Publications by authors named "David Munn"

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Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33.
Sara Lamorte, Rene Quevedo, Robbie Jin, Luke Neufeld, Zhe Qi Liu, David H Munn

Cancer Cell· May 2025

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β-blocker suppresses both tumoral sympathetic neurons and perivascular macrophages during oncolytic herpes virotherapy.
Konstantina Kyritsi, Rafal Pacholczyk, Eugene Douglass, Miao Yu, Hui Fang, David H Munn

J Immunother Cancer· April 2025

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Brain CD73 modulates interferon signaling to regulate glioblastoma invasion.
Konstantina Kyritsi, Jishi Ye, Eugene Douglass, Rafal Pacholczyk, Nobushige Tsuboi, David H Munn

Neurooncol Adv· April 2025

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Blocking Feedback Immunosuppression of Antigen Presentation in Brain Tumor During Oncolytic Virotherapy with oHSV-mshPKR.
Nobushige Tsuboi, Kimberly A Rivera-Caraballo, Upasana Sahu, Rafal Pacholczyk, Eugene Douglass, David H Munn

Mol Cancer Ther· March 2025

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UFL1 promotes survival and function of virtual memory CD8 T cells.
Brinda Bhatt, Kunal Kumar, Huidong Shi, Dhasarathan Ganesan, Francis Anazodo, David H Munn

J Immunol· March 2025

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Indoximod-based chemo-immunotherapy for pediatric brain tumors: A first-in-children phase I trial.
Theodore S Johnson, Tobey J MacDonald, Rafal Pacholczyk, Dolly Aguilera, Ahmad Al-Basheer, David H Munn

Neuro Oncol· February 2024

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Outcomes of total hip and knee arthroplasty in patients with haemophilia: A meta-analysis of comparative studies and clinical practice recommendations.
Dimitris Challoumas, David Munn, Gowsikan Jeyakumar, Catherine Bagot, Ryan Rodgers

Haemophilia· January 2024

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Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer.
Nada H Eisa, Vincent M Crowley, Asif Elahi, Vamsi Krishna Kommalapati, Michael A Serwetnyk, David Munn

iScience· December 2023

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The Simple prEservatioN of Single cElls method for cryopreservation enables the generation of single-cell immune profiles from whole blood.
Sarthak Satpathy, Beena E Thomas, William J Pilcher, Mojtaba Bakhtiari, Lori A Ponder, David H Munn

Front Immunol· December 2023

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Outcomes of total hip and knee arthroplasty in special populations: a synopsis and critical appraisal of systematic reviews.
Dimitris Challoumas, David Munn, Henrietta Stockdale, Nigel Ng, Michael McCormick

Arthroplasty· July 2023

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Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment.
John D Klement, Priscilla S Redd, Chunwan Lu, Alyssa D Merting, Dakota B Poschel, David H Munn

Cancer Cell· March 2023

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Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses.
Jessica K Mandula, Shiun Chang, Eslam Mohamed, Rachel Jimenez, Rosa A Sierra-Mondragon, David H Munn

Cancer Cell· October 2022

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Retinoic acid signaling acts as a rheostat to balance Treg function.
Govindarajan Thangavelu, Gabriela Andrejeva, Sara Bolivar-Wagers, Sujeong Jin, Michael C Zaiken, David H Munn

Cell Mol Immunol· July 2022

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Indomethacin-induced oxidative stress enhances death receptor 5 signaling and sensitizes tumor cells to adoptive T-cell therapy.
Nada S Aboelella, Caitlin Brandle, Ogacheko Okoko, Md Yeashin Gazi, Zhi-Chun Ding, David H Munn

J Immunother Cancer· July 2022

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BET-bromodomain and EZH2 inhibitor-treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes.
Michael C Zaiken, Ryan Flynn, Katelyn G Paz, Stephanie Y Rhee, Sujeong Jin, David H Munn

Blood· May 2022

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Inhibition of the BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage dendritic cells and enhances anti-tumor T cell immunity.
Madhav D Sharma, Rafal Pacholczyk, Huidong Shi, Zuzana J Berrong, Yousef Zakharia, David H Munn

Immunity· October 2021

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Immunosuppressive metabolites in tumoral immune evasion: redundancies, clinical efforts, and pathways forward.
Maria Rain Jennings, David Munn, John Blazeck

J Immunother Cancer· October 2021

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Phase II trial of the IDO pathway inhibitor indoximod plus pembrolizumab for the treatment of patients with advanced melanoma.
Yousef Zakharia, Robert R McWilliams, Olivier Rixe, Joseph Drabick, Montaser F Shaheen, David Munn

J Immunother Cancer· June 2021

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Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses.
Govindarajan Thangavelu, Chao Wang, Michael Loschi, Asim Saha, Mark J Osborn, David H Munn

Blood· February 2021

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Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma.
Erik Ladomersky, Lijie Zhai, Kristen L Lauing, April Bell, Jiahui Xu, David H Munn

Clin Cancer Res· October 2020

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p50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy.
Chunwan Lu, John D Klement, Alyssa D Smith, Dafeng Yang, Jennifer L Waller, David H Munn

J Immunother Cancer· October 2020

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Persistent STAT5 activation reprograms the epigenetic landscape in CD4 T cells to drive polyfunctionality and antitumor immunity.
Zhi-Chun Ding, Huidong Shi, Nada S Aboelella, Kateryna Fesenkova, Eun-Jeong Park, David H Munn

Sci Immunol· October 2020

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Delayed Akt suppression in the lipopolysaccharide-induced acute lung injury promotes resolution that is associated with enhanced effector regulatory T cells.
Sandeep Artham, Arti Verma, Abdulrahman Alwhaibi, Mir S Adil, Santhakumar Manicassamy, David H Munn

Am J Physiol Lung Cell Mol Physiol· April 2020

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The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling.
Eslam Mohamed, Rosa A Sierra, Jimena Trillo-Tinoco, Yu Cao, Patrick Innamarato, David H Munn

Immunity· April 2020

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CD73 on cancer-associated fibroblasts enhanced by the A-mediated feedforward circuit enforces an immune checkpoint.
Miao Yu, Gang Guo, Lei Huang, Libin Deng, Chang-Sheng Chang, David H Munn

Nat Commun· January 2020

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