Publications by authors named "David Rickman"

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Targeting anti-androgen therapy resistance through epigenetic rewiring.
Kate E Dunmore, David S Rickman

Nat Cancer· April 2025

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Increased translation driven by non-canonical EZH2 creates a synthetic vulnerability in enzalutamide-resistant prostate cancer.
Shankha S Chatterjee, Juan F Linares, Tania Cid-Diaz, Angeles Duran, Mohd Imran K Khan, David S Rickman

Nat Commun· November 2024

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The third symposium on treatment-induced neuroendocrine prostate cancer: insights and future directions.
Yuzhuo Wang, Joshua Scurll, Itzel Astiazarán Rascón, Cassandra Cui, Yuchao Ni, David S Rickman

Epigenomics· October 2024

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Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes.
Varadha Balaji Venkadakrishnan, Adam G Presser, Richa Singh, Matthew A Booker, Nicole A Traphagen, David S Rickman

Nat Commun· August 2024

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Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes.
Varadha Balaji Venkadakrishnan, Adam G Presser, Richa Singh, Matthew A Booker, Nicole A Traphagen, David S Rickman

Res Sq· March 2024

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Distinct mesenchymal cell states mediate prostate cancer progression.
Hubert Pakula, Mohamed Omar, Ryan Carelli, Filippo Pederzoli, Giuseppe Nicolò Fanelli, David S Rickman

Nat Commun· January 2024

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The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer.
Lucie Van Emmenis, Sheng-Yu Ku, Kaitlyn Gayvert, Jonathan R Branch, Nicholas J Brady, David S Rickman

Cancer Res Commun· August 2023

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Distinct mesenchymal cell states mediate prostate cancer progression.
Hubert Pakula, Mohamed Omar, Ryan Carelli, Filippo Pederzoli, Giuseppe Nicolò Fanelli, David S Rickman

bioRxiv· April 2023

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Defining cellular population dynamics at single-cell resolution during prostate cancer progression.
Alexandre A Germanos, Sonali Arora, Ye Zheng, Erica T Goddard, Ilsa M Coleman, David S Rickman

Elife· December 2022

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AR-V7 exhibits non-canonical mechanisms of nuclear import and chromatin engagement in castrate-resistant prostate cancer.
Seaho Kim, CheukMan C Au, Mohd Azrin Bin Jamalruddin, Naira Essam Abou-Ghali, Eiman Mukhtar, David S Rickman

Elife· July 2022

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Extracellular Matrix in Synthetic Hydrogel-Based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 Inhibitors.
Matthew J Mosquera, Sungwoong Kim, Rohan Bareja, Zhou Fang, Shuangyi Cai, David S Rickman

Adv Mater· January 2022

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RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer.
Mark P Labrecque, Lisha G Brown, Ilsa M Coleman, Bryce Lakely, Nicholas J Brady, David S Rickman

Cancer Res· September 2021

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Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer.
Nicholas J Brady, Alyssa M Bagadion, Richa Singh, Vincenza Conteduca, Lucie Van Emmenis, David S Rickman

Nat Commun· June 2021

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Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia.
Mayumi Sugita, David C Wilkes, Rohan Bareja, Kenneth W Eng, Sarah Nataraj, David S Rickman

NPJ Precis Oncol· May 2021

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Integrative Molecular Analysis of Patients With Advanced and Metastatic Cancer.
Verena Sailer, Kenneth Wa Eng, Tuo Zhang, Rohan Bareja, David J Pisapia, David Rickman

JCO Precis Oncol· September 2019

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N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer.
Adeline Berger, Nicholas J Brady, Rohan Bareja, Brian Robinson, Vincenza Conteduca, David S Rickman

J Clin Invest· July 2019

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Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target.
Rachel S Lee, Luxi Zhang, Adeline Berger, Mitchell G Lawrence, Jiangning Song, David S Rickman

Neoplasia· April 2019

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Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer.
Loredana Puca, Katie Gavyert, Verena Sailer, Vincenza Conteduca, Etienne Dardenne, David Rickman

Sci Transl Med· March 2019

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A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers.
Himisha Beltran, Clara Oromendia, Daniel C Danila, Bruce Montgomery, Christopher Hoimes, David S Rickman

Clin Cancer Res· January 2019

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The Expanding World of N-MYC-Driven Tumors.
David S Rickman, Johannes H Schulte, Martin Eilers

Cancer Discov· February 2018

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Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle.
Gabriele Büchel, Anne Carstensen, Ka-Yan Mak, Isabelle Roeschert, Eoin Leen, David S Rickman

Cell Rep· December 2017

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A germline FANCA alteration that is associated with increased sensitivity to DNA damaging agents.
David C Wilkes, Verena Sailer, Hui Xue, Hongwei Cheng, Colin C Collins, David S Rickman

Cold Spring Harb Mol Case Stud· September 2017

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Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network.
Priyanka Dhingra, Alexander Martinez-Fundichely, Adeline Berger, Franklin W Huang, Andre Neil Forbes, David S Rickman

Genome Biol· July 2017

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Biology and evolution of poorly differentiated neuroendocrine tumors.
David S Rickman, Himisha Beltran, Francesca Demichelis, Mark A Rubin

Nat Med· June 2017

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N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
Etienne Dardenne, Himisha Beltran, Matteo Benelli, Kaitlyn Gayvert, Adeline Berger, David S Rickman

Cancer Cell· October 2016

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