Publications by authors named "David Messersmith"

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Discovery of a Novel Series of Potent and Selective Alkynylthiazole-Derived PI3Kγ Inhibitors.
Upul K Bandarage, Alex M Aronov, Jingrong Cao, Jon H Come, Kevin M Cottrell, David Messersmith

ACS Med Chem Lett· January 2021

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Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS).
Jon H Come, Philip N Collier, James A Henderson, Albert C Pierce, Robert J Davies, David Messersmith

J Med Chem· June 2018

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Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases.
Luc J Farmer, Mark W Ledeboer, Thomas Hoock, Michael J Arnost, Randy S Bethiel, David Messersmith

J Med Chem· September 2015

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Discovery of Highly Isoform Selective Thiazolopiperidine Inhibitors of Phosphoinositide 3-Kinase γ.
Philip N Collier, David Messersmith, Arnaud Le Tiran, Upul K Bandarage, Christina Boucher

J Med Chem· July 2015

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2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2.
Mark W Ledeboer, Albert C Pierce, John P Duffy, Huai Gao, David Messersmith

Bioorg Med Chem Lett· December 2009

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Versatile and facile synthesis of diverse semisynthetic tetracycline derivatives via Pd-catalyzed reactions.
Mark L Nelson, Mohamed Y Ismail, Laura McIntyre, Beena Bhatia, Peter Viski, David Messersmith

J Org Chem· July 2003

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