Publications by authors named "David Mortenson"

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A highly selective TCR-mimic antibody reveals unexpected mechanisms of HBV peptide-MHC recognition and previously unknown target biology.
Shahzada Khan, Jeremy Lum, Heather Stephenson, Pawan Bir Kohli, David Mortenson

MAbs· December 2025

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Development of a PRAME pMHC targeted T cell engager for solid tumor therapy.
Katarzyna Skrzypczynska, Kristin Schimert, Heather Stephenson, In Kyoung Mah, David Mortenson

MAbs· December 2025

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Lysine carbamoylation during urea denaturation remodels the energy landscape of human transthyretin dissociation linked to unfolding.
Marcus Jäger, David E Mortenson, Maziar S Ardejani, Gabriel M Kline, Maria T Dendle

Protein Sci· April 2025

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Using sulfuramidimidoyl fluorides that undergo sulfur(VI) fluoride exchange for inverse drug discovery.
Gabriel J Brighty, Rachel C Botham, Suhua Li, Luke Nelson, David E Mortenson

Nat Chem· October 2020

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Publisher Correction: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Amado Carreras-Sureda, Fabián Jaña, Hery Urra, Sylvere Durand, David E Mortenson

Nat Cell Biol· July 2019

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Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Amado Carreras-Sureda, Fabián Jaña, Hery Urra, Sylvere Durand, David E Mortenson

Nat Cell Biol· June 2019

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Stabilization of amyloidogenic immunoglobulin light chains by small molecules.
Gareth J Morgan, Nicholas L Yan, David E Mortenson, Enrico Rennella, Joshua M Blundon

Proc Natl Acad Sci U S A· April 2019

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A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
Dale F Kreitler, Zhihui Yao, Jay D Steinkruger, David E Mortenson, Lijun Huang

J Am Chem Soc· January 2019

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Evaluation of β-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure.
David E Mortenson, Dale F Kreitler, Nicole C Thomas, Ilia A Guzei, Samuel H Gellman

Chembiochem· March 2018

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"Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates.
David E Mortenson, Gabriel J Brighty, Lars Plate, Grant Bare, Wentao Chen

J Am Chem Soc· January 2018

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Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.
Stephen Connelly, David E Mortenson, Sungwook Choi, Ian A Wilson, Evan T Powers

Bioorg Med Chem Lett· August 2017

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Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue.
Wentao Chen, Jiajia Dong, Lars Plate, David E Mortenson, Gabriel J Brighty

J Am Chem Soc· June 2016

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The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
Che-Hsiung Hsu, Sangho Park, David E Mortenson, B Lachele Foley, Xiaocong Wang

J Am Chem Soc· June 2016

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Effects of Single α-to-β Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.
Dale F Kreitler, David E Mortenson, Katrina T Forest, Samuel H Gellman

J Am Chem Soc· May 2016

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High-resolution structures of a heterochiral coiled coil.
David E Mortenson, Jay D Steinkruger, Dale F Kreitler, Dominic V Perroni, Gregory P Sorenson

Proc Natl Acad Sci U S A· October 2015

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Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif.
Zvi Hayouka, Nicole C Thomas, David E Mortenson, Kenneth A Satyshur, Bernard Weisblum

J Am Chem Soc· September 2015

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Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain.
David E Mortenson, Dale F Kreitler, Hyun Gi Yun, Samuel H Gellman, Katrina T Forest

Acta Crystallogr D Biol Crystallogr· December 2013

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Evidence for phenylalanine zipper-mediated dimerization in the X-ray crystal structure of a magainin 2 analogue.
Zvi Hayouka, David E Mortenson, Dale F Kreitler, Bernard Weisblum, Katrina T Forest

J Am Chem Soc· October 2013

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Differential impact of β and γ residue preorganization on α/β/γ-peptide helix stability in water.
Young-Hee Shin, David E Mortenson, Kenneth A Satyshur, Katrina T Forest, Samuel H Gellman

J Am Chem Soc· June 2013

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Enhancement of α-helix mimicry by an α/β-peptide foldamer via incorporation of a dense ionic side-chain array.
Lisa M Johnson, David E Mortenson, Hyun Gi Yun, W Seth Horne, Thomas J Ketas

J Am Chem Soc· May 2012

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Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations.
David E Mortenson, Kenneth A Satyshur, Ilia A Guzei, Katrina T Forest, Samuel H Gellman

J Am Chem Soc· February 2012

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Enzyme-amplified array sensing of proteins in solution and in biofluids.
Oscar R Miranda, Hung-Ting Chen, Chang-Cheng You, David E Mortenson, Xiao-Chao Yang

J Am Chem Soc· April 2010

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