Publications by authors named "David Linch"

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Early rituximab monotherapy versus watchful waiting for advanced stage, asymptomatic, low tumour burden follicular lymphoma: long-term results of a randomised, phase 3 trial.
Michael Northend, William Wilson, Kushani Ediriwickrema, Laura Clifton-Hadley, Wendi Qian, David C Linch

Lancet Haematol· May 2025

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Quality of life in advanced-stage, asymptomatic, non-bulky follicular lymphoma treated with rituximab shows significant improvement compared with watchful-waiting.
Maria A V Marzolini, Wendi Qian, Laura Clifton-Hadley, Pip Patrick, June Warden, David C Linch

Br J Haematol· March 2025

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In Situ Tracking of TCRβ Isoforms for Detection of T Cell Clonality: Implication for Precision Diagnosis and Targeted Immunotherapy of T-Cell Neoplasms.
Marie Therese Manipadam, Andrea Marra, Alan Ramsay, Sugerdana Padmasri, Adheesh Gosh, David Linch

Hematol Oncol· January 2025

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Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients.
Adriane Halik, Marlon Tilgner, Patricia Silva, Natalia Estrada, Robert Altwasser, David C Linch

J Hematol Oncol· August 2024

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Prognostic impact of CEBPA mutational subgroups in adult AML.
Julia-Annabell Georgi, Sebastian Stasik, Michael Kramer, Manja Meggendorfer, Christoph Röllig, David Linch

Leukemia· February 2024

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Microenvironmental immune cell alterations across the spectrum of nodular lymphocyte predominant Hodgkin lymphoma and T-cell/histiocyte-rich large B-cell lymphoma.
Christos Panayi, Ayse U Akarca, Alan D Ramsay, Ananth G Shankar, Brunangelo Falini, David Linch

Front Oncol· October 2023

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Dual targeting of CD19 and CD22 with bicistronic CAR-T cells in patients with relapsed/refractory large B-cell lymphoma.
Claire Roddie, Lazaros J Lekakis, Maria A V Marzolini, Aravind Ramakrishnan, Yiyun Zhang, David C Linch

Blood· May 2023

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High inter-follicular spatial co-localization of CD8+FOXP3+ with CD4+CD8+ cells predicts favorable outcome in follicular lymphoma.
Yeman B Hagos, Ayse U Akarca, Alan Ramsay, Riccardo L Rossi, Sabine Pomplun, David Linch

Hematol Oncol· October 2022

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Therapy for isocitrate dehydrogenase 2 (IDH2) -mutant acute myeloid leukaemia.
David C Linch, Robert K Hills, Alan K Burnett, Nigel Russell, Rosemary E Gale

Br J Haematol· March 2022

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Samuel J Machin MB ChB FRCP FRCPath.
David Linch

Lupus· March 2022

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Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia.
Wei-Yu Lin, Sarah E Fordham, Eric Hungate, Nicola J Sunter, Claire Elstob, David Linch

Nat Commun· January 2022

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Durable Responses and Low Toxicity After Fast Off-Rate CD19 Chimeric Antigen Receptor-T Therapy in Adults With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia.
Claire Roddie, Juliana Dias, Maeve A O'Reilly, Mahnaz Abbasian, Amaia Cadinanos-Garai, David C Linch

J Clin Oncol· October 2021

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Genome-wide association study identifies susceptibility loci for acute myeloid leukemia.
Wei-Yu Lin, Sarah E Fordham, Eric Hungate, Nicola J Sunter, Claire Elstob, David Linch

Nat Commun· October 2021

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Additional impact of mutational genotype on prognostic determination in resistant and relapsed acute myeloid leukaemia.
David C Linch, Robert K Hills, Amanda Gilkes, Alan K Burnett, Nigel Russell

Leuk Res· September 2021

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Prognostic indices in diffuse large B-cell lymphoma in the rituximab era: an analysis of the UK National Cancer Research Institute R-CHOP 14 versus 21 phase 3 trial.
Mary Gleeson, Nicholas Counsell, David Cunningham, Anthony Lawrie, Laura Clifton-Hadley, David Linch

Br J Haematol· March 2021

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Developments over the last 60 years in diffuse large B-cell lymphomas.
David Linch

Br J Haematol· November 2020

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Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study.
Alvina G Lai, Laura Pasea, Amitava Banerjee, Geoff Hall, Spiros Denaxas, David Linch

BMJ Open· November 2020

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Favourable outcomes for high-risk Burkitt lymphoma patients (IPI 3-5) treated with rituximab plus CODOX-M/IVAC: Results of a phase 2 UK NCRI trial.
Elizabeth H Phillips, Catherine Burton, Amy A Kirkwood, Sharon Barrans, Anthony Lawrie, David C Linch

EJHaem· July 2020

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-Deficient T-cell Acute Lymphoblastic Leukemia Is Sensitized to CHK1 Inhibition through Enhanced Replication Stress.
Theresa E León, Tanya Rapoz-D'Silva, Cosetta Bertoli, Sunniyat Rahman, Michael Magnussen, David C Linch

Cancer Discov· July 2020

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The clinical impact of mutant DNMT3A R882 variant allele frequency in acute myeloid leukaemia.
David C Linch, Robert K Hills, Alan K Burnett, Rosemary E Gale

Br J Haematol· May 2020

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Treatment of classical Hodgkin lymphoma in young adults aged 18-30 years with a modified paediatric Hodgkin lymphoma protocol. Results of a multicentre phase II clinical trial (CRUK/08/012).
William Townsend, Sarah Leong, Peter Hoskin, Patricia Diez, Pip Patrick, David Linch

Br J Haematol· April 2020

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Analysis of the clinical impact of NPM1 mutant allele burden in a large cohort of younger adult patients with acute myeloid leukaemia.
David C Linch, Robert K Hills, Alan K Burnett, Nigel Russell, Rosemary E Gale

Br J Haematol· March 2020

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In trans early mosaic mutational escape and novel phenotypic features of germline SAMD9 mutation.
Catherine Hockings, Satyen Gohil, Robin Dowse, Yvette Hoade, Marc R Mansour, David C Linch

Br J Haematol· February 2020

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Novel markers in pediatric-type follicular lymphoma.
Claudio Agostinelli, Ayse U Akarca, Alan Ramsay, Hasan Rizvi, Manuel Rodriguez-Justo, David Linch

Virchows Arch· December 2019

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Allo-HSCT in transplant-naïve patients with Hodgkin lymphoma: a single-arm, multicenter study.
Emma Das-Gupta, Kirsty J Thomson, Adrian J C Bloor, Andrew D Clark, Stephen Mackinnon, David C Linch

Blood Adv· December 2019

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