Publications by authors named "David Noske"

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Challenges to determine synergistic drug interactions in mice.
Bart A Westerman, Yoran Broersma, Tom Wurdinger, David Noske, Peter Sminia

Nat Commun· September 2025

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Combined inactivation of MEK and mTOR can lead to synergistic cell death in glioblastoma models and associates with NF1-deficiency and a mesenchymal subtype.
Fleur M G Cornelissen, Yoran Broersma, Ravi S Narayan, Rogier Dik, Sander R Piersma, David Noske

Mol Cancer Ther· August 2025

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Combined Inactivation of MEK and mTOR Can Lead to Synergistic Cell Death in Glioblastoma Models and Associates with NF1 Deficiency and a Mesenchymal Subtype.
Fleur M G Cornelissen, Yoran Broersma, Ravi S Narayan, Rogier Dik, Sander R Piersma, David Noske

Mol Cancer Ther· August 2025

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The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets.
Jaco C Knol, Mengge Lyu, Franziska Böttger, Madalena Nunes Monteiro, Thang V Pham, David P Noske

Cancer Cell· July 2025

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Liquid biopsies for the monitoring of gliomas and brain metastases in adults.
Govert Dwarshuis, Lente L Kroon, Dieta Brandsma, David P Noske, Myron G Best

Acta Neuropathol· April 2025

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The translatome of glioblastoma.
Fleur M G Cornelissen, Zhaoren He, Edward Ciputra, Richard R de Haas, Ammarina Beumer-Chuwonpad, David Noske

Mol Oncol· March 2025

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Arming AAV9 with a Single-Chain Fragment Variable Antibody Against PD-1 for Systemic Glioblastoma Therapy.
Semer Maksoud, Markus W Schweiger, Elie I Tabet, Tianhe Xiao, Joelle El Hokayem, David P Noske

Mol Neurobiol· February 2025

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Adenovirus-Neutralizing and Infection-Promoting Activities Measured in Serum of Human Brain Cancer Patients Treated with Oncolytic Adenovirus Ad5-∆24.RGD.
Ida H van der Meulen-Muileman, Joana Amado-Azevedo, Martine L M Lamfers, Anne Kleijn, Sander Idema, David P Noske

Int J Mol Sci· January 2025

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Adapting to Adulthood: A Review of Transition Strategies for Osteogenesis Imperfecta.
Luca Celli, Mark R Garrelfs, Ralph J B Sakkers, Mariet W Elting, Mauro Celli, David P Noske

Calcif Tissue Int· December 2024

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Oncogenic composite mutations can be predicted by co-mutations and their chromosomal location.
Asli Küçükosmanoglu, Carolien L van der Borden, Lisanne E A de Boer, Roel Verhaak, David Noske

Mol Oncol· October 2024

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A Real-world Toxicity Atlas Shows that Adverse Events of Combination Therapies Commonly Result in Additive Interactions.
Asli Küçükosmanoglu, Silvia Scoarta, Megan Houweling, Nicoleta Spinu, Thomas Wijnands, David Noske

Clin Cancer Res· April 2024

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Glioblastoma extracellular vesicles modulate immune PD-L1 expression in accessory macrophages upon radiotherapy.
Markus W Schweiger, Zohreh Amoozgar, Pierre Repiton, Robert Morris, Semer Maksoud, David P Noske

iScience· February 2024

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The immunological landscape of peripheral blood in glioblastoma patients and immunological consequences of age and dexamethasone treatment.
Sophie A Dusoswa, Jan Verhoeff, Saskia van Asten, Joyce Lübbers, Marlous van den Braber, David Noske

Front Immunol· February 2024

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Longitudinal drug synergy assessment using convolutional neural network image-decoding of glioblastoma single-spheroid cultures.
Anna Giczewska, Krzysztof Pastuszak, Megan Houweling, Kulsoom U Abdul, Noa Faaij, David Noske

Neurooncol Adv· November 2023

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Human voltage-gated Na and K channel properties underlie sustained fast AP signaling.
René Wilbers, Verjinia D Metodieva, Sarah Duverdin, Djai B Heyer, Anna A Galakhova, David P Noske

Sci Adv· October 2023

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Structural and functional specializations of human fast-spiking neurons support fast cortical signaling.
René Wilbers, Anna A Galakhova, Stan L W Driessens, Tim S Heistek, Verjinia D Metodieva, David P Noske

Sci Adv· October 2023

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Local delivery of hrBMP4 as an anticancer therapy in patients with recurrent glioblastoma: a first-in-human phase 1 dose escalation trial.
Eelke M Bos, Elena Binda, Iris S C Verploegh, Eva Wembacher, Daphna Hoefnagel, David Noske

Mol Cancer· August 2023

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Discrimination Between Pre- and Postcapillary Pulmonary Hypertension Using Platelet RNA.
Mohammad Arkani, Azar Kianzad, Samara Jansen, Josien Smit, Edward Post, David P Noske

J Am Heart Assoc· July 2023

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Genes associated with cognitive ability and HAR show overlapping expression patterns in human cortical neuron types.
Stan L W Driessens, Anna A Galakhova, Djai B Heyer, Isabel J Pieterse, René Wilbers, David P Noske

Nat Commun· July 2023

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Explaining Blood-Brain Barrier Permeability of Small Molecules by Integrated Analysis of Different Transport Mechanisms.
Fleur M G Cornelissen, Greta Markert, Ghislaine Deutsch, Maria Antonara, Noa Faaij, David Noske

J Med Chem· June 2023

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Tumor-educated platelet blood tests for Non-Small Cell Lung Cancer detection and management.
Mafalda Antunes-Ferreira, Silvia D'Ambrosi, Mohammad Arkani, Edward Post, Sjors G J G In 't Veld, David P Noske

Sci Rep· June 2023

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Screening of predicted synergistic multi-target therapies in glioblastoma identifies new treatment strategies.
Megan Houweling, Anna Giczewska, Kulsoom Abdul, Ninke Nieuwenhuis, Asli Küçükosmanoglu, David Noske

Neurooncol Adv· June 2023

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Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex.
Sarah Hunt, Yoni Leibner, Eline J Mertens, Natalí Barros-Zulaica, Lida Kanari, David P Noske

Cereb Cortex· March 2023

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ALL-tRNAseq enables robust tRNA profiling in tissue samples.
Chantal Scheepbouwer, Ernesto Aparicio-Puerta, Cristina Gomez-Martin, Heleen Verschueren, Monique van Eijndhoven, David P Noske

Genes Dev· March 2023

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Detection and localization of early- and late-stage cancers using platelet RNA.
Sjors G J G In 't Veld, Mohammad Arkani, Edward Post, Mafalda Antunes-Ferreira, Silvia D'Ambrosi, David P Noske

Cancer Cell· September 2022

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