Publications by authors named "David L Spector"

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Longitudinal tracking of level over a breast cancer patient's course of treatment and disease progression.
Disha Aggarwal, Tse-Luen Wee, Shuchismita Satpathy, Suzanne Russo, David L Spector

Mol Ther Oncol· December 2025

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LINC01235 Is an Upstream Regulator of the NFIB Gene and the Notch Pathway in Triple-Negative Breast Cancer.
Wenbo Xu, Sonam Bhatia, Yunus Sahin, David L Spector

Mol Cancer Res· October 2025

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Loss of BPTF restores estrogen response and suppresses metastasis of mammary tumors.
Michael F Ciccone, Dhivyaa Anandan, Deeptiman Chatterjee, Chen Chen, Marygrace C Trousdell, David L Spector

Nat Commun· October 2025

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On-target toxicity limits the efficacy of CDK11 inhibition against cancers with 1p36 deletions.
Linda Julian, Lisa Crozier, Devon Lukow, Sanat Mishra, Aditi Swamy, David L Spector

bioRxiv· August 2025

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A sub-set of guanine- and cytosine-rich genes are actively transcribed at the nuclear Lamin B1 region.
Gayan I Balasooriya, Tse-Luen Wee, David L Spector

bioRxiv· March 2025

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MARK2/MARK3 Kinases Are Catalytic Codependencies of YAP/TAZ in Human Cancer.
Olaf Klingbeil, Damianos Skopelitis, Claudia Tonelli, Toyoki Yoshimoto, Aktan Alpsoy, David L Spector

Cancer Discov· December 2024

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Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome.
Michael P East, Robert W Sprung, Denis O Okumu, J Felix Olivares-Quintero, Chinmaya U Joisa, David L Spector

bioRxiv· October 2024

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The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade.
Yijian Qiu, Olivia T Stamatatos, Qingting Hu, Jed Ruiter Swain, Suzanne Russo, David L Spector

Nat Metab· August 2024

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Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma.
Diogo Maia-Silva, Patrick J Cunniff, Allison C Schier, Damianos Skopelitis, Marygrace C Trousdell, David L Spector

Nat Genet· July 2024

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Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment.
Xue-Yan He, Yuan Gao, David Ng, Evdokia Michalopoulou, Shanu George, David L Spector

Cancer Cell· March 2024

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Identification of glioblastoma stem cell-associated lncRNAs using single-cell RNA sequencing datasets.
Rasmani Hazra, Raditya Utama, Payal Naik, Alexander Dobin, David L Spector

Stem Cell Reports· November 2023

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Long non-coding RNAs: definitions, functions, challenges and recommendations.
John S Mattick, Paulo P Amaral, Piero Carninci, Susan Carpenter, Howard Y Chang, David L Spector

Nat Rev Mol Cell Biol· June 2023

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Testing for Phylogenetic Signal in Single-Cell RNA-Seq Data.
Jiří C Moravec, Robert Lanfear, David L Spector, Sarah D Diermeier, Alex Gavryushkin

J Comput Biol· April 2023

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Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation.
Alexandra Mousset, Enora Lecorgne, Isabelle Bourget, Pascal Lopez, Kitti Jenovai, David L Spector

Cancer Cell· April 2023

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Allele pairing at Sun1-enriched domains at the nuclear periphery via tandem DNA repeats.
Gayan I Balasooriya, David L Spector

bioRxiv· April 2023

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Establishment and Culture of Patient-Derived Breast Organoids.
Disha Aggarwal, Suzanne Russo, Payal Naik, Sonam Bhatia, David L Spector

J Vis Exp· February 2023

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Identification of glioblastoma stem cell-associated lncRNAs using single-cell RNA-sequencing datasets.
Rasmani Hazra, Raditya Utama, Payal Naik, Alexander Dobin, David L Spector

bioRxiv· January 2023

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Single Oligonucleotide Capture of RNA And Temperature Elution Series ( ) for Identification of RNA-binding Proteins.
Allen T Yu, Disha Aggarwal, Darryl Pappin, David L Spector

Bio Protoc· December 2022

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Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment.
Rasmani Hazra, Lily Brine, Libia Garcia, Brian Benz, Napon Chirathivat, David L Spector

Dev Cell· November 2022

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Allele-specific differential regulation of monoallelically expressed autosomal genes in the cardiac lineage.
Gayan I Balasooriya, David L Spector

Nat Commun· October 2022

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Simultaneous visualization of RNA transcripts and proteins in whole-mount mouse preimplantation embryos using single-molecule fluorescence hybridization and immunofluorescence microscopy.
Rasmani Hazra, David L Spector

Front Cell Dev Biol· October 2022

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Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics.
Sonam Bhatia, Melissa Kramer, Suzanne Russo, Payal Naik, Gayatri Arun, David L Spector

Cancer Res· April 2022

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Noncoding RNAs: biology and applications-a Keystone Symposia report.
Jennifer Cable, Edith Heard, Tetsuro Hirose, Kannanganattu V Prasanth, Ling-Ling Chen, David L Spector

Ann N Y Acad Sci· December 2021

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Activating a collaborative innate-adaptive immune response to control metastasis.
Lijuan Sun, Tim Kees, Ana Santos Almeida, Bodu Liu, Xue-Yan He, David L Spector

Cancer Cell· October 2021

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lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR.
Allen T Yu, Carmen Berasain, Sonam Bhatia, Keith Rivera, Bodu Liu, David L Spector

Elife· May 2021

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