Publications by authors named "David Lok"

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NMR and SPR Fragment-Based Screening Can Produce Novel High Affinity Small Molecule Hits against Structured RNAs.
Brooke X C Kwai, Indu R Chandrashekaran, Biswaranjan Mohanty, Menachem J Gunzburg, Bradley C Doak, David Lok

ACS Chem Biol· December 2025

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Identification of a Novel Linker Enabling the Bioconjugation of a Cyclic Dinucleotide for the STING Antibody-Drug Conjugate TAK-500.
Hong Myung Lee, Kojo Abdul-Hadi, Vicky A Appleman, David Cardin, Linlin Dong, David Lok

Bioconjug Chem· November 2025

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Investigation of the enhanced antitumour potency of STING agonist after conjugation to polymer nanoparticles.
Pere Dosta, Alexander M Cryer, Michelle Z Dion, Tsubasa Shiraishi, Steven P Langston, David Lok

Nat Nanotechnol· November 2023

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Identification of Novel Carbocyclic Pyrimidine Cyclic Dinucleotide STING Agonists for Antitumor Immunotherapy Using Systemic Intravenous Route.
Stepan Vyskocil, David Cardin, Jeffrey Ciavarri, Joe Conlon, Courtney Cullis, David Lok

J Med Chem· May 2021

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Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer.
Steven P Langston, Stephen Grossman, Dylan England, Roushan Afroze, Neil Bence, David Lok

J Med Chem· March 2021

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Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors.
Shih-Chung Huang, Sharmila Adhikari, James E Brownell, Emily F Calderwood, Jouhara Chouitar, David Lok

Bioorg Med Chem· October 2020

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Development of a novel noncapillary plasma microsampling device for ultra-low volume of blood collection.
Ji Zhang, David Lok, Jesse Gray, Steve Grossman, Matt Jones

Bioanalysis· May 2016

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Bonding as a positive youth development construct: a conceptual review.
Tak Yan Lee, David P P Lok

ScientificWorldJournal· October 2012

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Emotion regulation mediates age differences in emotions.
Dannii Y Yeung, Carmen K M Wong, David P P Lok

Aging Ment Health· April 2011

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