Publications by authors named "David J Dooling"

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Genome Modeling System: A Knowledge Management Platform for Genomics.
Malachi Griffith, Obi L Griffith, Scott M Smith, Avinash Ramu, Matthew B Callaway, David J Dooling

PLoS Comput Biol· July 2015

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RB1 gene inactivation by chromothripsis in human retinoblastoma.
Justina McEvoy, Panduka Nagahawatte, David Finkelstein, Jennifer Richards-Yutz, Marcus Valentine, David J Dooling

Oncotarget· January 2014

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DGIdb: mining the druggable genome.
Malachi Griffith, Obi L Griffith, Adam C Coffman, James V Weible, Josh F McMichael, David J Dooling

Nat Methods· December 2013

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Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas.
Jinghui Zhang, Gang Wu, Claudia P Miller, Ruth G Tatevossian, James D Dalton, David J Dooling

Nat Genet· June 2013

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The genomic landscape of hypodiploid acute lymphoblastic leukemia.
Linda Holmfeldt, Lei Wei, Ernesto Diaz-Flores, Michael Walsh, Jinghui Zhang, David J Dooling

Nat Genet· March 2013

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Genomic landscape of non-small cell lung cancer in smokers and never-smokers.
Ramaswamy Govindan, Li Ding, Malachi Griffith, Janakiraman Subramanian, Nathan D Dees, David J Dooling

Cell· September 2012

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Novel mutations target distinct subgroups of medulloblastoma.
Giles Robinson, Matthew Parker, Tanya A Kranenburg, Charles Lu, Xiang Chen, David J Dooling

Nature· August 2012

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The origin and evolution of mutations in acute myeloid leukemia.
John S Welch, Timothy J Ley, Daniel C Link, Christopher A Miller, David E Larson, David J Dooling

Cell· July 2012

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Whole-genome analysis informs breast cancer response to aromatase inhibition.
Matthew J Ellis, Li Ding, Dong Shen, Jingqin Luo, Vera J Suman, David J Dooling

Nature· June 2012

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SomaticSniper: identification of somatic point mutations in whole genome sequencing data.
David E Larson, Christopher C Harris, Ken Chen, Daniel C Koboldt, Travis E Abbott, David J Dooling

Bioinformatics· February 2012

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A vertebrate case study of the quality of assemblies derived from next-generation sequences.
Liang Ye, LaDeana W Hillier, Patrick Minx, Nay Thane, Devin P Locke, David J Dooling

Genome Biol· January 2012

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A novel retinoblastoma therapy from genomic and epigenetic analyses.
Jinghui Zhang, Claudia A Benavente, Justina McEvoy, Jacqueline Flores-Otero, Li Ding, David J Dooling

Nature· January 2012

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Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing.
Li Ding, Timothy J Ley, David E Larson, Christopher A Miller, Daniel C Koboldt, David J Dooling

Nature· January 2012

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The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.
Jinghui Zhang, Li Ding, Linda Holmfeldt, Gang Wu, Sue L Heatley, David J Dooling

Nature· January 2012

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Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes.
Timothy A Graubert, Dong Shen, Li Ding, Theresa Okeyo-Owuor, Cara L Lunn, David J Dooling

Nat Genet· December 2011

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Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML.
Daniel C Link, Laura G Schuettpelz, Dong Shen, Jinling Wang, Matthew J Walter, David J Dooling

JAMA· April 2011

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DNMT3A mutations in acute myeloid leukemia.
Timothy J Ley, Li Ding, Matthew J Walter, Michael D McLellan, Tamara Lamprecht, David J Dooling

N Engl J Med· December 2010

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Genome remodelling in a basal-like breast cancer metastasis and xenograft.
Li Ding, Matthew J Ellis, Shunqiang Li, David E Larson, Ken Chen, David J Dooling

Nature· April 2010

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Recurring mutations found by sequencing an acute myeloid leukemia genome.
Elaine R Mardis, Li Ding, David J Dooling, David E Larson, Michael D McLellan

N Engl J Med· September 2009

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Somatic mutations affect key pathways in lung adenocarcinoma.
Li Ding, Gad Getz, David A Wheeler, Elaine R Mardis, Michael D McLellan, David J Dooling

Nature· October 2008

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Design and implementation of a generalized laboratory data model.
Michael C Wendl, Scott Smith, Craig S Pohl, David J Dooling, Asif T Chinwalla

BMC Bioinformatics· September 2007

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Open-source answer to bibliography problem.
Michael C Wendl, David J Dooling

Nature· August 2003

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