Publications by authors named "David J Blake"

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Fragment-Based Drug Discovery of Novel High-affinity, Selective, and Anti-inflammatory Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction.
Chunyu Lin, Dilip Narayanan, Marilia Barreca, Cecilie Poulsen, Leandro Silva da Costa, David J Blake

Angew Chem Int Ed Engl· September 2025

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Improved synthesis of deoxyalpinoid B and quantification of antileishmanial activity of deoxyalpinoid B and sulforaphane.
Emma Leary, Ethan T Anderson, Jasmine K Keyes, Tristan R Huskie, David J Blake

Bioorg Med Chem· January 2023

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Caffeic Acid Esters Are Effective Bactericidal Compounds Against by Altering Intracellular Oxidant and Antioxidant Levels.
William Collins, Noah Lowen, David J Blake

Biomolecules· July 2019

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Ablation of the CD9 receptor in human lung cancer cells using CRISPR/Cas alters migration to chemoattractants including IL-16.
David J Blake, Jonathon D Martiszus, Tia H Lone, Steven D Fenster

Cytokine· November 2018

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Synthesis and Characterization of -Dichlorotetrakis(imidazole)cobalt(III) Chloride: A New Cobalt(III) Coordination Complex with Potential Prodrug Properties.
Kaila F Hart, Natalie S Joe, Rebecca M Miller, Hannah P Nash, David J Blake

Bioinorg Chem Appl· September 2018

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Soluble extracellular Klotho decreases sensitivity to cigarette smoke induced cell death in human lung epithelial cells.
David J Blake, Caitlyn M Reese, Mario Garcia, Elizabeth A Dahlmann, Alexander Dean

Toxicol In Vitro· October 2015

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Antiviral activity of (+)-sattabacin against varicella zoster.
Serena R Mancha, Christopher M Regnery, Joshua R Dahlke, Kenneth A Miller, David J Blake

Bioorg Med Chem Lett· January 2013

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Sulforaphane inhibits de novo synthesis of IL-8 and MCP-1 in human epithelial cells generated by cigarette smoke extract.
Warren Starrett, David J Blake

J Immunotoxicol· June 2011

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4-Methyl-3-nitro-benzoic acid, a migration inhibitor, prevents breast cancer metastasis in SCID mice.
Hua Guo, Menghui Li, Peng Chen, David J Blake, Xiaoni Kong

Cancer Lett· June 2011

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Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation.
David J Blake, Anju Singh, Ponvijay Kombairaju, Deepti Malhotra, Thomas J Mariani

Am J Respir Cell Mol Biol· May 2010

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Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice.
Thomas E Sussan, Tirumalai Rangasamy, David J Blake, Deepti Malhotra, Hazim El-Haddad

Proc Natl Acad Sci U S A· January 2009

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Separation and characterization of respirable amphibole fibers from Libby, Montana.
James S Webber, David J Blake, Tony J Ward, Jean C Pfau

Inhal Toxicol· June 2008

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Autoantibodies from mice exposed to Libby amphibole asbestos bind SSA/Ro52-enriched apoptotic blebs of murine macrophages.
David J Blake, Scott A Wetzel, Jean C Pfau

Toxicology· April 2008

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Asbestos-induced autoimmunity in C57BL/6 mice.
Jean C Pfau, Jami J Sentissi, Sheng'ai Li, Lilian Calderon-Garciduenas, Jared M Brown, David J Blake

J Immunotoxicol· April 2008

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Internalization of Libby amphibole asbestos and induction of oxidative stress in murine macrophages.
David J Blake, Celeste M Bolin, David P Cox, Fernando Cardozo-Pelaez, Jean C Pfau

Toxicol Sci· September 2007

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Quantification of Feline immunodeficiency virus (FIVpco) in peripheral blood mononuclear cells, lymph nodes and plasma of naturally infected cougars.
David J Blake, Jon Graham, Mary Poss

J Gen Virol· April 2006

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Fibroblast growth factor receptor-1 mediates the inhibition of endothelial cell proliferation and the promotion of skeletal myoblast differentiation by SPARC: a role for protein kinase A.
Kouros Motamed, David J Blake, John C Angello, Benjamin L Allen, Alan C Rapraeger

J Cell Biochem· October 2003

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SPARC regulates cell cycle progression in mesangial cells via its inhibition of IGF-dependent signaling.
Aleksandar Francki, Kouros Motamed, Timothy D McClure, Marcus Kaya, Carrie Murri, David J Blake

J Cell Biochem· March 2003

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