Publications by authors named "David Male"

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A hydrogel model of the human blood-brain barrier using differentiated stem cells.
Nandita Rahatekar Singh, Radka Gromnicova, Andreas Brachner, Igor Kraev, Ignacio A Romero, David Male

PLoS One· April 2023

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Nanocarriers for Delivery of Oligonucleotides to the CNS.
David Male, Radka Gromnicova

Int J Mol Sci· January 2022

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Comparison of polypeptides that bind the transferrin receptor for targeting gold nanocarriers.
Conor McQuaid, Andrea Halsey, Maëva Dubois, Ignacio Romero, David Male

PLoS One· October 2021

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Endothelial-Derived Extracellular Vesicles Induce Cerebrovascular Dysfunction in Inflammation.
David Roig-Carles, Eduard Willms, Ruud D Fontijn, Sarai Martinez-Pacheco, Imre Mäger, David K Male

Pharmaceutics· September 2021

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Age-related ultrastructural neurovascular changes in the female mouse cortex and hippocampus.
Eduardo Frías-Anaya, Radka Gromnicova, Igor Kraev, Vadim Rogachevsky, David K Male

Neurobiol Aging· May 2021

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Tissue distribution and cellular localization of gold nanocarriers with bound oligonucleotides.
Nayab Fatima, Ugur Akcan, Mehmet Kaya, Radka Gromnicova, Jane Loughlin, David Male

Nanomedicine (Lond)· April 2021

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Gold nanocarriers for transport of oligonucleotides across brain endothelial cells.
Nayab Fatima, Radka Gromnicova, Jane Loughlin, Basil Sharrack, David Male

PLoS One· October 2020

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EZH2 inhibition: a promising strategy to prevent cancer immune editing.
Ning Kang, Mark Eccleston, Pier-Luc Clermont, Maryam Latarani, David Kingsley Male

Epigenomics· August 2020

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Cannabidiol Enhances the Passage of Lipid Nanocapsules across the Blood-Brain Barrier Both in Vitro and in Vivo.
Juan Aparicio-Blanco, Ignacio A Romero, David K Male, Karla Slowing, Luis García-García

Mol Pharm· May 2019

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PPARγ agonist-loaded PLGA-PEG nanocarriers as a potential treatment for Alzheimer's disease: in vitro and in vivo studies.
Marcelle Silva-Abreu, Ana Cristina Calpena, Pol Andrés-Benito, Ester Aso, Ignacio A Romero, David Male

Int J Nanomedicine· November 2018

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Transport of Gold Nanoparticles by Vascular Endothelium from Different Human Tissues.
Radka Gromnicova, Mehmet Kaya, Ignacio A Romero, Phil Williams, Simon Satchell, David Male

PLoS One· August 2017

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MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium.
Camilla Cerutti, Laura J Edwards, Helga E de Vries, Basil Sharrack, David K Male

Sci Rep· March 2017

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MicroRNA-155 contributes to shear-resistant leukocyte adhesion to human brain endothelium in vitro.
Camilla Cerutti, Patricia Soblechero-Martin, Dongsheng Wu, Miguel Alejandro Lopez-Ramirez, Helga de Vries, David Kingsley Male

Fluids Barriers CNS· May 2016

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Localization and mobility of glucose-coated gold nanoparticles within the brain.
Radka Gromnicova, Canan Ugur Yilmaz, Nurcan Orhan, Mehmet Kaya, Heather Davies, David Male

Nanomedicine (Lond)· March 2016

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A three-dimensional model of the human blood-brain barrier to analyse the transport of nanoparticles and astrocyte/endothelial interactions.
Peddagangannagari Sreekanthreddy, Radka Gromnicova, Heather Davies, James Phillips, Ignacio A Romero, David Male

F1000Res· February 2016

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Glucose-coated gold nanoparticles transfer across human brain endothelium and enter astrocytes in vitro.
Radka Gromnicova, Heather A Davies, Peddagangannagari Sreekanthreddy, Ignacio A Romero, Torben Lund, David K Male

PLoS One· March 2015

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Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation.
Dongsheng Wu, Camilla Cerutti, Miguel A Lopez-Ramirez, Gareth Pryce, Josh King-Robson, David K Male

J Cereb Blood Flow Metab· March 2015

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MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation.
Miguel Alejandro Lopez-Ramirez, Dongsheng Wu, Gareth Pryce, Julie E Simpson, Arie Reijerkerk, David Kingsley Male

FASEB J· June 2014

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Cytokine-induced changes in the gene expression profile of a human cerebral microvascular endothelial cell-line, hCMEC/D3.
Miguel Alejandro Lopez-Ramirez, David Kingsley Male, Chunfang Wang, Basil Sharrack, Dongsheng Wu

Fluids Barriers CNS· September 2013

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Transcriptional control of the multi-drug transporter ABCB1 by transcription factor Sp3 in different human tissues.
Radka Gromnicova, Ignacio Romero, David Male

PLoS One· May 2013

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Role of caspases in cytokine-induced barrier breakdown in human brain endothelial cells.
M Alejandro Lopez-Ramirez, Roman Fischer, Claudia C Torres-Badillo, Heather A Davies, Karen Logan, David K Male

J Immunol· September 2012

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Expression and induction of p-glycoprotein-1 on cultured human brain endothelium.
David K Male

J Cereb Blood Flow Metab· November 2009

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Polarized P-glycoprotein expression by the immortalised human brain endothelial cell line, hCMEC/D3, restricts apical-to-basolateral permeability to rhodamine 123.
Leon M Tai, P Sreekanth Reddy, M Alejandro Lopez-Ramirez, Heather A Davies, David K Male

Brain Res· October 2009

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P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-beta.
Leon M Tai, A Jane Loughlin, David K Male, Ignacio A Romero

J Cereb Blood Flow Metab· June 2009

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Transcriptional control of occludin expression in vascular endothelia: regulation by Sp3 and YY1.
Hadassah Sade, Karen Holloway, Ignacio A Romero, David Male

Biochim Biophys Acta· March 2009

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