Publications by authors named "David R Howlett"

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Hexapeptides from mammalian inhibitory hormone hunt activate and inactivate nematode reproduction.
John E Hart, Sharad Mohan, Keith G Davies, Ben Ferneyhough, Iain J Clarke, David R Howlett

PLoS One· December 2022

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Cerebral amyloid angiopathy distribution in older people: A cautionary note.
Vafa Alakbarzade, Jonathan Mr French, David R Howlett, Johannes Attems, Paul T Francis

Alzheimers Dement (N Y)· February 2021

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Epitope mapping of an uncertain endogenous antigen implies secretogranin II peptide splicing.
David R Howlett, Iain J Clarke, Russell P Newton, John E Hart

F1000Res· June 2020

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Increased Levels of Brain Adrenomedullin in the Neuropathology of Alzheimer's Disease.
Hilda Ferrero, Ignacio M Larrayoz, Eva Martisova, Maite Solas, David R Howlett

Mol Neurobiol· June 2018

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Reduction of RPT6/S8 (a Proteasome Component) and Proteasome Activity in the Cortex is Associated with Cognitive Impairment in Lewy Body Dementia.
Amani Alghamdi, Julie Vallortigara, David R Howlett, Martin Broadstock, Tibor Hortobágyi

J Alzheimers Dis· February 2018

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PET Imaging of Copper Trafficking in a Mouse Model of Alzheimer Disease.
Julia Baguña Torres, Erica M Andreozzi, Joel T Dunn, Muhammad Siddique, Istvan Szanda, David R Howlett

J Nucl Med· January 2016

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Regional Multiple Pathology Scores Are Associated with Cognitive Decline in Lewy Body Dementias.
David R Howlett, David Whitfield, Mary Johnson, Johannes Attems, John T O'Brien

Brain Pathol· July 2015

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Spreading pathologies precede cognitive decline in Alzheimer's disease.
David R Howlett, Johannes Attems, Paul T Francis

Biol Psychiatry· April 2015

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Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing.
Carla J Cox, Fahd Choudhry, Eleanor Peacey, Michael S Perkinton, Jill C Richardson, David R Howlett

Neurobiol Aging· January 2015

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Decreased immunoreactivities of neocortical AMPA receptor subunits correlate with motor disability in Lewy body dementias.
Nur-Ezan Mohamed, David R Howlett, Lu Ma, Paul T Francis, Dag Aarsland

J Neural Transm (Vienna)· January 2014

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Clusterin associates specifically with Aβ40 in Alzheimer's disease brain tissue.
David R Howlett, Tibor Hortobágyi, Paul T Francis

Brain Pathol· November 2013

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Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model.
Elisa Dassie, Melissa R Andrews, Jean-Charles Bensadoun, Matthias Cacquevel, Bernard L Schneider, David R Howlett

Neurobiol Aging· May 2013

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Pro-oxidant diet enhances β/γ secretase-mediated APP processing in APP/PS1 transgenic mice.
Fahd Choudhry, David R Howlett, Jill C Richardson, Paul T Francis, Robert J Williams

Neurobiol Aging· May 2012

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Synaptic protein expression is regulated by a pro-oxidant diet in APPxPS1 mice.
Martin Broadstock, Rikke Lewinsky, Emma L Jones, Cathy Mitchelmore, David R Howlett

J Neural Transm (Vienna)· April 2012

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Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice.
Paul J Meakin, Alex J Harper, D Lee Hamilton, Jennifer Gallagher, Alison D McNeilly, David R Howlett

Biochem J· January 2012

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Neurochemical changes in a double transgenic mouse model of Alzheimer's disease fed a pro-oxidant diet.
Elizabeth S Ash, Mohammad S Alavijeh, Alan M Palmer, Cathy Mitchelmore, David R Howlett

Neurochem Int· November 2010

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Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease.
Madhav Thambisetty, Andrew Simmons, Latha Velayudhan, Abdul Hye, James Campbell, David R Howlett

Arch Gen Psychiatry· July 2010

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Longitudinal regional brain volume changes quantified in normal aging and Alzheimer's APP x PS1 mice using MRI.
Satheesh Maheswaran, Hervé Barjat, Daniel Rueckert, Simon T Bate, David R Howlett

Brain Res· May 2009

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Abeta(1-42) modulation of Akt phosphorylation via alpha7 nAChR and NMDA receptors.
Jonathan J Abbott, David R Howlett, Paul T Francis, Robert J Williams

Neurobiol Aging· July 2008

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MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease.
Ainsley A Culbert, Stephen D Skaper, David R Howlett, Nicholas A Evans, Laura Facci

J Biol Chem· August 2006

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Imaging and spatial distribution of beta-amyloid peptide and metal ions in Alzheimer's plaques by laser ablation-inductively coupled plasma-mass spectrometry.
Robert W Hutchinson, Alan G Cox, Cameron W McLeod, Peter S Marshall, Alex Harper, David R Howlett

Anal Biochem· November 2005

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Cognitive correlates of Abeta deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes.
David R Howlett, Jill C Richardson, Angela Austin, Andrew A Parsons, Simon T Bate

Brain Res· August 2004

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Cyclin-dependent kinase-5/p35 phosphorylates Presenilin 1 to regulate carboxy-terminal fragment stability.
Kwok-Fai Lau, David R Howlett, Sashi Kesavapany, Claire L Standen, Colin Dingwall

Mol Cell Neurosci· May 2002

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