Publications by authors named "David Leib"

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Autophagy machinery as exploited by viruses.
Christian Münz, Grant R Campbell, Audrey Esclatine, Mathias Faure, Patrick Labonte, David Leib

Autophagy Rep· December 2025

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Eliminating interactions with the viral Fc receptor improves antibody-mediated protection against neonatal HSV infection in mice.
Matthew D Slein, Iara M Backes, Lesle M Jiménez, Natasha S Kelkar, Callaghan R Garland, David A Leib

Sci Transl Med· November 2025

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Herpes simplex virus 1 ICP34.5 acts to maintain latency in human and mouse neurons.
Paige N Canova, Sarah Katzenell, Stacey Cerón, Audra J Charron, Jean M Pesola, David A Leib

Virology· October 2025

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Corrigendum to "Herpes simplex virus 1 ICP34.5 acts to maintain latency in human and mouse neurons" [Virology 611 (2025) 110652].
Paige N Canova, Sarah Katzenell, Stacey Ceron, Audra J Charron, Jean M Pesola, David A Leib

Virology· October 2025

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Maternal Antibodies to Neurovirulent Pathogens in Fetal Tissues.
Matthew D Slein, Margaret E Ackerman, David A Leib

Annu Rev Virol· September 2025

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Herpes Simplex Virus Neurovirulence Across the Human Lifespan.
Abigail J Dutton, Cooper K Hayes, David A Leib, Lisa N Akhtar

J Infect Dis· July 2025

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Antibodies targeting HSV glycoprotein B require effector functions to protect neonatal mice.
Matthew D Slein, Lesle M Jiménez, Iara M Backes, Evelyn M Turnbaugh, Callaghan R Garland, David A Leib

bioRxiv· July 2025

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An AAV variant selected through NHP screens robustly transduces the brain and drives secreted protein expression in NHPs and mice.
Luis Tecedor, Yong Hong Chen, David E Leib, Paul T Ranum, Megan S Keiser

Sci Transl Med· May 2025

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Regulation of the innate immune response in human neurons by ICP34.5 maintains herpes simplex virus 1 latency.
Paige N Canova, Sarah Katzenell, Stacey Cerón, Audra J Charron, Jean M Pesola, David A Leib

bioRxiv· April 2025

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Asymptomatic neonatal herpes simplex virus infection in mice leads to persistent CNS infection and long-term cognitive impairment.
Abigail J Dutton, Evelyn M Turnbaugh, Chaya D Patel, Callaghan R Garland, Sean A Taylor, David A Leib

PLoS Pathog· February 2025

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Improving antibody-mediated protection against HSV infection by eliminating interactions with the viral Fc receptor gE/gI.
Matthew D Slein, Iara M Backes, Natasha S Kelkar, Callaghan R Garland, Urjeet S Khanwalkar, David A Leib

bioRxiv· November 2024

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Models of Herpes Simplex Virus Latency.
Paige N Canova, Audra J Charron, David A Leib

Viruses· May 2024

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Effector functions are required for broad and potent protection of neonatal mice with antibodies targeting HSV glycoprotein D.
Matthew D Slein, Iara M Backes, Callaghan R Garland, Natasha S Kelkar, David A Leib

Cell Rep Med· February 2024

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Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A Fischer, Kyota Fujita, David E Leib

Cell· October 2023

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Antibody effector functions are required for broad and potent protection of neonates from herpes simplex virus infection.
Matthew D Slein, Iara M Backes, Callaghan R Garland, Natasha S Kelkar, David A Leib

bioRxiv· August 2023

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Virology under the Microscope-a Call for Rational Discourse.
Felicia Goodrum, Anice C Lowen, Seema Lakdawala, James Alwine, Arturo Casadevall, David Leib

mSphere· April 2023

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Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates.
Yvonne J Rosenberg, Tracy Ordonez, Urjeet S Khanwalkar, Philip Barnette, Shilpi Pandey, David A Leib

mBio· April 2023

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Cochlear transduction via cerebrospinal fluid delivery of AAV in non-human primates.
Paul T Ranum, Luis Tecedor, Megan S Keiser, Yong Hong Chen, David E Leib

Mol Ther· March 2023

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Virology under the Microscope-a Call for Rational Discourse.
Felicia Goodrum, Anice C Lowen, Seema Lakdawala, James Alwine, Arturo Casadevall, David Leib

J Virol· February 2023

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Virology under the Microscope-a Call for Rational Discourse.
Felicia Goodrum, Anice C Lowen, Seema Lakdawala, James Alwine, Arturo Casadevall, David Leib

mBio· February 2023

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Maternally transferred mAbs protect neonatal mice from HSV-induced mortality and morbidity.
Iara M Backes, Brook K Byrd, Matthew D Slein, Chaya D Patel, Sean A Taylor, David A Leib

J Exp Med· December 2022

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Herpes Simplex Virus-2 Variation Contributes to Neurovirulence During Neonatal Infection.
Cooper K Hayes, Christopher K Villota, Fiona B McEnany, Stacey Cerón, Sita Awasthi, David A Leib

J Infect Dis· November 2022

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Monoclonal antibody therapy of herpes simplex virus: An opportunity to decrease congenital and perinatal infections.
Iara M Backes, David A Leib, Margaret E Ackerman

Front Immunol· August 2022

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Limited astrocyte-to-neuron conversion in the mouse brain using NeuroD1 overexpression.
David Leib, Yong Hong Chen, Alex Mas Monteys, Beverly L Davidson

Mol Ther· March 2022

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Soma-Targeted Imaging of Neural Circuits by Ribosome Tethering.
Yiming Chen, Heeun Jang, Perry W E Spratt, Seher Kosar, David E Taylor, David E Leib

Neuron· August 2020

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