Publications by authors named "David M Rotstein"

Claim this Profile
A
A study of the molecular mechanism of binding kinetics and long residence times of human CCR5 receptor small molecule allosteric ligands.
David C Swinney, Paul Beavis, Kai-Ting Chuang, Yue Zheng, Ina Lee, David M Rotstein

Br J Pharmacol· July 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of amide replacements in CCR5 antagonists as a means to increase intrinsic permeability. Part 2: SAR optimization and pharmacokinetic profile of a homologous azacyle series.
Jutta Wanner, Lijing Chen, Rémy C Lemoine, Rama Kondru, Andreas Jekle, David M Rotstein

Bioorg Med Chem Lett· November 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Exploration of a new series of CCR5 antagonists: multi-dimensional optimization of a sub-series containing N-substituted pyrazoles.
Rémy C Lemoine, Ann C Petersen, Lina Setti, Andreas Jekle, Gabrielle Heilek, David M Rotstein

Bioorg Med Chem Lett· August 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis, SAR and evaluation of [1,4']-bipiperidinyl-4-yl-imidazolidin-2-one derivatives as novel CCR5 antagonists.
David M Rotstein, Stephen D Gabriel, Nicole Manser, Lubov Filonova, Fernando Padilla

Bioorg Med Chem Lett· June 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel hexahydropyrrolo[3,4-c]pyrrole CCR5 antagonists.
David M Rotstein, Chris R Melville, Fernando Padilla, Dick Cournoyer, Eun K Lee

Bioorg Med Chem Lett· May 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of a 3-amino-8-azabicyclo[3.2.1]octane replacement in the CCR5 antagonist maraviroc.
Rémy C Lemoine, Ann C Petersen, Lina Setti, Thomas Baldinger, Jutta Wanner, David M Rotstein

Bioorg Med Chem Lett· March 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of a 4-aminopiperidine replacement in several series of CCR5 antagonists.
Rémy C Lemoine, Ann C Petersen, Lina Setti, Lijing Chen, Jutta Wanner, David M Rotstein

Bioorg Med Chem Lett· March 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel CCR5 antagonists for the treatment of HIV infection: a review of compounds patented in 2006 - 2008.
Hanbiao Yang, David M Rotstein

Expert Opin Ther Pat· March 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Spiropiperidine CCR5 antagonists.
David M Rotstein, Stephen D Gabriel, Ferenc Makra, Lubov Filonova, Shelley Gleason

Bioorg Med Chem Lett· September 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of a potent, selective and orally bioavailable 3,9-diazaspiro[5.5]undeca-2-one CCR5 antagonist.
Hanbiao Yang, Xiao-Fa Lin, Fernando Padilla, Stephen D Gabriel, Gabrielle Heilek, David M Rotstein

Bioorg Med Chem Lett· January 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis