Publications by authors named "Paul Beavis"

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Implantable drug delivery system improves tolerability of anti-CD40/anti-PD1 and chemotherapy in a murine model of breast cancer.
Samantha J Wade, Elahe Minaei, Ashleigh Hope, Ross J Turner, Chelsea Penney, Paul A Beavis

Eur J Pharm Sci· January 2026

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Development of a high-affinity anti-ROR1 variable region for broad anti-cancer immunotherapy.
Joshua K M Wong, Pui Yeng Lam, Elaina Coleborn, Jiya Jose, Louisa Alim, Paul A Beavis

Mol Ther· December 2025

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Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8 T cell immunity against melanoma.
Annabell Bachem, Michele Clarke, Geraldine Kong, Ilaryia Tarasova, Lachlan Dryburgh, Paul A Beavis

Immunity· November 2025

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Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery.
Amanda X Y Chen, Kah Min Yap, Joelle S Kim, Kevin Sek, Yu-Kuan Huang, Paul A Beavis

Nature· August 2025

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Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors.
Kevin Sek, Amanda X Y Chen, Thomas Cole, Jesse D Armitage, Junming Tong, Paul A Beavis

Nat Commun· July 2025

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Interleukin-4 modulates type I interferon to augment antitumor immunity.
Hannah V Newnes, Jesse D Armitage, Anthony C Buzzai, Emma de Jong, Katherine M Audsley, Paul A Beavis

Sci Adv· May 2025

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A metabolic pathway for improving adoptive cellular therapy.
Christina M Scheffler, Paul A Beavis, Phillip K Darcy

Cancer Cell· January 2025

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Intracellular zinc protects tumours from T cell-mediated cytotoxicity.
Emily J Lelliott, Jonathan Naddaf, Katherine Ganio, Jessica Michie, Shelly Wang, Paul A Beavis

Cell Death Differ· December 2024

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A scalable, spin-free approach to generate enhanced induced pluripotent stem cell-derived natural killer cells for cancer immunotherapy.
Gustavo R Rossi, Jane Sun, Cheng-Yu Lin, Joshua Km Wong, Louisa Alim, Paul A Beavis

Immunol Cell Biol· November 2024

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Pharmacologic inhibition of dipeptidyl peptidase 1 (cathepsin C) does not block granzyme-mediated target cell killing by CD8 T or NK cells.
Vivien R Sutton, Sally V Watt, Hedieh Akhlaghi, David C Cipolla, Kuan-Ju Chen, Paul A Beavis

Front Pharmacol· July 2024

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The CD8 T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects.
Willem Van Der Byl, Simone Nüssing, Timothy J Peters, Antonio Ahn, Hanjie Li, Paul A Beavis

Immunity· June 2024

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FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy.
Jack D Chan, Christina M Scheffler, Isabelle Munoz, Kevin Sek, Joel N Lee, Paul A Beavis

Nature· May 2024

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IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development.
Wilford Goh, Harrison Sudholz, Momeneh Foroutan, Sebastian Scheer, Aline Pfefferle, Paul Beavis

Nat Immunol· February 2024

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
Imran G House, Emily B Derrick, Kevin Sek, Amanda X Y Chen, Jasmine Li, Paul A Beavis

Cell Rep· February 2024

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AR eGFP reporter mouse enables elucidation of AR expression dynamics during anti-tumor immune responses.
Kirsten L Todd, Junyun Lai, Kevin Sek, Yu-Kuan Huang, Dane M Newman, Paul A Beavis

Nat Commun· November 2023

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
Imran G House, Emily B Derrick, Kevin Sek, Amanda X Y Chen, Jasmine Li, Paul A Beavis

Cell Rep· August 2023

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Single-cell protein expression profiling resolves circulating and resident memory T cell diversity across tissues and infection contexts.
Maximilien Evrard, Etienne Becht, Raissa Fonseca, Andreas Obers, Simone L Park, Paul Beavis

Immunity· July 2023

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T-like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models.
Deborah Meyran, Joe Jiang Zhu, Jeanne Butler, Daniela Tantalo, Sean MacDonald, Paul A Beavis

Sci Transl Med· April 2023

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The efficacy of combination treatment with elotuzumab and lenalidomide is dependent on crosstalk between natural killer cells, monocytes and myeloma cells.
Kelden Richardson, Simon P Keam, Joe Jiang Zhu, Deborah Meyran, Criselle D'Souza, Paul A Beavis

Haematologica· January 2023

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Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses.
Kah Lok Chan, Juliana Gomez, Chelisa Cardinez, Nishi Kumari, Christina E Sparbier, Paul A Beavis

Cancer Cell· October 2022

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TGFβ and CIS Inhibition Overcomes NK-cell Suppression to Restore Antitumor Immunity.
Fernando Souza-Fonseca-Guimaraes, Gustavo R Rossi, Laura F Dagley, Momeneh Foroutan, Timothy R McCulloch, Paul A Beavis

Cancer Immunol Res· September 2022

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PARP11 interfer(on)es with CAR T cell efficacy.
Isabelle Munoz, Paul A Beavis

Nat Cancer· July 2022

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Distinct modulation of IFNγ-induced transcription by BET bromodomain and catalytic P300/CBP inhibition in breast cancer.
Simon J Hogg, Olga Motorna, Conor J Kearney, Emily B Derrick, Imran G House, Paul A Beavis

Clin Epigenetics· July 2022

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Challenges of Creating New Tumor-Infiltrating Lymphocyte for Combating Breast Cancer.
Paul A Beavis, Emily B Derrick, Sherene Loi

J Clin Oncol· June 2022

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CD4 chimeric antigen receptor T cells in for the long journey.
Amanda Xy Chen, Emily B Derrick, Paul A Beavis, Imran G House

Immunol Cell Biol· May 2022

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