ACS Bio Med Chem Au· August 2022

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Design and synthesis of a new orthogonally protected glutamic acid analog and its use in the preparation of high affinity polo-like kinase 1 polo-box domain - binding peptide macrocycles.
David Hymel, Kohei Tsuji, Robert A Grant, Ramesh M Chingle, Dominique L Kunciw

Org Biomol Chem· September 2021

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Conventional and Chemically Programmed Asymmetric Bispecific Antibodies Targeting Folate Receptor 1.
Junpeng Qi, David Hymel, Christopher G Nelson, Terrence R Burke, Christoph Rader

Front Immunol· October 2020

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A new genre of fluorescence recovery assay to evaluate polo-like kinase 1 ATP-competitive inhibitors.
Kohei Tsuji, David Hymel, Terrence R Burke

Anal Methods· September 2020

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Further Exploration of Hydrazine-Mediated Bioconjugation Chemistries.
Melrose Mailig, David Hymel, Fa Liu

Org Lett· August 2020

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Chemically Programmable and Switchable CAR-T Therapy.
Junpeng Qi, Kohei Tsuji, David Hymel, Terrence R Burke, Michael Hudecek

Angew Chem Int Ed Engl· July 2020

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Colorado community pharmacists' survey and their perspectives regarding marijuana.
Leticia A Shea, Micheline A Goldwire, David Hymel, Doan Bui

SAGE Open Med· July 2020

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Selective Lysine Modification Enabled by Intramolecular Acyl Transfer.
David Hymel, Fa Liu

Org Lett· April 2020

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Antibody-Drug Conjugate that Exhibits Synergistic Cytotoxicity with an Endosome-Disruptive Peptide.
Kelsey E Knewtson, Chamani Perera, David Hymel, Zhe Gao, Molly M Lee

ACS Omega· July 2019

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Development of Highly Selective 1,2,3-Triazole-containing Peptidic Polo-like Kinase 1 Polo-box Domain-binding Inhibitors.
Xue Zhi Zhao, Kohei Tsuji, David Hymel, Terrence R Burke

Molecules· April 2019

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Histidine N(τ)-cyclized macrocycles as a new genre of polo-like kinase 1 polo-box domain-binding inhibitors.
David Hymel, Robert A Grant, Kohei Tsuji, Michael B Yaffe, Terrence R Burke

Bioorg Med Chem Lett· October 2018

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Enhancing polo-like kinase 1 selectivity of polo-box domain-binding peptides.
Xue Zhi Zhao, David Hymel, Terrence R Burke

Bioorg Med Chem· October 2017

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Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates.
Alex R Nanna, Xiuling Li, Even Walseng, Lee Pedzisa, Rebecca S Goydel, David Hymel

Nat Commun· October 2017

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Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets.
Xiuxiu Lu, Urszula Nowicka, Vinidhra Sridharan, Fen Liu, Leah Randles, David Hymel

Nat Commun· June 2017

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Current progress and future perspectives in the development of anti-polo-like kinase 1 therapeutic agents.
Jung-Eun Park, David Hymel, Terrence R Burke, Kyung S Lee

F1000Res· June 2017

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Stable and Potent Selenomab-Drug Conjugates.
Xiuling Li, Christopher G Nelson, Rajesh R Nair, Lori Hazlehurst, Tina Moroni, David Hymel

Cell Chem Biol· April 2017

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Phosphatase-Stable Phosphoamino Acid Mimetics That Enhance Binding Affinities with the Polo-Box Domain of Polo-like Kinase 1.
David Hymel, Terrence R Burke

ChemMedChem· February 2017

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Corrigendum: Phosphatase-Stable Phosphoamino Acid Mimetics That Enhance Binding Affinities with the Polo-Box Domain of Polo-like Kinase 1.
David Hymel, Terrence R Burke

ChemMedChem· February 2017

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Application of oxime-diversification to optimize ligand interactions within a cryptic pocket of the polo-like kinase 1 polo-box domain.
Xue Zhi Zhao, David Hymel, Terrence R Burke

Bioorg Med Chem Lett· October 2016

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Fluorescent mimics of cholesterol that rapidly bind surfaces of living mammalian cells.
David Hymel, Sutang Cai, Qi Sun, Rebecca S Henkhaus, Chamani Perera

Chem Commun (Camb)· October 2015

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Detection of protein-protein interactions by proximity-driven S(N)Ar reactions of lysine-linked fluorophores.
David Hymel, Zachary R Woydziak, Blake R Peterson

J Am Chem Soc· April 2014

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Synthetic cell surface receptors for delivery of therapeutics and probes.
David Hymel, Blake R Peterson

Adv Drug Deliv Rev· June 2012

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Adipose tissue collagen VI in obesity.
Magdalena Pasarica, Barbara Gowronska-Kozak, David Burk, Isabel Remedios, David Hymel

J Clin Endocrinol Metab· December 2009

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