Publications by authors named "David McFadden"

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Loss of heterozygosity exposes germline mutations in complex I and drives Warburg metabolism in oncocytic carcinoma of the thyroid.
Celia de la Calle Arregui, Anderson R Frank, Kelvin Mun, Jiwoong Kim, Kuntal Majmudar, David G McFadden

bioRxiv· December 2025

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Endogenous EWSR1-FLI1 degron alleles enable control of fusion oncoprotein expression in tumor cell lines and xenografts.
James H McGinnis, Alberto Bremauntz Enriquez, Florentina Vandiver, Xin Bai, Jiwoong Kim, David G McFadden

bioRxiv· October 2024

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Forward Genetic Screens Identify Mechanisms of Resistance to Small-Molecule Lactate Dehydrogenase Inhibitors.
Anderson R Frank, Florentina Vandiver, David G McFadden

ACS Chem Biol· February 2024

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Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules.
Thu P Nguyen, Min Fang, Jiwoong Kim, Baiyun Wang, Elisa Lin, David G McFadden

Cell Chem Biol· November 2023

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Forward genetic screens identify mechanisms of resistance to small molecule lactate dehydrogenase inhibitors.
Anderson R Frank, Florentina Vandiver, David G McFadden

bioRxiv· September 2023

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Mitochondrial-Encoded Complex I Impairment Induces a Targetable Dependency on Aerobic Fermentation in Hürthle Cell Carcinoma of the Thyroid.
Anderson R Frank, Vicky Li, Spencer D Shelton, Jiwoong Kim, Gordon M Stott, David G McFadden

Cancer Discov· August 2023

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Scinderin promotes fusion of electron transport chain dysfunctional muscle stem cells with myofibers.
Xun Wang, Spencer D Shelton, Bogdan Bordieanu, Anderson R Frank, Yating Yi, David G McFadden

Nat Aging· July 2023

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Role of Pellino-1 in Inflammation and Cardioprotection following Severe Sepsis: A Novel Mechanism in a Murine Severe Sepsis Model .
Mahesh Thirunavukkarasu, Santosh Swaminathan, Andrew Kemerley, Seetur R Pradeep, Sue Ting Lim, David W McFadden

Cells· June 2023

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Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules.
Thu P Nguyen, Min Fang, Jiwoong Kim, Baiyun Wang, Elisa Lin, David G McFadden

bioRxiv· February 2023

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Differential requirements for mitochondrial electron transport chain components in the adult murine liver.
Nicholas P Lesner, Xun Wang, Zhenkang Chen, Anderson Frank, Cameron J Menezes, David G McFadden

Elife· September 2022

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TK216 targets microtubules in Ewing sarcoma cells.
Juan Manuel Povedano, Vicky Li, Katherine E Lake, Xin Bai, Rameshu Rallabandi, David G McFadden

Cell Chem Biol· August 2022

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Quality control of image sensors using gaseous tritium light sources.
David McFadden, Brad Amos, Rainer Heintzmann

Philos Trans A Math Phys Eng Sci· April 2022

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Genetics, Diagnosis, and Management of Hürthle Cell Thyroid Neoplasms.
David G McFadden, Peter M Sadow

Front Endocrinol (Lausanne)· February 2022

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Symptoms COVID 19 Positive Vapers Compared to COVID 19 Positive Non-vapers.
David D McFadden, Shari L Bornstein, Robert Vassallo, Bradley R Salonen, Mohammed Nadir Bhuiyan

J Prim Care Community Health· January 2022

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Engineered resveratrol-loaded fibrous scaffolds promotes functional cardiac repair and regeneration through Thioredoxin-1 mediated VEGF pathway.
Jacob D Campbell, Rajesh Lakshmanan, Vaithinathan Selvaraju, Diego Accorsi, David W McFadden

Int J Pharm· March 2021

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Mitochondrial DNA Haplotypes as Genetic Modifiers of Cancer.
Alpaslan Tasdogan, David G McFadden, Prashant Mishra

Trends Cancer· December 2020

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A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins.
Juan Manuel Povedano, Rameshu Rallabandi, Xin Bai, Xuecheng Ye, Joel Liou, David G McFadden

J Med Chem· November 2020

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Game Theory and Neurosurgery.
Ketan R Bulsara, David W McFadden

Oper Neurosurg· September 2020

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Deletion of newly described pro-survival molecule Pellino-1 increases oxidative stress, downregulates cIAP2/NF-κB cell survival pathway, reduces angiogenic response, and thereby aggravates tissue function in mouse ischemic models.
Vaithinathan Selvaraju, Mahesh Thirunavukkarasu, Mandip Joshi, Babatunde Oriowo, Inam A Shaikh, David W McFadden

Basic Res Cardiol· June 2020

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New Approaches to SCLC Therapy: From the Laboratory to the Clinic.
John T Poirier, Julie George, Taofeek K Owonikoko, Anton Berns, Elisabeth Brambilla, David McFadden

J Thorac Oncol· April 2020

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Erratum to ``Surgical care of the geriatric patient'' [YMSG 56(7) (2019) 260-329].
Marilyn Katz, Nicole Silverstein, Patrick Coll, Gail Sullivan, Eric M Mortensen, David W McFadden

Curr Probl Surg· December 2019

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Engineering Forward Genetics into Cultured Cancer Cells for Chemical Target Identification.
Juan Manuel Povedano, Joel Liou, David Wei, Ashwin Srivatsav, Jiwoong Kim, David G McFadden

Cell Chem Biol· September 2019

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Surgical care of the geriatric patient.
Marilyn Katz, Nicole Silverstein, Patrick Coll, Gail Sullivan, Eric Girard, David W McFadden

Curr Probl Surg· July 2019

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Paraganglioma of the spermatic cord: A case report and literature review.
Brendan Gontarz, Poornima Hegde, David McFadden

Int J Surg Case Rep· June 2019

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Short Review: Genomic Alterations in Hürthle Cell Carcinoma.
Ian Ganly, David G McFadden

Thyroid· April 2019

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