Publications by authors named "Jeremy Lum"

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A highly selective TCR-mimic antibody reveals unexpected mechanisms of HBV peptide-MHC recognition and previously unknown target biology.
Shahzada Khan, Jeremy Lum, Heather Stephenson, Pawan Bir Kohli, David Mortenson

MAbs· December 2025

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From translation to stabilization and degradation: A multifaceted approach for the treatment of superoxide dismutase 1-associated amyotrophic lateral sclerosis.
Christen G Chisholm, Luke McAlary, Jeremy S Lum

Neural Regen Res· November 2025

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Development of a targeted BioPROTAC degrader selective for misfolded SOD1.
Christen G Chisholm, Rachael Bartlett, Mikayla L Brown, Emma-Jayne Proctor, Natalie E Farrawell, Jeremy S Lum

Nat Commun· November 2025

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Subcellular mass spectrometry imaging of lipids and nucleotides using transmission geometry ambient laser desorption and plasma ionisation.
Reuben S E Young, Ann-Katrin Piper, Luke McAlary, Jayden C McKinnon, Jeremy S Lum

Nat Commun· October 2025

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CoREST3 exhibits isoform specific expression in Alzheimer's disease and regulation of HDAC2.
Simon Maksour, Helena Targa Dias Anastacio, Jeremy S Lum, Samara Walpole, Kelly A Newell

BMC Biol· August 2025

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A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosis.
Jeremy S Lum, Mikayla L Brown, Natalie E Farrawell, Rachael Bartlett, Christen G Chisholm

EBioMedicine· May 2025

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In-Gel Zymography of Amyotrophic Lateral Sclerosis-Associated Variants of Superoxide Dismutase-1.
Jeremy S Lum, Mikayla L Brown, Siobhan C Suters, Justin J Yerbury, Luke McAlary

Methods Mol Biol· April 2025

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Lipid nanoparticles and transcranial focused ultrasound enhance the delivery of SOD1 antisense oligonucleotides to the murine brain for ALS therapy.
Gayathri R Ediriweera, Amal J Sivaram, Gary Cowin, Mikayla L Brown, Luke McAlary, Jeremy S Lum

J Control Release· February 2025

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MALDI-2-Enabled Oversampling for the Mass Spectrometry Imaging of Metabolites at Single-Cell Resolution.
Jayden C McKinnon, Rachelle Balez, Reuben S E Young, Mikayla L Brown, Jeremy S Lum

J Am Soc Mass Spectrom· November 2024

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Ubiquitin homeostasis disruption, a common cause of proteostasis collapse in amyotrophic lateral sclerosis?
Christen G Chisholm, Jeremy S Lum, Natalie E Farrawell, Justin J Yerbury

Neural Regen Res· October 2022

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Misfolding at the synapse: A role in amyotrophic lateral sclerosis pathogenesis?
Jeremy S Lum, Justin J Yerbury

Front Mol Neurosci· September 2022

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Cells Overexpressing ALS-Associated SOD1 Variants Are Differentially Susceptible to CuATSM-Associated Toxicity.
Mikayla L Brown, Luke McAlary, Jeremy S Lum, Natalie E Farrawell, Justin J Yerbury

ACS Chem Neurosci· August 2022

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Vulnerability of the spinal motor neuron presynaptic terminal sub-proteome in ALS.
Jeremy S Lum, Tracey Berg, Christen G Chisholm, Michele Vendruscolo, Justin J Yerbury

Neurosci Lett· May 2022

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An Optimized Direct Lysis Gene Expression Microplate Assay and Applications for Disease, Differentiation, and Pharmacological Cell-Based Studies.
Neville S Ng, Simon Maksour, Jeremy S Lum, Michelle Newbery, Victoria Shephard

Biosensors (Basel)· May 2022

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CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1 mice with a C57BL/6 background.
Jeremy S Lum, Mikayla L Brown, Natalie E Farrawell, Luke McAlary, Diane Ly

Sci Rep· September 2021

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Prenatal methadone exposure impairs adolescent cognition and GABAergic neurodevelopment in a novel rat model of maternal methadone treatment.
Jeremy S Lum, Katrina M Bird, Jennifer Wilkie, Samuel J Millard, Sachie Pallimulla

Prog Neuropsychopharmacol Biol Psychiatry· August 2021

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The effects of perinatal fluoxetine exposure on emotionality behaviours and cortical and hippocampal glutamatergic receptors in female Sprague-Dawley and Wistar-Kyoto rats.
Samuel J Millard, Jeremy S Lum, Francesca Fernandez, Katrina Weston-Green, Kelly A Newell

Prog Neuropsychopharmacol Biol Psychiatry· June 2021

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Sex differences in the neurochemistry of frontal cortex: Impact of early life stress.
Christina J Perry, Erin J Campbell, Katherine D Drummond, Jeremy S Lum, Jee Hyun Kim

J Neurochem· May 2021

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Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS.
Natalie E Farrawell, Luke McAlary, Jeremy S Lum, Christen G Chisholm, Sadaf T Warraich

iScience· November 2020

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Amyotrophic Lateral Sclerosis: Proteins, Proteostasis, Prions, and Promises.
Luke McAlary, Yee Lian Chew, Jeremy Stephen Lum, Nicholas John Geraghty, Justin John Yerbury

Front Cell Neurosci· November 2020

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Supplement of microbiota-accessible carbohydrates prevents neuroinflammation and cognitive decline by improving the gut microbiota-brain axis in diet-induced obese mice.
Hongli Shi, Qiao Wang, Mingxuan Zheng, Shanshan Hao, Jeremy S Lum

J Neuroinflammation· March 2020

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Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia.
Ashleigh L Osborne, Nadia Solowij, Ilijana Babic, Jeremy S Lum, Kelly A Newell

Prog Neuropsychopharmacol Biol Psychiatry· December 2019

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Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders.
Ashleigh L Osborne, Nadia Solowij, Ilijana Babic, Jeremy S Lum, Xu-Feng Huang

Brain Behav Immun· October 2019

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Increased translocator protein (TSPO) binding throughout neurodevelopment in the perinatal phencyclidine rodent model of schizophrenia.
Jeremy S Lum, Teresa M du Bois, Filomena Mattner, Andrew Katsifis, Samara J Brown

Schizophr Res· October 2019

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Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model of depression.
Samuel J Millard, Jeremy S Lum, Francesca Fernandez, Katrina Weston-Green, Kelly A Newell

J Psychopharmacol· February 2019

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