Publications by authors named "David Rodenhiser"

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Evaluation of DNA Methylation Episignatures for Diagnosis and Phenotype Correlations in 42 Mendelian Neurodevelopmental Disorders.
Erfan Aref-Eshghi, Jennifer Kerkhof, Victor P Pedro, Groupe DI France, Mouna Barat-Houari, David I Rodenhiser

Am J Hum Genet· June 2021

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Evaluation of DNA Methylation Episignatures for Diagnosis and Phenotype Correlations in 42 Mendelian Neurodevelopmental Disorders.
Erfan Aref-Eshghi, Jennifer Kerkhof, Victor P Pedro, , Mouna Barat-Houari, David I Rodenhiser

Am J Hum Genet· March 2020

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DNA methylation signatures in mendelian developmental disorders as a diagnostic bridge between genotype and phenotype.
Bekim Sadikovic, Erfan Aref-Eshghi, Michael A Levy, David Rodenhiser

Epigenomics· April 2019

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Diagnostic Utility of Genome-wide DNA Methylation Testing in Genetically Unsolved Individuals with Suspected Hereditary Conditions.
Erfan Aref-Eshghi, Eric G Bend, Samantha Colaiacovo, Michelle Caudle, Rana Chakrabarti, David I Rodenhiser

Am J Hum Genet· April 2019

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Gene domain-specific DNA methylation episignatures highlight distinct molecular entities of ADNP syndrome.
Eric G Bend, Erfan Aref-Eshghi, David B Everman, R Curtis Rogers, Sara S Cathey, David Rodenhiser

Clin Epigenetics· April 2019

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Peripheral blood epi-signature of Claes-Jensen syndrome enables sensitive and specific identification of patients and healthy carriers with pathogenic mutations in .
Laila C Schenkel, Erfan Aref-Eshghi, Cindy Skinner, Peter Ainsworth, Hanxin Lin, David I Rodenhiser

Clin Epigenetics· February 2019

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The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance.
Erfan Aref-Eshghi, Laila C Schenkel, Hanxin Lin, Cindy Skinner, Peter Ainsworth, David Rodenhiser

Epigenetics· December 2018

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BAFopathies' DNA methylation epi-signatures demonstrate diagnostic utility and functional continuum of Coffin-Siris and Nicolaides-Baraitser syndromes.
Erfan Aref-Eshghi, Eric G Bend, Rebecca L Hood, Laila C Schenkel, Deanna Alexis Carere, David I Rodenhiser

Nat Commun· November 2018

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Genomic DNA Methylation-Derived Algorithm Enables Accurate Detection of Malignant Prostate Tissues.
Erfan Aref-Eshghi, Laila C Schenkel, Peter Ainsworth, Hanxin Lin, David I Rodenhiser

Front Oncol· April 2018

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Identification of epigenetic signature associated with alpha thalassemia/mental retardation X-linked syndrome.
Laila C Schenkel, Kristin D Kernohan, Arran McBride, Ditta Reina, Amanda Hodge, David I Rodenhiser

Epigenetics Chromatin· January 2018

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Genomic DNA Methylation Signatures Enable Concurrent Diagnosis and Clinical Genetic Variant Classification in Neurodevelopmental Syndromes.
Erfan Aref-Eshghi, David I Rodenhiser, Laila C Schenkel, Hanxin Lin, Cindy Skinner

Am J Hum Genet· January 2018

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Clinical Validation of a Genome-Wide DNA Methylation Assay for Molecular Diagnosis of Imprinting Disorders.
Erfan Aref-Eshghi, Laila C Schenkel, Hanxin Lin, Cindy Skinner, Peter Ainsworth, David Rodenhiser

J Mol Diagn· November 2017

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Clinical Validation of Copy Number Variant Detection from Targeted Next-Generation Sequencing Panels.
Jennifer Kerkhof, Laila C Schenkel, Jack Reilly, Sheri McRobbie, Erfan Aref-Eshghi, David Rodenhiser

J Mol Diagn· November 2017

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Constitutional Epi/Genetic Conditions: Genetic, Epigenetic, and Environmental Factors.
Laila C Schenkel, David Rodenhiser, Victoria Siu, Elizabeth McCready, Peter Ainsworth

J Pediatr Genet· March 2017

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DNA methylation analysis in constitutional disorders: Clinical implications of the epigenome.
Laila C Schenkel, David I Rodenhiser, Peter J Ainsworth, Guillaume Paré, Bekim Sadikovic

Crit Rev Clin Lab Sci· November 2016

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Clinical Validation of Fragile X Syndrome Screening by DNA Methylation Array.
Laila C Schenkel, Charles Schwartz, Cindy Skinner, David I Rodenhiser, Peter J Ainsworth

J Mol Diagn· November 2016

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Genome-wide analysis in human colorectal cancer cells reveals ischemia-mediated expression of motility genes via DNA hypomethylation.
Karolina Skowronski, Joseph Andrews, David I Rodenhiser, Brenda L Coomber

PLoS One· November 2015

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Epigenetics, eh! A meeting summary of the Canadian Conference on Epigenetics.
David I Rodenhiser, Nathalie G Bérubé, Mellissa R W Mann

Epigenetics· October 2011

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Gene signatures of breast cancer progression and metastasis.
David I Rodenhiser, Joseph D Andrews, Theodore A Vandenberg, Ann F Chambers

Breast Cancer Res· January 2011

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Human 21T breast epithelial cell lines mimic breast cancer progression in vivo and in vitro and show stage-specific gene expression patterns.
Lesley H Souter, Joseph D Andrews, Guihua Zhang, Amy C Cook, Carl O Postenka, David I Rodenhiser

Lab Invest· August 2010

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Ischemia dysregulates DNA methyltransferases and p16INK4a methylation in human colorectal cancer cells.
Karolina Skowronski, Sonam Dubey, David Rodenhiser, Brenda Coomber

Epigenetics· August 2010

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Multi-platform whole-genome microarray analyses refine the epigenetic signature of breast cancer metastasis with gene expression and copy number.
Joseph Andrews, Wendy Kennette, Jenna Pilon, Alexandra Hodgson, Alan B Tuck, David I Rodenhiser

PLoS One· January 2010

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Lymphatic metastasis of breast cancer cells is associated with differential gene expression profiles that predict cancer stem cell-like properties and the ability to survive, establish and grow in a foreign environment.
Terlika S Pandit, Wendy Kennette, Lisa Mackenzie, Guihua Zhang, Waleed Al-Katib, David I Rodenhiser

Int J Oncol· August 2009

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New clinical and experimental approaches for studying tumor dormancy: does tumor dormancy offer a therapeutic target?
Paul Goss, Alison L Allan, David I Rodenhiser, Paula J Foster, Ann F Chambers

APMIS· November 2008

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Distinct karyotypes in three breast cancer cell lines --21PTCi, 21NTCi, and 21MT-1 --derived from the same patient and representing different stages of tumor progression.
Jie Xu, Lesley H Souter, Ann F Chambers, David I Rodenhiser, Alan B Tuck

Cancer Genet Cytogenet· October 2008

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